PubMed

Administration of neutral protamine Hagedorn insulin at bedtime versus with dinner in type 1 diabetes mellitus to avoid nocturnal hypoglycemia and improve control. A randomized, controlled trial.

Fanelli CG, Pampanelli S, Porcellati F, Rossetti P, Brunetti P, Bolli GB.

Ann Intern Med. 2002 Apr 2;136(7):504-14.PMID: 11926785 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of QD insulin detemir or neutral protamine Hagedorn on blood glucose control in patients with type I diabetes mellitus using a basal-bolus regimen.

Russell-Jones D, Simpson R, Hylleberg B, Draeger E, Bolinder J.

Clin Ther. 2004 May;26(5):724-36.PMID: 15220016 [PubMed - indexed for MEDLINE]Related articles

Less nocturnal hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compared with bedtime NPH insulin during insulin combination therapy in type 2 diabetes. HOE 901/3002 Study Group.

Yki-Järvinen H, Dressler A, Ziemen M; HOE 901/300s Study Group.

Diabetes Care. 2000 Aug;23(8):1130-6.PMID: 10937510 [PubMed - indexed for MEDLINE]Related articlesFree article

Glimepiride combined with morning insulin glargine, bedtime neutral protamine hagedorn insulin, or bedtime insulin glargine in patients with type 2 diabetes. A randomized, controlled trial.

Fritsche A, Schweitzer MA, Häring HU; 4001 Study Group.

Ann Intern Med. 2003 Jun 17;138(12):952-9.PMID: 12809451 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of multiple daily injection therapy with Humalog mixtures versus separately injected insulin lispro and NPH insulin in adults with type I diabetes mellitus.

Roach P, Bai S, Charbonnel B, Consoli A, Taboga C, Tiengo A, Bolli G; High Mix Study Group.

Clin Ther. 2004 Apr;26(4):502-10.PMID: 15189747 [PubMed - indexed for MEDLINE]Related articles

Intensive replacement of basal insulin in patients with type 1 diabetes given rapid-acting insulin analog at mealtime: a 3-month comparison between administration of NPH insulin four times daily and glargine insulin at dinner or bedtime.

Rossetti P, Pampanelli S, Fanelli C, Porcellati F, Costa E, Torlone E, Scionti L, Bolli GB.

Diabetes Care. 2003 May;26(5):1490-6.PMID: 12716810 [PubMed - indexed for MEDLINE]Related articlesFree article

Optimization of evening insulin dose in patients using the short-acting insulin analog lispro.

Ahmed AB, Mallias J, Home PD.

Diabetes Care. 1998 Jul;21(7):1162-6.PMID: 9653613 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of three multiple injection regimens for Type 1 diabetes: morning plus dinner or bedtime administration of insulin detemir vs. morning plus bedtime NPH insulin.

Pieber TR, Draeger E, Kristensen A, Grill V.

Diabet Med. 2005 Jul;22(7):850-7.PMID: 15975098 [PubMed - indexed for MEDLINE]Related articles

Mealtime 50/50 basal + prandial insulin analogue mixture with a basal insulin analogue, both plus metformin, in the achievement of target HbA1c and pre- and postprandial blood glucose levels in patients with type 2 diabetes: a multinational, 24-week, randomized, open-label, parallel-group comparison.

Robbins DC, Beisswenger PJ, Ceriello A, Goldberg RB, Moses RG, Pagkalos EM, Milicevic Z, Jones CA, Sarwat S, Tan MH.

Clin Ther. 2007 Nov;29(11):2349-64.PMID: 18158076 [PubMed - indexed for MEDLINE]Related articles

Randomized cross-over trial of insulin glargine plus lispro or NPH insulin plus regular human insulin in adolescents with type 1 diabetes on intensive insulin regimens.

Murphy NP, Keane SM, Ong KK, Ford-Adams M, Edge JA, Acerini CL, Dunger DB.

Diabetes Care. 2003 Mar;26(3):799-804.PMID: 12610040 [PubMed - indexed for MEDLINE]Related articlesFree article

Glargine is superior to neutral protamine Hagedorn for improving glycated haemoglobin and fasting blood glucose levels during intensive insulin therapy.

Fulcher GR, Gilbert RE, Yue DK.

Intern Med J. 2005 Sep;35(9):536-42.PMID: 16105155 [PubMed - indexed for MEDLINE]Related articles

Substitution of night-time continuous subcutaneous insulin infusion therapy for bedtime NPH insulin in a multiple injection regimen improves counterregulatory hormonal responses and warning symptoms of hypoglycaemia in IDDM.

Kanc K, Janssen MM, Keulen ET, Jacobs MA, Popp-Snijders C, Snoek FJ, Heine RJ.

Diabetologia. 1998 Mar;41(3):322-9.PMID: 9541173 [PubMed - indexed for MEDLINE]Related articles

Improved postprandial blood glucose control and reduced nocturnal hypoglycemia during treatment with two novel insulin lispro-protamine formulations, insulin lispro mix25 and insulin lispro mix50. Mix50 Study Group.

Roach P, Trautmann M, Arora V, Sun B, Anderson JH Jr.

Clin Ther. 1999 Mar;21(3):523-34.PMID: 10321421 [PubMed - indexed for MEDLINE]Related articles

Humalog Mix 25 in patients with type 2 diabetes which do not achieve acceptable glycemic control with oral agents: results from a phase III, randomized, parallel study.

Tîrgovişte CI, Străchinariu R, Farcaşiu E, Milicevic Z, Teodorescu G.

Rom J Intern Med. 2003;41(2):153-62.PMID: 15526500 [PubMed - indexed for MEDLINE]Related articles

Lispro or regular insulin for multiple injection therapy in adolescence. Differences in free insulin and glucose levels overnight.

Mohn A, Matyka KA, Harris DA, Ross KM, Edge JA, Dunger DB.

Diabetes Care. 1999 Jan;22(1):27-32.PMID: 10333899 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term intensive treatment of type 1 diabetes with the short-acting insulin analog lispro in variable combination with NPH insulin at mealtime.

Lalli C, Ciofetta M, Del Sindaco P, Torlone E, Pampanelli S, Compagnucci P, Cartechini MG, Bartocci L, Brunetti P, Bolli GB.

Diabetes Care. 1999 Mar;22(3):468-77.PMID: 10097931 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin detemir is associated with more predictable glycemic control and reduced risk of hypoglycemia than NPH insulin in patients with type 1 diabetes on a basal-bolus regimen with premeal insulin aspart.

Vague P, Selam JL, Skeie S, De Leeuw I, Elte JW, Haahr H, Kristensen A, Draeger E.

Diabetes Care. 2003 Mar;26(3):590-6.PMID: 12610006 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of the insulin analog lispro on nighttime blood glucose control in type 1 diabetic patients.

Ahmed AB, Home PD.

Diabetes Care. 1998 Jan;21(1):32-7.PMID: 9538967 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term efficacy and safety of insulin detemir compared to Neutral Protamine Hagedorn insulin in patients with Type 1 diabetes using a treat-to-target basal-bolus regimen with insulin aspart at meals: a 2-year, randomized, controlled trial.

Bartley PC, Bogoev M, Larsen J, Philotheou A.

Diabet Med. 2008 Apr;25(4):442-9.PMID: 18387078 [PubMed - indexed for MEDLINE]Related articlesFree article

Better long-term glycaemic control with the basal insulin glargine as compared with NPH in patients with Type 1 diabetes mellitus given meal-time lispro insulin.

Porcellati F, Rossetti P, Pampanelli S, Fanelli CG, Torlone E, Scionti L, Perriello G, Bolli GB.

Diabet Med. 2004 Nov;21(11):1213-20.PMID: 15498088 [PubMed - indexed for MEDLINE]Related articles