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The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity.
Gaster M, Petersen I, Højlund K, Poulsen P, Beck-Nielsen H.
Diabetes. 2002 Apr;51(4):921-7.PMID: 11916908 [PubMed - indexed for MEDLINE]Related articlesFree article
Regulation of glycogen synthase activity in cultured skeletal muscle cells from subjects with type II diabetes: role of chronic hyperinsulinemia and hyperglycemia.
Nikoulina SE, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Park KS, Henry RR.
Diabetes. 1997 Jun;46(6):1017-24.PMID: 9166674 [PubMed - indexed for MEDLINE]Related articles
Studies of gene expression and activity of hexokinase, phosphofructokinase and glycogen synthase in human skeletal muscle in states of altered insulin-stimulated glucose metabolism.
Vestergaard H.
Dan Med Bull. 1999 Feb;46(1):13-34. Review.PMID: 10081651 [PubMed - indexed for MEDLINE]Related articles
Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures.
Henry RR, Abrams L, Nikoulina S, Ciaraldi TP.
Diabetes. 1995 Aug;44(8):936-46.PMID: 7622000 [PubMed - indexed for MEDLINE]Related articles
Glucosamine regulation of glucose metabolism in cultured human skeletal muscle cells: divergent effects on glucose transport/phosphorylation and glycogen synthase in non-diabetic and type 2 diabetic subjects.
Ciaraldi TP, Carter L, Nikoulina S, Mudaliar S, McClain DA, Henry RR.
Endocrinology. 1999 Sep;140(9):3971-80.PMID: 10465266 [PubMed - indexed for MEDLINE]Related articlesFree article
The primary defect in glycogen synthase activity is not based on increased glycogen synthase kinase-3alpha activity in diabetic myotubes.
Gaster M, Brusgaard K, Handberg A, Højlund K, Wojtaszewski JF, Beck-Nielsen H.
Biochem Biophys Res Commun. 2004 Jul 9;319(4):1235-40.PMID: 15194499 [PubMed - indexed for MEDLINE]Related articles
Acquired defects of glycogen synthase activity in cultured human skeletal muscle cells: influence of high glucose and insulin levels.
Henry RR, Ciaraldi TP, Mudaliar S, Abrams L, Nikoulina SE.
Diabetes. 1996 Apr;45(4):400-7.PMID: 8603759 [PubMed - indexed for MEDLINE]Related articles
Troglitazone regulation of glucose metabolism in human skeletal muscle cultures from obese type II diabetic subjects.
Park KS, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Nikoulina SE, Henry RR.
J Clin Endocrinol Metab. 1998 May;83(5):1636-43.PMID: 9589670 [PubMed - indexed for MEDLINE]Related articlesFree article
Insulin signalling in skeletal muscle of subjects with or without Type II-diabetes and first degree relatives of patients with the disease.
Meyer MM, Levin K, Grimmsmann T, Beck-Nielsen H, Klein HH.
Diabetologia. 2002 Jun;45(6):813-22. Epub 2002 May 8.PMID: 12107725 [PubMed - indexed for MEDLINE]Related articles
Hyperglycaemia compensates for the defects in insulin-mediated glucose metabolism and in the activation of glycogen synthase in the skeletal muscle of patients with type 2 (non-insulin-dependent) diabetes mellitus.
Vaag A, Damsbo P, Hother-Nielsen O, Beck-Nielsen H.
Diabetologia. 1992 Jan;35(1):80-8.PMID: 1541385 [PubMed - indexed for MEDLINE]Related articles
Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms.
Henry RR, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Park KS, Nikoulina SE.
J Clin Invest. 1996 Sep 1;98(5):1231-6.PMID: 8787686 [PubMed - indexed for MEDLINE]Related articlesFree article
Relationship of skeletal muscle glucose 6-phosphate to glucose disposal rate and glycogen synthase activity in insulin-resistant and non-insulin-dependent diabetic rhesus monkeys.
Ortmeyer HK, Bodkin NL, Hansen BC.
Diabetologia. 1994 Feb;37(2):127-33.PMID: 8163045 [PubMed - indexed for MEDLINE]Related articles
Exercise training increases glycogen synthase activity and GLUT4 expression but not insulin signaling in overweight nondiabetic and type 2 diabetic subjects.
Christ-Roberts CY, Pratipanawatr T, Pratipanawatr W, Berria R, Belfort R, Kashyap S, Mandarino LJ.
Metabolism. 2004 Sep;53(9):1233-42.PMID: 15334390 [PubMed - indexed for MEDLINE]Related articles
Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes.
Højlund K, Staehr P, Hansen BF, Green KA, Hardie DG, Richter EA, Beck-Nielsen H, Wojtaszewski JF.
Diabetes. 2003 Jun;52(6):1393-402.PMID: 12765949 [PubMed - indexed for MEDLINE]Related articlesFree article
Insulin receptor function and glycogen synthase activity in human skeletal muscle. Physiology and pathophysiology.
Bak JF.
Dan Med Bull. 1994 Apr;41(2):179-92. Review.PMID: 8039433 [PubMed - indexed for MEDLINE]Related articles
Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus.
Damsbo P, Vaag A, Hother-Nielsen O, Beck-Nielsen H.
Diabetologia. 1991 Apr;34(4):239-45.PMID: 1906024 [PubMed - indexed for MEDLINE]Related articles
The reduced insulin-mediated glucose oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin--evidence from cultured myotubes.
Gaster M, Beck-Nielsen H.
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Effects of tumor necrosis factor-alpha on glucose metabolism in cultured human muscle cells from nondiabetic and type 2 diabetic subjects.
Ciaraldi TP, Carter L, Mudaliar S, Kern PA, Henry RR.
Endocrinology. 1998 Dec;139(12):4793-800.PMID: 9832415 [PubMed - indexed for MEDLINE]Related articlesFree article
Insulin unexpectedly increases the glucose 6-phosphate Ka of skeletal muscle glycogen synthase in calorie-restricted monkeys.
Ortmeyer HK, Huang L, Larner J, Hansen BC.
J Basic Clin Physiol Pharmacol. 1998;9(2-4):309-23.PMID: 10212841 [PubMed - indexed for MEDLINE]Related articles
A thiazolidinedione improves in vivo insulin action on skeletal muscle glycogen synthase in insulin-resistant monkeys.
Ortmeyer HK, Bodkin NL, Haney J, Yoshioka S, Horikoshi H, Hansen BC.
Int J Exp Diabetes Res. 2000;1(3):195-202.PMID: 11467410 [PubMed - indexed for MEDLINE]Related articlesFree article
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