PubMed

Effects of fasting on physiologically pulsatile insulin release in healthy humans.

Juhl C, Grøfte T, Butler PC, Veldhuis JD, Schmitz O, Pørksen N.

Diabetes. 2002 Feb;51 Suppl 1:S255-7.PMID: 11815488 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion.

Pørksen N, Grøfte B, Nyholm B, Holst JJ, Pincus SM, Veldhuis JD, Schmitz O, Butler PC.

Diabetes. 1998 Jan;47(1):45-9.PMID: 9421373 [PubMed - indexed for MEDLINE]Related articles

Human insulin release processes measured by intraportal sampling.

Pørksen N, Grøfte T, Greisen J, Mengel A, Juhl C, Veldhuis JD, Schmitz O, Rössle M, Vilstrup H.

Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E695-702.PMID: 11832375 [PubMed - indexed for MEDLINE]Related articlesFree article

In humans at least 75% of insulin secretion arises from punctuated insulin secretory bursts.

Pørksen N, Nyholm B, Veldhuis JD, Butler PC, Schmitz O.

Am J Physiol. 1997 Nov;273(5 Pt 1):E908-14.PMID: 9374676 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans.

Meier JJ, Veldhuis JD, Butler PC.

Diabetes. 2005 Jun;54(6):1649-56.PMID: 15919785 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose stimulates pulsatile insulin secretion from human pancreatic islets by increasing secretory burst mass: dose-response relationships.

Ritzel RA, Veldhuis JD, Butler PC.

J Clin Endocrinol Metab. 2003 Feb;88(2):742-7.PMID: 12574208 [PubMed - indexed for MEDLINE]Related articlesFree article

Concordant induction of rapid in vivo pulsatile insulin secretion by recurrent punctuated glucose infusions.

Pørksen N, Juhl C, Hollingdal M, Pincus SM, Sturis J, Veldhuis JD, Schmitz O.

Am J Physiol Endocrinol Metab. 2000 Jan;278(1):E162-70.PMID: 10644551 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of glucose ingestion versus infusion on pulsatile insulin secretion. The incretin effect is achieved by amplification of insulin secretory burst mass.

Pørksen N, Munn S, Steers J, Veldhuis JD, Butler PC.

Diabetes. 1996 Oct;45(10):1317-23.PMID: 8826965 [PubMed - indexed for MEDLINE]Related articles

Homeostatic joint amplification of pulsatile and 24-hour rhythmic cortisol secretion by fasting stress in midluteal phase women: concurrent disruption of cortisol-growth hormone, cortisol-luteinizing hormone, and cortisol-leptin synchrony.

Bergendahl M, Iranmanesh A, Pastor C, Evans WS, Veldhuis JD.

J Clin Endocrinol Metab. 2000 Nov;85(11):4028-35.PMID: 11095428 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of sulfonylurea's stimulation of insulin secretion in vivo: selective amplification of insulin secretory burst mass.

Pørksen NK, Munn SR, Steers JL, Schmitz O, Veldhuis JD, Butler PC.

Diabetes. 1996 Dec;45(12):1792-7.PMID: 8922367 [PubMed - indexed for MEDLINE]Related articles

Repaglinide acutely amplifies pulsatile insulin secretion by augmentation of burst mass with no effect on burst frequency.

Juhl CB, Pørksen N, Hollingdal M, Sturis J, Pincus S, Veldhuis JD, Dejgaard A, Schmitz O.

Diabetes Care. 2000 May;23(5):675-81.PMID: 10834429 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of somatostatin on pulsatile insulin secretion: elective inhibition of insulin burst mass.

Pørksen N, Munn SR, Steers JL, Veldhuis JD, Butler PC.

Am J Physiol. 1996 Jun;270(6 Pt 1):E1043-9.PMID: 8764190 [PubMed - indexed for MEDLINE]Related articles

Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes.

Hollingdal M, Juhl CB, Pincus SM, Sturis J, Veldhuis JD, Polonsky KS, Pørksen N, Schmitz O.

Diabetes. 2000 Aug;49(8):1334-40.PMID: 10923634 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-I inhibits burst mass of pulsatile insulin secretion at supraphysiological and low IGF-I infusion rates.

Pørksen N, Hussain MA, Bianda TL, Nyholm B, Christiansen JS, Butler PC, Veldhuis JD, Froesch ER, Schmitz O.

Am J Physiol. 1997 Mar;272(3 Pt 1):E352-8.PMID: 9124538 [PubMed - indexed for MEDLINE]Related articles

Pulsatile insulin secretion accounts for 70% of total insulin secretion during fasting.

Pørksen N, Munn S, Steers J, Vore S, Veldhuis J, Butler P.

Am J Physiol. 1995 Sep;269(3 Pt 1):E478-88.PMID: 7573425 [PubMed - indexed for MEDLINE]Related articles

The mass, but not the frequency, of insulin secretory bursts in isolated human islets is entrained by oscillatory glucose exposure.

Ritzel RA, Veldhuis JD, Butler PC.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E750-6. Epub 2005 Nov 8.PMID: 16278244 [PubMed - indexed for MEDLINE]Related articlesFree article

Repaglinide treatment amplifies first-phase insulin secretion and high-frequency pulsatile insulin release in Type 2 diabetes.

Hollingdal M, Sturis J, Gall MA, Damsbo P, Pincus S, Veldhuis JD, Pørksen N, Schmitz O, Juhl CB.

Diabet Med. 2005 Oct;22(10):1408-13.PMID: 16176204 [PubMed - indexed for MEDLINE]Related articles

Pulsatile insulin secretion: detection, regulation, and role in diabetes.

Pørksen N, Hollingdal M, Juhl C, Butler P, Veldhuis JD, Schmitz O.

Diabetes. 2002 Feb;51 Suppl 1:S245-54. Review.PMID: 11815487 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulsatile insulin secretion by human pancreatic islets.

Song SH, Kjems L, Ritzel R, McIntyre SM, Johnson ML, Veldhuis JD, Butler PC.

J Clin Endocrinol Metab. 2002 Jan;87(1):213-21.PMID: 11788649 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulsatile insulin release from islets isolated from three subjects with type 2 diabetes.

Lin JM, Fabregat ME, Gomis R, Bergsten P.

Diabetes. 2002 Apr;51(4):988-93.PMID: 11916916 [PubMed - indexed for MEDLINE]Related articlesFree article