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    Results: 1 to 20 of 709

    1.

    Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats.

    Briaud I, Kelpe CL, Johnson LM, Tran PO, Poitout V.

    Diabetes. 2002 Mar;51(3):662-8.PMID: 11872664 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action.

    Chan CB, De Leo D, Joseph JW, McQuaid TS, Ha XF, Xu F, Tsushima RG, Pennefather PS, Salapatek AM, Wheeler MB.

    Diabetes. 2001 Jun;50(6):1302-10.PMID: 11375330 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Increasing triglyceride synthesis inhibits glucose-induced insulin secretion in isolated rat islets of langerhans: a study using adenoviral expression of diacylglycerol acyltransferase.

    Kelpe CL, Johnson LM, Poitout V.

    Endocrinology. 2002 Sep;143(9):3326-32.PMID: 12193544 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition.

    Patanè G, Anello M, Piro S, Vigneri R, Purrello F, Rabuazzo AM.

    Diabetes. 2002 Sep;51(9):2749-56.PMID: 12196468 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor attachment protein receptors in Goto-Kakizaki rats is partially restored by phlorizin treatment and accentuated by high glucose treatment.

    Gaisano HY, Ostenson CG, Sheu L, Wheeler MB, Efendic S.

    Endocrinology. 2002 Nov;143(11):4218-26.PMID: 12399415 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Effect of high dietary fat on insulin secretion in genetically diabetic Goto-Kakizaki rats.

    Shang W, Yasuda K, Takahashi A, Hamasaki A, Takehiro M, Nabe K, Zhou H, Naito R, Fujiwara H, Shimono D, Ueno H, Ikeda H, Toyoda K, Yamada Y, Kurose T.

    Pancreas. 2002 Nov;25(4):393-9.PMID: 12409835 [PubMed - indexed for MEDLINE]Related articles

    7.

    Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion.

    Nagamatsu S, Nakamichi Y, Yamamura C, Matsushima S, Watanabe T, Ozawa S, Furukawa H, Ishida H.

    Diabetes. 1999 Dec;48(12):2367-73.PMID: 10580425 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Influence of a high-fat diet during chronic hyperglycemia on beta-cell function in pancreatic islet transplants to streptozotocin-diabetic rats.

    Hiramatsu S, Grill V.

    Eur J Endocrinol. 2001 May;144(5):521-7.PMID: 11331219 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets.

    Hagman DK, Latour MG, Chakrabarti SK, Fontes G, Amyot J, Tremblay C, Semache M, Lausier JA, Roskens V, Mirmira RG, Jetton TL, Poitout V.

    Diabetes. 2008 Feb;57(2):424-31. Epub 2007 Nov 8.PMID: 17991758 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Role and mechanism of rosiglitazone on the impairment of insulin secretion induced by free fatty acids on isolated rat islets.

    Tian JY, Li G, Gu YY, Zhang HL, Zhou WZ, Wang X, Zhu HD, Luo TH, Luo M.

    Chin Med J (Engl). 2006 Apr 5;119(7):574-80.PMID: 16620699 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity.

    Poitout V, Robertson RP.

    Endocrinology. 2002 Feb;143(2):339-42. Review.PMID: 11796484 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Peroxisome proliferator-activated receptor gamma coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: a novel pathway for neural control of insulin secretion.

    De Souza CT, Gasparetti AL, Pereira-da-Silva M, Araújo EP, Carvalheira JB, Saad MJ, Boschero AC, Carneiro EM, Velloso LA.

    Diabetologia. 2003 Nov;46(11):1522-31. Epub 2003 Oct 24.PMID: 14576981 [PubMed - indexed for MEDLINE]Related articles

    13.

    Insulin secretion from islets of GK rats is not impaired after energy generating steps.

    Katayama N, Hughes SJ, Persaud SJ, Jones PM, Howell SL.

    Mol Cell Endocrinol. 1995 Jun;111(2):125-8.PMID: 7556873 [PubMed - indexed for MEDLINE]Related articles

    14.

    The role of islet secretory function in the development of diabetes in the GK Wistar rat.

    Hughes SJ, Suzuki K, Goto Y.

    Diabetologia. 1994 Sep;37(9):863-70.PMID: 7806015 [PubMed - indexed for MEDLINE]Related articles

    15.

    Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in rat islets cultured for 1 wk in high glucose.

    Khaldi MZ, Guiot Y, Gilon P, Henquin JC, Jonas JC.

    Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E207-17. Epub 2004 Apr 20.PMID: 15100093 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Overexpression of mitochondrial FAD-linked glycerol-3-phosphate dehydrogenase does not correct glucose-stimulated insulin secretion from diabetic GK rat pancreatic islets.

    Ueda K, Tanizawa Y, Ishihara H, Kizuki N, Ohta Y, Matsutani A, Oka Y.

    Diabetologia. 1998 Jun;41(6):649-53.PMID: 9662045 [PubMed - indexed for MEDLINE]Related articles

    17.

    Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function.

    Wang MY, Shimabukuro M, Lee Y, Trinh KY, Chen JL, Newgard CB, Unger RH.

    Diabetes. 1999 May;48(5):1020-5.PMID: 10331406 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice.

    Ahrén B, Simonsson E, Scheurink AJ, Mulder H, Myrsén U, Sundler F.

    Metabolism. 1997 Jan;46(1):97-106.PMID: 9005977 [PubMed - indexed for MEDLINE]Related articles

    19.

    Soybean- and olive-oils-enriched diets increase insulin secretion to glucose stimulus in isolated pancreatic rat islets.

    Picinato MC, Curi R, Machado UF, Carpinelli AR.

    Physiol Behav. 1998 Nov 15;65(2):289-94.PMID: 9855478 [PubMed - indexed for MEDLINE]Related articles

    20.

    Islet perturbations in rats fed a high-fat diet.

    Ahrén B, Gudbjartsson T, Al-Amin AN, Mårtensson H, Myrsén-Axcrona U, Karlsson S, Mulder H, Sundler F.

    Pancreas. 1999 Jan;18(1):75-83.PMID: 9888663 [PubMed - indexed for MEDLINE]Related articles

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