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Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory.
Ruan H, Hacohen N, Golub TR, Van Parijs L, Lodish HF.
Diabetes. 2002 May;51(5):1319-36.PMID: 11978627 [PubMed - indexed for MEDLINE]Related articlesFree article
Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction.
Stephens JM, Lee J, Pilch PF.
J Biol Chem. 1997 Jan 10;272(2):971-6.PMID: 8995390 [PubMed - indexed for MEDLINE]Related articlesFree article
Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes.
Ruan H, Zarnowski MJ, Cushman SW, Lodish HF.
J Biol Chem. 2003 Nov 28;278(48):47585-93. Epub 2003 Sep 15.PMID: 12975378 [PubMed - indexed for MEDLINE]Related articlesFree article
Troglitazone antagonizes tumor necrosis factor-alpha-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-kappaB.
Ruan H, Pownall HJ, Lodish HF.
J Biol Chem. 2003 Jul 25;278(30):28181-92. Epub 2003 May 5.PMID: 12732648 [PubMed - indexed for MEDLINE]Related articlesFree article
Antidiabetic thiazolidinediones block the inhibitory effect of tumor necrosis factor-alpha on differentiation, insulin-stimulated glucose uptake, and gene expression in 3T3-L1 cells.
Szalkowski D, White-Carrington S, Berger J, Zhang B.
Endocrinology. 1995 Apr;136(4):1474-81.PMID: 7895657 [PubMed - indexed for MEDLINE]Related articles
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects.
Rotter V, Nagaev I, Smith U.
J Biol Chem. 2003 Nov 14;278(46):45777-84. Epub 2003 Sep 2.PMID: 12952969 [PubMed - indexed for MEDLINE]Related articlesFree article
Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha.
Zhang B, Berger J, Hu E, Szalkowski D, White-Carrington S, Spiegelman BM, Moller DE.
Mol Endocrinol. 1996 Nov;10(11):1457-66.PMID: 8923470 [PubMed - indexed for MEDLINE]Related articles
Tumor necrosis factor-alpha causes insulin receptor substrate-2-mediated insulin resistance and inhibits insulin-induced adipogenesis in fetal brown adipocytes.
Valverde AM, Teruel T, Navarro P, Benito M, Lorenzo M.
Endocrinology. 1998 Mar;139(3):1229-38.PMID: 9492058 [PubMed - indexed for MEDLINE]Related articlesFree article
Opposing effects of tumour necrosis factor alpha and hyperosmolarity on Na+/myo-inositol co-transporter mRNA levels and myo-inositol accumulation by 3T3-L1 adipocytes.
Yorek MA, Dunlap JA, Lowe WL Jr.
Biochem J. 1998 Dec 1;336 ( Pt 2):317-25.PMID: 9820807 [PubMed - indexed for MEDLINE]Related articlesFree article
Lipid mediators of insulin resistance: ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes.
Long SD, Pekala PH.
Biochem J. 1996 Oct 1;319 ( Pt 1):179-84.PMID: 8870666 [PubMed - indexed for MEDLINE]Related articlesFree article
[Expression of TSG-6 gene during 3T3-L1 preadipocyte differentiation and regulative role of tumor necrosis factor-alpha]
Guo XR, Ding SL, Pan XQ, Gong HX, Fei L, Ni YH, Chen RH.
Zhonghua Er Ke Za Zhi. 2004 May;42(5):344-7. Chinese. PMID: 15189690 [PubMed - indexed for MEDLINE]Related articles
Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production.
Chung S, Brown JM, Provo JN, Hopkins R, McIntosh MK.
J Biol Chem. 2005 Nov 18;280(46):38445-56. Epub 2005 Sep 9.PMID: 16155293 [PubMed - indexed for MEDLINE]Related articlesFree article
Tumor necrosis factor-alpha and ceramides in insulin resistance.
Brindley DN, Wang CN, Mei J, Xu J, Hanna AN.
Lipids. 1999;34 Suppl:S85-8.PMID: 10419100 [PubMed - indexed for MEDLINE]Related articles
Signaling pathways through which insulin regulates CCAAT/enhancer binding protein alpha (C/EBPalpha) phosphorylation and gene expression in 3T3-L1 adipocytes. Correlation with GLUT4 gene expression.
Hemati N, Ross SE, Erickson RL, Groblewski GE, MacDougald OA.
J Biol Chem. 1997 Oct 10;272(41):25913-9.PMID: 9325324 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of cell-permeable ceramides and tumor necrosis factor-alpha on insulin signaling and glucose uptake in 3T3-L1 adipocytes.
Wang CN, O'Brien L, Brindley DN.
Diabetes. 1998 Jan;47(1):24-31.PMID: 9421370 [PubMed - indexed for MEDLINE]Related articles
Molecular mechanisms of tumor necrosis factor-alpha-mediated plasminogen activator inhibitor-1 expression in adipocytes.
Pandey M, Loskutoff DJ, Samad F.
FASEB J. 2005 Aug;19(10):1317-9. Epub 2005 May 31.PMID: 15928193 [PubMed - indexed for MEDLINE]Related articlesFree article
Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
Shukla S, Gupta S.
Clin Cancer Res. 2004 May 1;10(9):3169-78.PMID: 15131058 [PubMed - indexed for MEDLINE]Related articlesFree article
Tumor necrosis factor alpha and interleukin 11 secreted by malignant breast epithelial cells inhibit adipocyte differentiation by selectively down-regulating CCAAT/enhancer binding protein alpha and peroxisome proliferator-activated receptor gamma: mechanism of desmoplastic reaction.
Meng L, Zhou J, Sasano H, Suzuki T, Zeitoun KM, Bulun SE.
Cancer Res. 2001 Mar 1;61(5):2250-5.PMID: 11280794 [PubMed - indexed for MEDLINE]Related articlesFree article
Plasminogen activator inhibitor-1 modulates adipocyte differentiation.
Liang X, Kanjanabuch T, Mao SL, Hao CM, Tang YW, Declerck PJ, Hasty AH, Wasserman DH, Fogo AB, Ma LJ.
Am J Physiol Endocrinol Metab. 2006 Jan;290(1):E103-E113. Epub 2005 Sep 6.PMID: 16144810 [PubMed - indexed for MEDLINE]Related articlesFree article
Transcription suppression of peroxisome proliferator-activated receptor gamma2 gene expression by tumor necrosis factor alpha via an inhibition of CCAAT/ enhancer-binding protein delta during the early stage of adipocyte differentiation.
Kudo M, Sugawara A, Uruno A, Takeuchi K, Ito S.
Endocrinology. 2004 Nov;145(11):4948-56. Epub 2004 Jul 29.PMID: 15284209 [PubMed - indexed for MEDLINE]Related articlesFree article
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