PubMed

Indinavir induces acute and reversible peripheral insulin resistance in rats.

Hruz PW, Murata H, Qiu H, Mueckler M.

Diabetes. 2002 Apr;51(4):937-42.PMID: 11916910 [PubMed - indexed for MEDLINE]Related articlesFree article

The HIV protease inhibitor indinavir decreases insulin- and contraction-stimulated glucose transport in skeletal muscle.

Nolte LA, Yarasheski KE, Kawanaka K, Fisher J, Le N, Holloszy JO.

Diabetes. 2001 Jun;50(6):1397-401.PMID: 11375341 [PubMed - indexed for MEDLINE]Related articlesFree article

The mechanism of insulin resistance caused by HIV protease inhibitor therapy.

Murata H, Hruz PW, Mueckler M.

J Biol Chem. 2000 Jul 7;275(27):20251-4.PMID: 10806189 [PubMed - indexed for MEDLINE]Related articlesFree article

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity.

Hertel J, Struthers H, Horj CB, Hruz PW.

J Biol Chem. 2004 Dec 31;279(53):55147-52. Epub 2004 Oct 20.PMID: 15496402 [PubMed - indexed for MEDLINE]Related articlesFree article

Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations.

Murata H, Hruz PW, Mueckler M.

AIDS. 2002 Apr 12;16(6):859-63.PMID: 11919487 [PubMed - indexed for MEDLINE]Related articles

Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study.

Noor MA, Seneviratne T, Aweeka FT, Lo JC, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C.

AIDS. 2002 Mar 29;16(5):F1-8.PMID: 11964551 [PubMed - indexed for MEDLINE]Related articles

In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator.

Cheng M, Chen S, Schow SR, Manchem VP, Spevak WR, Cristobal CP, Shi S, Macsata RW, Lum RT, Goldfine ID, Keck JG.

J Cell Biochem. 2004 Aug 15;92(6):1234-45.PMID: 15258906 [PubMed - indexed for MEDLINE]Related articles

HIV-protease inhibitors induce expression of suppressor of cytokine signaling-1 in insulin-sensitive tissues and promote insulin resistance and type 2 diabetes mellitus.

Carper MJ, Cade WT, Cam M, Zhang S, Shalev A, Yarasheski KE, Ramanadham S.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E558-67. Epub 2008 Jan 2.PMID: 18171911 [PubMed - indexed for MEDLINE]Related articlesFree article

Time courses of changes in hepatic and skeletal muscle insulin action and GLUT4 protein in skeletal muscle after STZ injection.

Youn JH, Kim JK, Buchanan TA.

Diabetes. 1994 Apr;43(4):564-71.PMID: 8138062 [PubMed - indexed for MEDLINE]Related articles

HIV protease inhibitors acutely impair glucose-stimulated insulin release.

Koster JC, Remedi MS, Qiu H, Nichols CG, Hruz PW.

Diabetes. 2003 Jul;52(7):1695-700.PMID: 12829635 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin sensitivity is preserved despite disrupted endothelial function.

Shankar SS, Considine RV, Gorski JC, Steinberg HO.

Am J Physiol Endocrinol Metab. 2006 Oct;291(4):E691-6. Epub 2006 May 16.PMID: 16705064 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic effects of indinavir in healthy HIV-seronegative men.

Noor MA, Lo JC, Mulligan K, Schwarz JM, Halvorsen RA, Schambelan M, Grunfeld C.

AIDS. 2001 May 4;15(7):F11-8.PMID: 11399973 [PubMed - indexed for MEDLINE]Related articles

Indinavir uncovers different contributions of GLUT4 and GLUT1 towards glucose uptake in muscle and fat cells and tissues.

Rudich A, Konrad D, Török D, Ben-Romano R, Huang C, Niu W, Garg RR, Wijesekara N, Germinario RJ, Bilan PJ, Klip A.

Diabetologia. 2003 May;46(5):649-58. Epub 2003 Apr 24.PMID: 12712244 [PubMed - indexed for MEDLINE]Related articles

Direct comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal.

Yan Q, Hruz PW.

J Acquir Immune Defic Syndr. 2005 Dec 1;40(4):398-403.PMID: 16280693 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective angiotensin II receptor receptor antagonism reduces insulin resistance in obese Zucker rats.

Henriksen EJ, Jacob S, Kinnick TR, Teachey MK, Krekler M.

Hypertension. 2001 Oct;38(4):884-90.PMID: 11641303 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome.

Buhl ES, Jessen N, Pold R, Ledet T, Flyvbjerg A, Pedersen SB, Pedersen O, Schmitz O, Lund S.

Diabetes. 2002 Jul;51(7):2199-206.PMID: 12086950 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute effect of growth hormone to induce peripheral insulin resistance is independent of FFA and insulin levels in rats.

Kim JK, Choi CS, Youn JH.

Am J Physiol. 1999 Oct;277(4 Pt 1):E742-9.PMID: 10516135 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of non-esterified fatty acid oxidation in glucocorticoid-induced peripheral insulin resistance in vivo in rats.

Guillaume-Gentil C, Assimacopoulos-Jeannet F, Jeanrenaud B.

Diabetologia. 1993 Oct;36(10):899-906.PMID: 8243867 [PubMed - indexed for MEDLINE]Related articles

Chronic ethanol feeding impairs glucose tolerance but does not produce skeletal muscle insulin resistance in rat epitrochlearis muscle.

Wilkes JJ, Nagy LE.

Alcohol Clin Exp Res. 1996 Sep;20(6):1016-22.PMID: 8892521 [PubMed - indexed for MEDLINE]Related articles

Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle.

Carvalho E, Kotani K, Peroni OD, Kahn BB.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E551-61. Epub 2005 May 31.PMID: 15928024 [PubMed - indexed for MEDLINE]Related articlesFree article