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    Results: 1 to 20 of 307

    1.

    Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice.

    Rabinovitch A, Suarez-Pinzon WL, Shapiro AM, Rajotte RV, Power R.

    Diabetes. 2002 Mar;51(3):638-45.PMID: 11872661 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice.

    Shapiro AM, Suarez-Pinzon WL, Power R, Rabinovitch A.

    Diabetologia. 2002 Feb;45(2):224-30.PMID: 11935154 [PubMed - indexed for MEDLINE]Related articles

    3.

    Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction.

    Suarez-Pinzon W, Rajotte RV, Mosmann TR, Rabinovitch A.

    Diabetes. 1996 Oct;45(10):1350-7.PMID: 8826970 [PubMed - indexed for MEDLINE]Related articles

    4.

    Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes.

    Suarez-Pinzon WL, Mabley JG, Power R, Szabó C, Rabinovitch A.

    Diabetes. 2003 Jul;52(7):1683-8.PMID: 12829633 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Combination therapy with cyclosporine and interleukin-4 or interleukin-10 prolongs survival of synergeneic pancreatic islet grafts in nonobese diabetic mice: islet graft survival does not correlate with mRNA levels of type 1 or type 2 cytokines, or transforming growth factor-beta in the islet grafts.

    Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Rajotte RV, Power RF.

    Transplantation. 1997 Dec 15;64(11):1525-31.PMID: 9415551 [PubMed - indexed for MEDLINE]Related articles

    6.

    IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death.

    Suk K, Kim S, Kim YH, Kim KA, Chang I, Yagita H, Shong M, Lee MS.

    J Immunol. 2001 Apr 1;166(7):4481-9.PMID: 11254704 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    A new type of CD4+ suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice.

    Han HS, Jun HS, Utsugi T, Yoon JW.

    J Autoimmun. 1996 Jun;9(3):331-9.PMID: 8816968 [PubMed - indexed for MEDLINE]Related articles

    8.

    Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice. Analysis of cytokine mRNA expression in the graft.

    Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Bleackley RC, Power RF, Rajotte RV.

    Transplantation. 1995 Aug 27;60(4):368-74.PMID: 7652767 [PubMed - indexed for MEDLINE]Related articles

    9.

    Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E.

    Hancock WW, Polanski M, Zhang J, Blogg N, Weiner HL.

    Am J Pathol. 1995 Nov;147(5):1193-9.PMID: 7485382 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Testicular sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism.

    Suarez-Pinzon W, Korbutt GS, Power R, Hooton J, Rajotte RV, Rabinovitch A.

    Diabetes. 2000 Nov;49(11):1810-8.PMID: 11078447 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Prevention of autoimmune diabetes in NOD mice by troglitazone is associated with modulation of ICAM-1 expression on pancreatic islet cells and IFN-gamma expression in splenic T cells.

    Augstein P, Dunger A, Heinke P, Wachlin G, Berg S, Hehmke B, Salzsieder E.

    Biochem Biophys Res Commun. 2003 May 2;304(2):378-84.PMID: 12711326 [PubMed - indexed for MEDLINE]Related articles

    12.

    Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets.

    Suarez-Pinzon W, Sorensen O, Bleackley RC, Elliott JF, Rajotte RV, Rabinovitch A.

    Diabetes. 1999 Jan;48(1):21-8.PMID: 9892218 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Gene transfection and expression of transforming growth factor-beta1 in nonobese diabetic mouse islets protects beta-cells in syngeneic islet grafts from autoimmune destruction.

    Suarez-Pinzon WL, Marcoux Y, Ghahary A, Rabinovitch A.

    Cell Transplant. 2002;11(6):519-28.PMID: 12428741 [PubMed - indexed for MEDLINE]Related articles

    14.

    NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen.

    Laloux V, Beaudoin L, Jeske D, Carnaud C, Lehuen A.

    J Immunol. 2001 Mar 15;166(6):3749-56.PMID: 11238616 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Roles of cytokines in the pathogenesis and therapy of type 1 diabetes.

    Rabinovitch A, Suarez-Pinzon WL.

    Cell Biochem Biophys. 2007;48(2-3):159-63.PMID: 17709885 [PubMed - indexed for MEDLINE]Related articles

    16.

    Primary nonfunction of islet grafts in autoimmune diabetic nonobese diabetic mice is prevented by treatment with interleukin-4 and interleukin-10.

    Faust A, Rothe H, Schade U, Lampeter E, Kolb H.

    Transplantation. 1996 Sep 15;62(5):648-52.PMID: 8830831 [PubMed - indexed for MEDLINE]Related articles

    17.

    TNF-alpha down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice.

    Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Rajotte RV, Power RF.

    J Immunol. 1997 Dec 15;159(12):6298-303.PMID: 9550435 [PubMed - indexed for MEDLINE]Related articles

    18.

    Nondepleting anti-CD4 and soluble interleukin-1 receptor prevent autoimmune destruction of syngeneic islet grafts in diabetic NOD mice.

    Drage M, Zaccone P, Phillips JM, Nicoletti F, Dawson J, Andrew Bradley J, Cooke A.

    Transplantation. 2002 Sep 15;74(5):611-9.PMID: 12352875 [PubMed - indexed for MEDLINE]Related articles

    19.

    IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma.

    Trembleau S, Penna G, Gregori S, Giarratana N, Adorini L.

    J Immunol. 2003 Jun 1;170(11):5491-501.PMID: 12759426 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Administration of IL-4 prevents autoimmune diabetes but enhances pancreatic insulitis in NOD mice.

    Tominaga Y, Nagata M, Yasuda H, Okamoto N, Arisawa K, Moriyama H, Miki M, Yokono K, Kasuga M.

    Clin Immunol Immunopathol. 1998 Feb;86(2):209-18.PMID: 9473384 [PubMed - indexed for MEDLINE]Related articles

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