PubMed

Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation.

James LR, Tang D, Ingram A, Ly H, Thai K, Cai L, Scholey JW.

Diabetes. 2002 Apr;51(4):1146-56.PMID: 11916938 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of GFAT activates PAI-1 promoter in mesangial cells.

James LR, Fantus IG, Goldberg H, Ly H, Scholey JW.

Am J Physiol Renal Physiol. 2000 Oct;279(4):F718-27.PMID: 10997922 [PubMed - indexed for MEDLINE]Related articlesFree article

Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance.

Marshall S, Bacote V, Traxinger RR.

J Biol Chem. 1991 Mar 15;266(8):4706-12.PMID: 2002019 [PubMed - indexed for MEDLINE]Related articlesFree article

P38 mitogen-activated protein kinase mediates hexosamine-induced TGFbeta1 mRNA expression in human mesangial cells.

Burt DJ, Gruden G, Thomas SM, Tutt P, Dell'Anna C, Viberti GC, Gnudi L.

Diabetologia. 2003 Apr;46(4):531-7. Epub 2003 Apr 5.PMID: 12679868 [PubMed - indexed for MEDLINE]Related articles

Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo.

Clerk LH, Rattigan S, Clark MG.

Diabetes. 2002 Apr;51(4):1138-45.PMID: 11916937 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance in multiple insulin sensitive tissues.

Virkamäki A, Daniels MC, Hämäläinen S, Utriainen T, McClain D, Yki-Järvinen H.

Endocrinology. 1997 Jun;138(6):2501-7.PMID: 9165041 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) and glucosamine treatment on translocation of GLUT4 in rat adipose cells.

Chen H, Ing BL, Robinson KA, Feagin AC, Buse MG, Quon MJ.

Mol Cell Endocrinol. 1997 Nov 30;135(1):67-77.PMID: 9453242 [PubMed - indexed for MEDLINE]Related articles

Coordinated regulation of glutamine:fructose-6-phosphate amidotransferase activity by insulin, glucose, and glutamine. Role of hexosamine biosynthesis in enzyme regulation.

Traxinger RR, Marshall S.

J Biol Chem. 1991 Jun 5;266(16):10148-54.PMID: 2037571 [PubMed - indexed for MEDLINE]Related articlesFree article

Upstream stimulatory factor (USF) proteins induce human TGF-beta1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: up-regulation of USF activity by the hexosamine biosynthetic pathway.

Weigert C, Brodbeck K, Sawadogo M, Häring HU, Schleicher ED.

J Biol Chem. 2004 Apr 16;279(16):15908-15. Epub 2004 Feb 2.PMID: 14757763 [PubMed - indexed for MEDLINE]Related articlesFree article

Complete inhibition of glucose-induced desensitization of the glucose transport system by inhibitors of mRNA synthesis. Evidence for rapid turnover of glutamine:fructose-6-phosphate amidotransferase.

Marshall S, Bacote V, Traxinger RR.

J Biol Chem. 1991 Jun 5;266(16):10155-61.PMID: 2037572 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the hexosamine biosynthetic pathway in diabetic nephropathy.

Schleicher ED, Weigert C.

Kidney Int Suppl. 2000 Sep;77:S13-8. Review.PMID: 10997685 [PubMed - indexed for MEDLINE]Related articles

INFLUENCE OF GLUCOSAMINE ON GLOMERULAR MESEANGIAL CELL TURNOVER: IMPLICATIONS FOR HYPERGLYCEMIA AND HEXOSAMINE PATHWAY FLUX.

James LR, Le C, Scholey JW.

Am J Physiol Endocrinol Metab. 2009 Nov 10. [Epub ahead of print]PMID: 19903862 [PubMed - as supplied by publisher]Related articles

Differential effects of GLUT1 or GLUT4 overexpression on hexosamine biosynthesis by muscles of transgenic mice.

Buse MG, Robinson KA, Marshall BA, Mueckler M.

J Biol Chem. 1996 Sep 20;271(38):23197-202.PMID: 8798515 [PubMed - indexed for MEDLINE]Related articlesFree article

Local activation of the IkappaK-NF-kappaB pathway in muscle does not cause insulin resistance.

Polkinghorne E, Lau Q, Cooney GJ, Kraegen EW, Cleasby ME.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E316-25. Epub 2007 Nov 20.PMID: 18029440 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-alpha.

Youd JM, Rattigan S, Clark MG.

Diabetes. 2000 Nov;49(11):1904-9.PMID: 11078458 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucosamine activates the plasminogen activator inhibitor 1 gene promoter through Sp1 DNA binding sites in glomerular mesangial cells.

Goldberg HJ, Scholey J, Fantus IG.

Diabetes. 2000 May;49(5):863-71.PMID: 10905498 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased activity of the hexosamine synthesis pathway in muscles of insulin-resistant ob/ob mice.

Buse MG, Robinson KA, Gettys TW, McMahon EG, Gulve EA.

Am J Physiol. 1997 Jun;272(6 Pt 1):E1080-8.PMID: 9227455 [PubMed - indexed for MEDLINE]Related articles

Glucose regulation of transforming growth factor-alpha expression is mediated by products of the hexosamine biosynthesis pathway.

Daniels MC, Kansal P, Smith TM, Paterson AJ, Kudlow JE, McClain DA.

Mol Endocrinol. 1993 Aug;7(8):1041-8.PMID: 8232303 [PubMed - indexed for MEDLINE]Related articles

Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.

Hazel M, Cooksey RC, Jones D, Parker G, Neidigh JL, Witherbee B, Gulve EA, McClain DA.

Endocrinology. 2004 May;145(5):2118-28. Epub 2003 Dec 18.PMID: 14684615 [PubMed - indexed for MEDLINE]Related articlesFree article

The hexosamine biosynthetic pathway and glucose-induced down regulation of glucose transport in L6 myotubes.

Davidson MB, Hunt K, Fernandez-Mejia C.

Biochim Biophys Acta. 1994 Sep 28;1201(1):113-7.PMID: 7918574 [PubMed - indexed for MEDLINE]Related articles