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    Results: 1 to 20 of 466

    1.

    NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1.

    Lawrence MC, Bhatt HS, Easom RA.

    Diabetes. 2002 Mar;51(3):691-8.PMID: 11872668 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element.

    Skoglund G, Hussain MA, Holz GG.

    Diabetes. 2000 Jul;49(7):1156-64.PMID: 10909973 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Synergistic effect of dimethyl sulfoxide on glucagon-like peptide 1 (GLP-1)-stimulated insulin secretion and gene transcription in INS-1 cells: characterization and implications.

    Kemp DM, Habener JF.

    Biochem Pharmacol. 2002 Aug 15;64(4):689-97.PMID: 12167488 [PubMed - indexed for MEDLINE]Related articles

    4.

    Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism.

    Wang X, Zhou J, Doyle ME, Egan JM.

    Endocrinology. 2001 May;142(5):1820-7.PMID: 11316746 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Regulation of insulin gene transcription by a Ca(2+)-responsive pathway involving calcineurin and nuclear factor of activated T cells.

    Lawrence MC, Bhatt HS, Watterson JM, Easom RA.

    Mol Endocrinol. 2001 Oct;15(10):1758-67.PMID: 11579208 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathway.

    Jimenez-Feltstrom J, Lundquist I, Salehi A.

    Cell Tissue Res. 2005 Feb;319(2):221-30. Epub 2004 Nov 19.PMID: 15558323 [PubMed - indexed for MEDLINE]Related articles

    7.

    Insulinotropic hormone glucagon-like peptide 1 (GLP-1) activation of insulin gene promoter inhibited by p38 mitogen-activated protein kinase.

    Kemp DM, Habener JF.

    Endocrinology. 2001 Mar;142(3):1179-87.PMID: 11181533 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Glucagon-like peptide-1 induces a cAMP-dependent increase of [Na+]i associated with insulin secretion in pancreatic beta-cells.

    Miura Y, Matsui H.

    Am J Physiol Endocrinol Metab. 2003 Nov;285(5):E1001-9.PMID: 14534075 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Glucagon-like peptide 1 elevates cytosolic calcium in pancreatic beta-cells independently of protein kinase A.

    Bode HP, Moormann B, Dabew R, Göke B.

    Endocrinology. 1999 Sep;140(9):3919-27.PMID: 10465260 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation.

    Chepurny OG, Holz GG.

    Cell Tissue Res. 2002 Feb;307(2):191-201. Epub 2002 Jan 8.PMID: 11845326 [PubMed - indexed for MEDLINE]Related articles

    11.

    Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.

    Friedrichsen BN, Neubauer N, Lee YC, Gram VK, Blume N, Petersen JS, Nielsen JH, Møldrup A.

    J Endocrinol. 2006 Mar;188(3):481-92.PMID: 16522728 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells.

    Tsuboi T, da Silva Xavier G, Holz GG, Jouaville LS, Thomas AP, Rutter GA.

    Biochem J. 2003 Jan 15;369(Pt 2):287-99.PMID: 12410638 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Transfection of pancreatic-derived beta-cells with a minigene encoding for human glucagon-like peptide-1 regulates glucose-dependent insulin synthesis and secretion.

    Hui H, Yu R, Bousquet C, Perfetti R.

    Endocrinology. 2002 Sep;143(9):3529-39. Erratum in: Endocrinology 2002 Nov;143(11):4349. PMID: 12193567 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Glucagon-like peptide-1 stimulates human insulin promoter activity in part through cAMP-responsive elements that lie upstream and downstream of the transcription start site.

    Hay CW, Sinclair EM, Bermano G, Durward E, Tadayyon M, Docherty K.

    J Endocrinol. 2005 Aug;186(2):353-65.PMID: 16079261 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells.

    Buteau J, Roduit R, Susini S, Prentki M.

    Diabetologia. 1999 Jul;42(7):856-64.PMID: 10440129 [PubMed - indexed for MEDLINE]Related articles

    16.

    Glucose and glucoincretin peptides synergize to induce c-fos, c-jun, junB, zif-268, and nur-77 gene expression in pancreatic beta(INS-1) cells.

    Susini S, Roche E, Prentki M, Schlegel W.

    FASEB J. 1998 Sep;12(12):1173-82.PMID: 9737720 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter.

    Lawrence MC, McGlynn K, Park BH, Cobb MH.

    J Biol Chem. 2005 Jul 22;280(29):26751-9. Epub 2005 May 16.PMID: 15899886 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Ligand-induced regulation of glucagon-like peptide-I receptor function and expression in insulin-secreting beta cells.

    Fehmann HC, Jiang J, Pitt D, Schweinfurth J, Göke B.

    Pancreas. 1996 Oct;13(3):273-82.PMID: 8884849 [PubMed - indexed for MEDLINE]Related articles

    19.

    Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1.

    Delmeire D, Flamez D, Hinke SA, Cali JJ, Pipeleers D, Schuit F.

    Diabetologia. 2003 Oct;46(10):1383-93. Epub 2003 Sep 17.PMID: 13680124 [PubMed - indexed for MEDLINE]Related articles

    20.

    Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells.

    Briaud I, Lingohr MK, Dickson LM, Wrede CE, Rhodes CJ.

    Diabetes. 2003 Apr;52(4):974-83.PMID: 12663469 [PubMed - indexed for MEDLINE]Related articlesFree article

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