PubMed

Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p.

Mori Y, Otabe S, Dina C, Yasuda K, Populaire C, Lecoeur C, Vatin V, Durand E, Hara K, Okada T, Tobe K, Boutin P, Kadowaki T, Froguel P.

Diabetes. 2002 Apr;51(4):1247-55.PMID: 11916952 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs.

Ghosh S, Watanabe RM, Hauser ER, Valle T, Magnuson VL, Erdos MR, Langefeld CD, Balow J Jr, Ally DS, Kohtamaki K, Chines P, Birznieks G, Kaleta HS, Musick A, Te C, Tannenbaum J, Eldridge W, Shapiro S, Martin C, Witt A, So A, Chang J, Shurtleff B, Porter R, Kudelko K, Unni A, Segal L, Sharaf R, Blaschak-Harvan J, Eriksson J, Tenkula T, Vidgren G, Ehnholm C, Tuomilehto-Wolf E, Hagopian W, Buchanan TA, Tuomilehto J, Bergman RN, Collins FS, Boehnke M.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2198-203.PMID: 10051618 [PubMed - indexed for MEDLINE]Related articlesFree article

No evidence for linkage at candidate type 2 diabetes susceptibility loci on chromosomes 12 and 20 in United Kingdom Caucasians.

Frayling TM, McCarthy MI, Walker M, Levy JC, O'Rahilly S, Hitman GA, Rao PV, Bennett AJ, Jones EC, Menzel S, Ellard S, Hattersley AT.

J Clin Endocrinol Metab. 2000 Feb;85(2):853-7.PMID: 10690901 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24.

Vionnet N, Hani EH, Dupont S, Gallina S, Francke S, Dotte S, De Matos F, Durand E, Leprêtre F, Lecoeur C, Gallina P, Zekiri L, Dina C, Froguel P.

Am J Hum Genet. 2000 Dec;67(6):1470-80. Epub 2000 Nov 6.PMID: 11067779 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13-p12 in Japanese.

Nawata H, Shirasawa S, Nakashima N, Araki E, Hashiguchi J, Miyake S, Yamauchi T, Hamaguchi K, Yoshimatsu H, Takeda H, Fukushima H, Sasahara T, Yamaguchi K, Sonoda N, Sonoda T, Matsumoto M, Tanaka Y, Sugimoto H, Tsubouchi H, Inoguchi T, Yanase T, Wake N, Narazaki K, Eto T, Umeda F, Nakazaki M, Ono J, Asano T, Ito Y, Akazawa S, Hazegawa I, Takasu N, Shinohara M, Nishikawa T, Nagafuchi S, Okeda T, Eguchi K, Iwase M, Ishikawa M, Aoki M, Keicho N, Kato N, Yasuda K, Yamamoto K, Sasazuki T.

J Hum Genet. 2004;49(11):629-34. Epub 2004 Oct 14.PMID: 15490285 [PubMed - indexed for MEDLINE]Related articles

Exclusion of the hepatocyte nuclear factor 4alpha as a candidate gene for late-onset NIDDM linked with chromosome 20q.

Malecki MT, Antonellis A, Casey P, Ji L, Wantman M, Warram JH, Krolewski AS.

Diabetes. 1998 Jun;47(6):970-2. No abstract available. PMID: 9604877 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes.

Silander K, Mohlke KL, Scott LJ, Peck EC, Hollstein P, Skol AD, Jackson AU, Deloukas P, Hunt S, Stavrides G, Chines PS, Erdos MR, Narisu N, Conneely KN, Li C, Fingerlin TE, Dhanjal SK, Valle TT, Bergman RN, Tuomilehto J, Watanabe RM, Boehnke M, Collins FS.

Diabetes. 2004 Apr;53(4):1141-9.PMID: 15047633 [PubMed - indexed for MEDLINE]Related articlesFree article

A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.

Love-Gregory LD, Wasson J, Ma J, Jin CH, Glaser B, Suarez BK, Permutt MA.

Diabetes. 2004 Apr;53(4):1134-40.PMID: 15047632 [PubMed - indexed for MEDLINE]Related articlesFree article

A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14.

Silander K, Scott LJ, Valle TT, Mohlke KL, Stringham HM, Wiles KR, Duren WL, Doheny KF, Pugh EW, Chines P, Narisu N, White PP, Fingerlin TE, Jackson AU, Li C, Ghosh S, Magnuson VL, Colby K, Erdos MR, Hill JE, Hollstein P, Humphreys KM, Kasad RA, Lambert J, Lazaridis KN, Lin G, Morales-Mena A, Patzkowski K, Pfahl C, Porter R, Rha D, Segal L, Suh YD, Tovar J, Unni A, Welch C, Douglas JA, Epstein MP, Hauser ER, Hagopian W, Buchanan TA, Watanabe RM, Bergman RN, Tuomilehto J, Collins FS, Boehnke M.

Diabetes. 2004 Mar;53(3):821-9.PMID: 14988269 [PubMed - indexed for MEDLINE]Related articlesFree article

A German genome-wide linkage scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome 1p36.13 and a type 2 diabetes locus on chromosome 16p12.2.

Hoffmann K, Mattheisen M, Dahm S, Nürnberg P, Roe C, Johnson J, Cox NJ, Wichmann HE, Wienker TF, Schulze J, Schwarz PE, Lindner TH.

Diabetologia. 2007 Jul;50(7):1418-22. Epub 2007 Apr 27.PMID: 17464498 [PubMed - indexed for MEDLINE]Related articles

A genome scan for type 2 diabetes susceptibility loci in a genetically isolated population.

Permutt MA, Wasson JC, Suarez BK, Lin J, Thomas J, Meyer J, Lewitzky S, Rennich JS, Parker A, DuPrat L, Maruti S, Chayen S, Glaser B.

Diabetes. 2001 Mar;50(3):681-5.PMID: 11246891 [PubMed - indexed for MEDLINE]Related articlesFree article

A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene.

Zouali H, Hani EH, Philippi A, Vionnet N, Beckmann JS, Demenais F, Froguel P.

Hum Mol Genet. 1997 Sep;6(9):1401-8.PMID: 9285775 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27.

Francke S, Manraj M, Lacquemant C, Lecoeur C, Leprêtre F, Passa P, Hebe A, Corset L, Yan SL, Lahmidi S, Jankee S, Gunness TK, Ramjuttun US, Balgobin V, Dina C, Froguel P.

Hum Mol Genet. 2001 Nov 15;10(24):2751-65.PMID: 11734540 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide scan for type 1 diabetic nephropathy in the Finnish population reveals suggestive linkage to a single locus on chromosome 3q.

Osterholm AM, He B, Pitkaniemi J, Albinsson L, Berg T, Sarti C, Tuomilehto J, Tryggvason K.

Kidney Int. 2007 Jan;71(2):140-5. Epub 2006 Oct 4.PMID: 17021601 [PubMed - indexed for MEDLINE]Related articles

Examination of candidate chromosomal regions for type 2 diabetes reveals a susceptibility locus on human chromosome 8p23.1.

Pezzolesi MG, Nam M, Nagase T, Klupa T, Dunn JS, Mlynarski WM, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2004 Feb;53(2):486-91.PMID: 14747302 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte nuclear factor-4alpha P2 promoter haplotypes are associated with type 2 diabetes in the Japanese population.

Hara K, Horikoshi M, Kitazato H, Ito C, Noda M, Ohashi J, Froguel P, Tokunaga K, Tobe K, Nagai R, Kadowaki T.

Diabetes. 2006 May;55(5):1260-4.PMID: 16644680 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic modifiers of the age at diagnosis of diabetes (MODY3) in carriers of hepatocyte nuclear factor-1alpha mutations map to chromosomes 5p15, 9q22, and 14q24.

Kim SH, Ma X, Klupa T, Powers C, Pezzolesi M, Warram JH, Rich SS, Krolewski AS, Doria A.

Diabetes. 2003 Aug;52(8):2182-6.PMID: 12882939 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of new mutations in the hepatocyte nuclear factor 4alpha gene among families with early onset Type 2 diabetes mellitus.

Malecki MT, Yang Y, Antonellis A, Curtis S, Warram JH, Krolewski AS.

Diabet Med. 1999 Mar;16(3):193-200.PMID: 10227563 [PubMed - indexed for MEDLINE]Related articles

Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population.

Weedon MN, Owen KR, Shields B, Hitman G, Walker M, McCarthy MI, Love-Gregory LD, Permutt MA, Hattersley AT, Frayling TM.

Diabetes. 2004 Nov;53(11):3002-6.PMID: 15504983 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide scan in 124 Indonesian sib-pair families with schizophrenia reveals genome-wide significant linkage to a locus on chromosome 3p26-21.

Irmansyah, Schwab SG; Heriani, Handoko HY, Kusumawardhani A, Widyawati I, Amir N, Nasrun MW, Holmans P, Knapp M, Wildenauer DB.

Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 5;147B(7):1245-52.PMID: 18449910 [PubMed - indexed for MEDLINE]Related articles