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    Results: 1 to 20 of 110

    1.

    Clinical characterization of insulin secretion as the basis for genetic analyses.

    Stumvoll M, Fritsche A, Häring HU.

    Diabetes. 2002 Feb;51 Suppl 1:S122-9. Review.PMID: 11815470 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism.

    Marchetti P, Lupi R, Federici M, Marselli L, Masini M, Boggi U, Del Guerra S, Patanè G, Piro S, Anello M, Bergamini E, Purrello F, Lauro R, Mosca F, Sesti G, Del Prato S.

    Diabetes. 2002 May;51(5):1419-24.PMID: 11978638 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    The prevalent Gly1057Asp polymorphism in the insulin receptor substrate-2 gene is not associated with impaired insulin secretion.

    Fritsche A, Madaus A, Renn W, Tschritter O, Teigeler A, Weisser M, Maerker E, Machicao F, Häring H, Stumvoll M.

    J Clin Endocrinol Metab. 2001 Oct;86(10):4822-5.PMID: 11600548 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans.

    Stumvoll M, Fritsche A, Volk A, Stefan N, Madaus A, Maerker E, Teigeler A, Koch M, Machicao F, Häring H.

    Diabetes. 2001 Apr;50(4):882-5.PMID: 11289056 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion.

    Schäfer SA, Müssig K, Staiger H, Machicao F, Stefan N, Gallwitz B, Häring HU, Fritsche A.

    Diabetologia. 2009 Jun;52(6):1075-82. Epub 2009 Mar 28.PMID: 19330314 [PubMed - indexed for MEDLINE]Related articles

    6.

    Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose.

    Greenbaum CJ, Prigeon RL, D'Alessio DA.

    Diabetes. 2002 Apr;51(4):951-7.PMID: 11916912 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Apoptosis in the beta cells: cause or consequence of insulin secretion defect in diabetes?

    Sesti G.

    Ann Med. 2002;34(6):444-50. Review.PMID: 12523500 [PubMed - indexed for MEDLINE]Related articles

    8.

    The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects.

    Kjems LL, Holst JJ, Vølund A, Madsbad S.

    Diabetes. 2003 Feb;52(2):380-6.PMID: 12540611 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes.

    Degn KB, Juhl CB, Sturis J, Jakobsen G, Brock B, Chandramouli V, Rungby J, Landau BR, Schmitz O.

    Diabetes. 2004 May;53(5):1187-94.PMID: 15111485 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus.

    Vilsbøll T, Krarup T, Sonne J, Madsbad S, Vølund A, Juul AG, Holst JJ.

    J Clin Endocrinol Metab. 2003 Jun;88(6):2706-13.PMID: 12788877 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes.

    Meier JJ, Gallwitz B, Askenas M, Vollmer K, Deacon CF, Holst JJ, Schmidt WE, Nauck MA.

    Diabetologia. 2005 Sep;48(9):1872-81. Epub 2005 Jul 12.PMID: 16010522 [PubMed - indexed for MEDLINE]Related articles

    12.

    A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes.

    Kashyap S, Belfort R, Gastaldelli A, Pratipanawatr T, Berria R, Pratipanawatr W, Bajaj M, Mandarino L, DeFronzo R, Cusi K.

    Diabetes. 2003 Oct;52(10):2461-74.PMID: 14514628 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans.

    Quddusi S, Vahl TP, Hanson K, Prigeon RL, D'Alessio DA.

    Diabetes Care. 2003 Mar;26(3):791-8.PMID: 12610039 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes.

    Mari A, Sallas WM, He YL, Watson C, Ligueros-Saylan M, Dunning BE, Deacon CF, Holst JJ, Foley JE.

    J Clin Endocrinol Metab. 2005 Aug;90(8):4888-94. Epub 2005 May 10.PMID: 15886245 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Characterization of beta-cell function impairment in first-degree relatives of type 2 diabetic subjects: modeling analysis of 24-h triple-meal tests.

    Mari A, Gastaldelli A, Natali A, Ostergard T, Schmitz O, Ferrannini E.

    Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E541-6. Epub 2004 Nov 2.PMID: 15522997 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Pathogenic mechanism of type 2 diabetes in Ghanaians--the importance of beta cell secretion, insulin sensitivity and glucose effectiveness.

    Amoah AG, Owusu SK, Schuster DP, Osei K.

    S Afr Med J. 2002 May;92(5):377-84.PMID: 12108171 [PubMed - indexed for MEDLINE]Related articles

    17.

    Altered homeostatic adaptation of first- and second-phase beta-cell secretion in the offspring of patients with type 2 diabetes: studies with a minimal model to assess beta-cell function.

    Bonadonna RC, Stumvoll M, Fritsche A, Muggeo M, Häring H, Bonora E, van Haeften TW.

    Diabetes. 2003 Feb;52(2):470-80.PMID: 12540623 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia.

    Tschritter O, Stumvoll M, Machicao F, Holzwarth M, Weisser M, Maerker E, Teigeler A, Häring H, Fritsche A.

    Diabetes. 2002 Sep;51(9):2854-60.PMID: 12196481 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Early disturbances in insulin secretion in the development of type 2 diabetes mellitus.

    van Haeften TW.

    Mol Cell Endocrinol. 2002 Nov 29;197(1-2):197-204. Review.PMID: 12431813 [PubMed - indexed for MEDLINE]Related articles

    20.

    Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.

    Nauck MA, El-Ouaghlidi A, Gabrys B, Hücking K, Holst JJ, Deacon CF, Gallwitz B, Schmidt WE, Meier JJ.

    Regul Pept. 2004 Nov 15;122(3):209-17.PMID: 15491793 [PubMed - indexed for MEDLINE]Related articles

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