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    Results: 1 to 20 of 358

    1.

    Altered beta-cell distribution of pdx-1 and GLUT-2 after a short-term challenge with a high-fat diet in C57BL/6J mice.

    Reimer MK, Ahrén B.

    Diabetes. 2002 Feb;51 Suppl 1:S138-43.PMID: 11815473 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice.

    Ahrén B, Simonsson E, Scheurink AJ, Mulder H, Myrsén U, Sundler F.

    Metabolism. 1997 Jan;46(1):97-106.PMID: 9005977 [PubMed - indexed for MEDLINE]Related articles

    3.

    Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice.

    Reimer MK, Holst JJ, Ahrén B.

    Eur J Endocrinol. 2002 May;146(5):717-27.PMID: 11980629 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice.

    Winzell MS, Magnusson C, Ahrén B.

    Metabolism. 2007 Jan;56(1):122-8.PMID: 17161234 [PubMed - indexed for MEDLINE]Related articles

    5.

    Islet perturbations in rats fed a high-fat diet.

    Ahrén B, Gudbjartsson T, Al-Amin AN, Mårtensson H, Myrsén-Axcrona U, Karlsson S, Mulder H, Sundler F.

    Pancreas. 1999 Jan;18(1):75-83.PMID: 9888663 [PubMed - indexed for MEDLINE]Related articles

    6.

    Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.

    Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M.

    Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23.PMID: 11904435 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo.

    Tremblay F, Richard AM, Will S, Syed J, Stedman N, Perreault M, Gimeno RE.

    Endocrinology. 2009 Jun;150(6):2586-95. Epub 2009 Feb 12.PMID: 19213841 [PubMed - indexed for MEDLINE]Related articles

    8.

    Early and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B.

    Walz HA, Härndahl L, Wierup N, Zmuda-Trzebiatowska E, Svennelid F, Manganiello VC, Ploug T, Sundler F, Degerman E, Ahrén B, Holst LS.

    J Endocrinol. 2006 Jun;189(3):629-41.PMID: 16731793 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Durable islet effects on insulin secretion and protein kinase A expression following exendin-4 treatment of high-fat diet-fed mice.

    Winzell MS, Ahrén B.

    J Mol Endocrinol. 2008 Feb;40(2):93-100.PMID: 18234911 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis.

    Brissova M, Blaha M, Spear C, Nicholson W, Radhika A, Shiota M, Charron MJ, Wright CV, Powers AC.

    Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E707-14. Epub 2004 Nov 23.PMID: 15562255 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The Tet-On system in transgenic mice: inhibition of the mouse pdx-1 gene activity by antisense RNA expression in pancreatic beta-cells.

    Lottmann H, Vanselow J, Hessabi B, Walther R.

    J Mol Med. 2001 Jun;79(5-6):321-8.PMID: 11485027 [PubMed - indexed for MEDLINE]Related articles

    12.

    Interaction between BTBR and C57BL/6J genomes produces an insulin resistance syndrome in (BTBR x C57BL/6J) F1 mice.

    Ranheim T, Dumke C, Schueler KL, Cartee GD, Attie AD.

    Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):3286-93.PMID: 9409324 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet.

    Winzell MS, Brand CL, Wierup N, Sidelmann UG, Sundler F, Nishimura E, Ahrén B.

    Diabetologia. 2007 Jul;50(7):1453-62. Epub 2007 May 4.PMID: 17479245 [PubMed - indexed for MEDLINE]Related articles

    14.

    A high fat diet impairs stimulation of glucose transport in muscle. Functional evaluation of potential mechanisms.

    Hansen PA, Han DH, Marshall BA, Nolte LA, Chen MM, Mueckler M, Holloszy JO.

    J Biol Chem. 1998 Oct 2;273(40):26157-63.PMID: 9748297 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.

    Fex M, Nitert MD, Wierup N, Sundler F, Ling C, Mulder H.

    Diabetologia. 2007 Jan;50(1):74-83. Epub 2006 Nov 9.PMID: 17093947 [PubMed - indexed for MEDLINE]Related articles

    17.

    Pdx1 expression in Irs2-deficient mouse beta-cells is regulated in a strain-dependent manner.

    Suzuki R, Tobe K, Terauchi Y, Komeda K, Kubota N, Eto K, Yamauchi T, Azuma K, Kaneto H, Taguchi T, Koga T, German MS, Watada H, Kawamori R, Wright CV, Kajimoto Y, Kimura S, Nagai R, Kadowaki T.

    J Biol Chem. 2003 Oct 31;278(44):43691-8. Epub 2003 Jul 16.PMID: 12869553 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Increased insulin secretion and normalization of glucose tolerance by cholinergic agonism in high fat-fed mice.

    Ahrén B, Sauerberg P, Thomsen C.

    Am J Physiol. 1999 Jul;277(1 Pt 1):E93-102.PMID: 10409132 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Expression of PDX-1 is reduced in pancreatic islets from pups of rat dams fed a low protein diet during gestation and lactation.

    Arantes VC, Teixeira VP, Reis MA, Latorraca MQ, Leite AR, Carneiro EM, Yamada AT, Boschero AC.

    J Nutr. 2002 Oct;132(10):3030-5.PMID: 12368391 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Comparison of insulin secretory function in two mouse models with different susceptibility to beta-cell failure.

    Kooptiwut S, Zraika S, Thorburn AW, Dunlop ME, Darwiche R, Kay TW, Proietto J, Andrikopoulos S.

    Endocrinology. 2002 Jun;143(6):2085-92.PMID: 12021173 [PubMed - indexed for MEDLINE]Related articlesFree article

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