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Pulsatile insulin secretion: detection, regulation, and role in diabetes.
Pørksen N, Hollingdal M, Juhl C, Butler P, Veldhuis JD, Schmitz O.
Diabetes. 2002 Feb;51 Suppl 1:S245-54. Review.PMID: 11815487 [PubMed - indexed for MEDLINE]Related articlesFree article
The in vivo regulation of pulsatile insulin secretion.
Pørksen N.
Diabetologia. 2002 Jan;45(1):3-20. Review.PMID: 11845219 [PubMed - indexed for MEDLINE]Related articles
Early changes in beta-cell function and insulin pulsatility as predictors for type 2 diabetes.
Diabetes Nutr Metab. 2002 Dec;15(6 Suppl):9-14. Review.PMID: 12702002 [PubMed - indexed for MEDLINE]Related articles
Human insulin release processes measured by intraportal sampling.
Pørksen N, Grøfte T, Greisen J, Mengel A, Juhl C, Veldhuis JD, Schmitz O, Rössle M, Vilstrup H.
Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E695-702.PMID: 11832375 [PubMed - indexed for MEDLINE]Related articlesFree article
High-frequency insulin pulsatility and type 2 diabetes: from physiology and pathophysiology to clinical pharmacology.
Schmitz O, Brock B, Hollingdal M, Juhl CB, Pørksen N.
Diabetes Metab. 2002 Dec;28(6 Suppl):4S14-20. Review.PMID: 12703061 [PubMed - indexed for MEDLINE]Related articlesFree article
Loss of beta-cell mass leads to a reduction of pulse mass with normal periodicity, regularity and entrainment of pulsatile insulin secretion in Göttingen minipigs.
Larsen MO, Gotfredsen CF, Wilken M, Carr RD, Pørksen N, Rolin B.
Diabetologia. 2003 Feb;46(2):195-202. Epub 2003 Jan 11. Erratum in: Diabetologia. 2004 Jan;47(1):155. PMID: 12627318 [PubMed - indexed for MEDLINE]Related articles
Effects of fasting on physiologically pulsatile insulin release in healthy humans.
Juhl C, Grøfte T, Butler PC, Veldhuis JD, Schmitz O, Pørksen N.
Diabetes. 2002 Feb;51 Suppl 1:S255-7.PMID: 11815488 [PubMed - indexed for MEDLINE]Related articlesFree article
The mass, but not the frequency, of insulin secretory bursts in isolated human islets is entrained by oscillatory glucose exposure.
Ritzel RA, Veldhuis JD, Butler PC.
Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E750-6. Epub 2005 Nov 8.PMID: 16278244 [PubMed - indexed for MEDLINE]Related articlesFree article
Pathophysiology of impaired pulsatile insulin release.
Bergsten P.
Diabetes Metab Res Rev. 2000 May-Jun;16(3):179-91. Review.PMID: 10867718 [PubMed - indexed for MEDLINE]Related articles
On high-frequency insulin oscillations.
Schmitz O, Rungby J, Edge L, Juhl CB.
Ageing Res Rev. 2008 Dec;7(4):301-5. Epub 2008 May 3. Review.PMID: 18583199 [PubMed - indexed for MEDLINE]Related articles
In humans at least 75% of insulin secretion arises from punctuated insulin secretory bursts.
Pørksen N, Nyholm B, Veldhuis JD, Butler PC, Schmitz O.
Am J Physiol. 1997 Nov;273(5 Pt 1):E908-14.PMID: 9374676 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucose stimulates pulsatile insulin secretion from human pancreatic islets by increasing secretory burst mass: dose-response relationships.
J Clin Endocrinol Metab. 2003 Feb;88(2):742-7.PMID: 12574208 [PubMed - indexed for MEDLINE]Related articlesFree article
Greater in vivo than in vitro pulsatility of insulin secretion with synchronized insulin and somatostatin secretory pulses.
Matthews DR, Hermansen K, Connolly AA, Gray D, Schmitz O, Clark A, Orskov H, Turner RC.
Endocrinology. 1987 Jun;120(6):2272-8.PMID: 2883001 [PubMed - indexed for MEDLINE]Related articles
Control mechanisms of the oscillations of insulin secretion in vitro and in vivo.
Gilon P, Ravier MA, Jonas JC, Henquin JC.
Diabetes. 2002 Feb;51 Suppl 1:S144-51. Review.PMID: 11815474 [PubMed - indexed for MEDLINE]Related articlesFree article
Pulsatile insulin release from islets isolated from three subjects with type 2 diabetes.
Lin JM, Fabregat ME, Gomis R, Bergsten P.
Diabetes. 2002 Apr;51(4):988-93.PMID: 11916916 [PubMed - indexed for MEDLINE]Related articlesFree article
Phasic insulin release and metabolic regulation in type 2 diabetes.
Del Prato S, Marchetti P, Bonadonna RC.
Diabetes. 2002 Feb;51 Suppl 1:S109-16. Review.PMID: 11815468 [PubMed - indexed for MEDLINE]Related articlesFree article
Concordant induction of rapid in vivo pulsatile insulin secretion by recurrent punctuated glucose infusions.
Pørksen N, Juhl C, Hollingdal M, Pincus SM, Sturis J, Veldhuis JD, Schmitz O.
Am J Physiol Endocrinol Metab. 2000 Jan;278(1):E162-70.PMID: 10644551 [PubMed - indexed for MEDLINE]Related articlesFree article
Repaglinide treatment amplifies first-phase insulin secretion and high-frequency pulsatile insulin release in Type 2 diabetes.
Hollingdal M, Sturis J, Gall MA, Damsbo P, Pincus S, Veldhuis JD, Pørksen N, Schmitz O, Juhl CB.
Diabet Med. 2005 Oct;22(10):1408-13.PMID: 16176204 [PubMed - indexed for MEDLINE]Related articles
Oscillatory control of insulin secretion.
Tengholm A, Gylfe E.
Mol Cell Endocrinol. 2009 Jan 15;297(1-2):58-72. Epub 2008 Jul 26. Review.PMID: 18706473 [PubMed - indexed for MEDLINE]Related articles
Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets.
Song SH, Rhodes CJ, Veldhuis JD, Butler PC.
Endocrinology. 2003 Aug;144(8):3399-405.PMID: 12865318 [PubMed - indexed for MEDLINE]Related articlesFree article
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