PubMed

Unprocessed proinsulin promotes cell survival during neurulation in the chick embryo.

Hernández-Sánchez C, Rubio E, Serna J, de la Rosa EJ, de Pablo F.

Diabetes. 2002 Mar;51(3):770-7.PMID: 11872678 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of prepancreatic (pro)insulin and the insulin receptor in prevention of embryonic apoptosis.

Morales AV, Serna J, Alarcón C, de la Rosa EJ, de Pablo F.

Endocrinology. 1997 Sep;138(9):3967-75.PMID: 9275088 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmentally regulated expression of the preproinsulin gene in the chicken embryo during gastrulation and neurulation.

Pérez-Villamil B, de la Rosa EJ, Morales AV, de Pablo F.

Endocrinology. 1994 Dec;135(6):2342-50.PMID: 7988416 [PubMed - indexed for MEDLINE]Related articles

Synthesis and differentially regulated processing of proinsulin in developing chick pancreas, liver and neuroretina.

Alarcón C, Serna J, Pérez-Villamil B, de Pablo F.

FEBS Lett. 1998 Oct 9;436(3):361-6.PMID: 9801149 [PubMed - indexed for MEDLINE]Related articles

In vivo regulation of cell death by embryonic (pro)insulin and the insulin receptor during early retinal neurogenesis.

Díaz B, Serna J, De Pablo F, de la Rosa EJ.

Development. 2000 Apr;127(8):1641-9.PMID: 10725240 [PubMed - indexed for MEDLINE]Related articlesFree article

Determination of the genomic structures of two nonallelic preproinsulin genes in Xenopus laevis using the polymerase chain reaction.

Shuldiner AR, Nirula A, Scott LA.

Gen Comp Endocrinol. 1995 Feb;97(2):220-30.PMID: 7542614 [PubMed - indexed for MEDLINE]Related articles

Insulin gene expression in chicken ontogeny: pancreatic, extrapancreatic, and prepancreatic.

Serrano J, Bevins CL, Young SW, de Pablo F.

Dev Biol. 1989 Apr;132(2):410-8.PMID: 2647543 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin.

Wicksteed B, Alarcon C, Briaud I, Lingohr MK, Rhodes CJ.

J Biol Chem. 2003 Oct 24;278(43):42080-90. Epub 2003 Aug 18.PMID: 12928442 [PubMed - indexed for MEDLINE]Related articlesFree article

(Pro)insulin and insulin-like growth factor I complementary expression and roles in early development.

Alarcón C, Morales AV, Pimentel B, Serna J, de Pablo F.

Comp Biochem Physiol B Biochem Mol Biol. 1998 Sep;121(1):13-7. Review.PMID: 9972280 [PubMed - indexed for MEDLINE]Related articles

Modulation of the chaperone heat shock cognate 70 by embryonic (pro)insulin correlates with prevention of apoptosis.

de la Rosa EJ, Vega-Núñez E, Morales AV, Serna J, Rubio E, de Pablo F.

Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9950-5.PMID: 9707581 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmental regulation of a proinsulin messenger RNA generated by intron retention.

Mansilla A, López-Sánchez C, de la Rosa EJ, García-Martínez V, Martínez-Salas E, de Pablo F, Hernández-Sánchez C.

EMBO Rep. 2005 Dec;6(12):1182-7.PMID: 16179943 [PubMed - indexed for MEDLINE]Related articlesFree article

Autocrine/paracrine role of insulin-related growth factors in neurogenesis: local expression and effects on cell proliferation and differentiation in retina.

Hernández-Sánchez C, López-Carranza A, Alarcón C, de La Rosa EJ, de Pablo F.

Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9834-8.PMID: 7568228 [PubMed - indexed for MEDLINE]Related articlesFree article

Upstream AUGs in embryonic proinsulin mRNA control its low translation level.

Hernández-Sánchez C, Mansilla A, de la Rosa EJ, Pollerberg GE, Martínez-Salas E, de Pablo F.

EMBO J. 2003 Oct 15;22(20):5582-92.PMID: 14532130 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of the two nonallelic proinsulin genes in the developing mouse embryo.

Deltour L, Leduque P, Blume N, Madsen O, Dubois P, Jami J, Bucchini D.

Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):527-31.PMID: 8421685 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinsulin in development: New roles for an ancient prohormone.

Hernández-Sánchez C, Mansilla A, de la Rosa EJ, de Pablo F.

Diabetologia. 2006 Jun;49(6):1142-50. Epub 2006 Apr 5. Review.PMID: 16596360 [PubMed - indexed for MEDLINE]Related articles

Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing.

Da Silva Xavier G, Qian Q, Cullen PJ, Rutter GA.

Biochem J. 2004 Jan 1;377(Pt 1):149-58. Erratum in: Biochem J. 2004 Nov 1;383(Pt. 3):599. PMID: 14563207 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptotic cell death of proliferating neuroepithelial cells in the embryonic retina is prevented by insulin.

Díaz B, Pimentel B, de Pablo F, de La Rosa EJ.

Eur J Neurosci. 1999 May;11(5):1624-32.PMID: 10215915 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial regulation of insulin production in rat pancreatic islets.

Leibowitz G, Khaldi MZ, Shauer A, Parnes M, Oprescu AI, Cerasi E, Jonas JC, Kaiser N.

Diabetologia. 2005 Aug;48(8):1549-59. Epub 2005 Jun 29.PMID: 15986240 [PubMed - indexed for MEDLINE]Related articles

Insulin and insulin-like growth factor I both stimulate metabolism, growth, and differentiation in the postneurula chick embryo.

Girbau M, Gomez JA, Lesniak MA, de Pablo F.

Endocrinology. 1987 Oct;121(4):1477-82.PMID: 3308439 [PubMed - indexed for MEDLINE]Related articles

Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level.

Alarcon C, Wicksteed B, Rhodes CJ.

Diabetologia. 2006 Dec;49(12):2920-9. Epub 2006 Oct 20.PMID: 17053883 [PubMed - indexed for MEDLINE]Related articles