PubMed

Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor.

Mentuccia D, Proietti-Pannunzi L, Tanner K, Bacci V, Pollin TI, Poehlman ET, Shuldiner AR, Celi FS.

Diabetes. 2002 Mar;51(3):880-3.PMID: 11872697 [PubMed - indexed for MEDLINE]Related articlesFree article

The Thr92Ala deiodinase type 2 (DIO2) variant is not associated with type 2 diabetes or indices of insulin resistance in the old order of Amish.

Mentuccia D, Thomas MJ, Coppotelli G, Reinhart LJ, Mitchell BD, Shuldiner AR, Celi FS.

Thyroid. 2005 Nov;15(11):1223-7.PMID: 16356084 [PubMed - indexed for MEDLINE]Related articles

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.

Grarup N, Andersen MK, Andreasen CH, Albrechtsen A, Borch-Johnsen K, Jørgensen T, Auwerx J, Schmitz O, Hansen T, Pedersen O.

J Clin Endocrinol Metab. 2007 Jan;92(1):363-6. Epub 2006 Oct 31.PMID: 17077128 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg beta3-adrenoceptor gene variant.

Tchernof A, Starling RD, Turner A, Shuldiner AR, Walston JD, Silver K, Poehlman ET.

Diabetes. 2000 Oct;49(10):1709-13.PMID: 11016455 [PubMed - indexed for MEDLINE]Related articlesFree article

Tryptophan 64 --> arginine polymorphism of beta-3-adrenergic receptor in Chilean women with polycystic ovary syndrome.

Pérez-Bravo F, Echiburú B, Maliqueo M, Santos JL, Sir-Petermann T.

Clin Endocrinol (Oxf). 2005 Feb;62(2):126-31.PMID: 15670186 [PubMed - indexed for MEDLINE]Related articles

Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns.

Widén E, Lehto M, Kanninen T, Walston J, Shuldiner AR, Groop LC.

N Engl J Med. 1995 Aug 10;333(6):348-51.PMID: 7609751 [PubMed - indexed for MEDLINE]Related articlesFree article

[Effects of Trp64Arg mutation in the beta 3-adrenergic receptor gene on body fat, plasma glucose level, lipid profile, insulin secretion and action in Chinese]

Xiang K, Jia W, Lu H, Zheng T, Lu J, Tang J, Ding W, Sun D, Li J.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 1998 Dec 10;15(6):337-40. Chinese. PMID: 9845761 [PubMed - indexed for MEDLINE]Related articles

Comparison of body fat distribution and blood lipid profiles according to Trp64Arg polymorphism for the beta 3-adrenergic receptor gene in Korean middle-aged women.

Kim K, Lee S, Lee S, Lim K, Cheun W, Ahn N, Shin Y, Park J, Hong C, Kim S.

J Nutr Sci Vitaminol (Tokyo). 2006 Aug;52(4):281-6.PMID: 17087055 [PubMed - indexed for MEDLINE]Related articlesFree article

TRP64ARG beta 3-adrenergic receptor and obesity in Mexican Americans.

Silver K, Mitchell BD, Walston J, Sorkin JD, Stern MP, Roth J, Shuldiner AR.

Hum Genet. 1997 Dec;101(3):306-11.PMID: 9439659 [PubMed - indexed for MEDLINE]Related articles

Trp64Arg variant of the beta3-adrenoceptor and insulin resistance in obese postmenopausal women.

García-Rubi E, Starling RD, Tchernof A, Matthews DE, Walston JD, Shuldiner AR, Silver K, Poehlman ET, Calles-Escandón J.

J Clin Endocrinol Metab. 1998 Nov;83(11):4002-5.PMID: 9814483 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta(3)-adrenergic receptor gene variant is associated with upper body obesity only in obese Japanese-American men but not in women.

Kawamura T, Egusa G, Fujikawa R, Okubo M.

Diabetes Res Clin Pract. 2001 Oct;54(1):49-55.PMID: 11532330 [PubMed - indexed for MEDLINE]Related articles

[Mutation in the beta3-adrenergic receptor gene (Trp64Arg) does not influence insulin resistence, energy metabolism, fat distribution and lipid spectrum in young people. Pilot study]

Bendlová B, Mazura I, Vcelák J, Pelikánová T, Kunesová M, Hainer V, Obenberger J, Palyzová D.

Vnitr Lek. 1999 May;45(5):267-72. Czech. PMID: 15641247 [PubMed - indexed for MEDLINE]Related articles

No effect of the Trp64Arg beta(3)-adrenoceptor gene variant on weight loss, body composition, or energy expenditure in obese, caucasian postmenopausal women.

Rawson ES, Nolan A, Silver K, Shuldiner AR, Poehlman ET.

Metabolism. 2002 Jun;51(6):801-5.PMID: 12037740 [PubMed - indexed for MEDLINE]Related articles

The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals.

Kurokawa N, Young EH, Oka Y, Satoh H, Wareham NJ, Sandhu MS, Loos RJ.

Int J Obes (Lond). 2008 Aug;32(8):1240-9. Epub 2008 Jun 24. Review.PMID: 18574485 [PubMed - indexed for MEDLINE]Related articles

Association of beta3-adrenergic receptor gene polymorphism with insulin resistance in Japanese-American men.

Kawamura T, Egusa G, Okubo M, Imazu M, Yamakido M.

Metabolism. 1999 Nov;48(11):1367-70.PMID: 10582543 [PubMed - indexed for MEDLINE]Related articles

Association of Trp64Arg polymorphism of beta3-adrenergic receptor with insulin resistance in Polish children with obesity.

Zawodniak-Szałapska M, Stawerska R, Brzeziańska E, Pastuszak-Lewandoska D, Lukamowicz J, Cypryk K, Lewiński A.

J Pediatr Endocrinol Metab. 2008 Feb;21(2):147-54.PMID: 18422027 [PubMed - indexed for MEDLINE]Related articles

[A prospective study of the relationship between Trp64Arg beta(3)-adrenergic receptor gene polymorphism and metabolic syndrome]

Zhu LY, Hu LY, Li XL.

Zhonghua Nei Ke Za Zhi. 2008 Oct;47(10):811-4. Chinese. PMID: 19080138 [PubMed - indexed for MEDLINE]Related articles

Relation of Trp64Arg polymorphism of beta 3-adrenergic receptor gene to adipocytokines and fat distribution in obese patients.

de Luis DA, Aller R, Izaola O, Gonzalez Sagrado M, Conde R.

Ann Nutr Metab. 2008;52(4):267-71. Epub 2008 Jul 10.PMID: 18617734 [PubMed - indexed for MEDLINE]Related articles

The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus.

Canani LH, Capp C, Dora JM, Meyer EL, Wagner MS, Harney JW, Larsen PR, Gross JL, Bianco AC, Maia AL.

J Clin Endocrinol Metab. 2005 Jun;90(6):3472-8. Epub 2005 Mar 29.PMID: 15797963 [PubMed - indexed for MEDLINE]Related articlesFree article

Energy expenditure, body composition and insulin response to glucose in male twins discordant for the Trp64Arg polymorphism of the beta3-adrenergic receptor gene.

Højlund K, Christiansen C, Bjørnsbo KS, Poulsen P, Bathum L, Henriksen JE, Lammert O, Beck-Nielsen H.

Diabetes Obes Metab. 2006 May;8(3):322-30.PMID: 16634992 [PubMed - indexed for MEDLINE]Related articles