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    Results: 1 to 20 of 129

    1.

    Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion.

    Bratanova-Tochkova TK, Cheng H, Daniel S, Gunawardana S, Liu YJ, Mulvaney-Musa J, Schermerhorn T, Straub SG, Yajima H, Sharp GW.

    Diabetes. 2002 Feb;51 Suppl 1:S83-90. Review.PMID: 11815463 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Glucose-stimulated signaling pathways in biphasic insulin secretion.

    Straub SG, Sharp GW.

    Diabetes Metab Res Rev. 2002 Nov-Dec;18(6):451-63. Review.PMID: 12469359 [PubMed - indexed for MEDLINE]Related articles

    3.

    Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose-stimulated insulin secretion.

    Straub SG, Sharp GW.

    Am J Physiol Cell Physiol. 2004 Sep;287(3):C565-71. Review.PMID: 15308461 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells.

    Barg S, Eliasson L, Renström E, Rorsman P.

    Diabetes. 2002 Feb;51 Suppl 1:S74-82. Review.PMID: 11815462 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway.

    Thams P, Anwar MR, Capito K.

    Eur J Endocrinol. 2005 Apr;152(4):671-7.PMID: 15817925 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells.

    Olofsson CS, Salehi A, Holm C, Rorsman P.

    J Physiol. 2004 Jun 15;557(Pt 3):935-48. Epub 2004 Apr 16.PMID: 15090611 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Insulin granule biogenesis, trafficking and exocytosis.

    Hou JC, Min L, Pessin JE.

    Vitam Horm. 2009;80:473-506. Review.PMID: 19251047 [PubMed - indexed for MEDLINE]Related articles

    8.

    Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.

    Fransson U, Rosengren AH, Schuit FC, Renström E, Mulder H.

    Diabetologia. 2006 Jul;49(7):1578-86. Epub 2006 Apr 26.PMID: 16752176 [PubMed - indexed for MEDLINE]Related articles

    9.

    Hyposmotic shock stimulates insulin secretion by two distinct mechanisms. Studies with the betaHC9 cell.

    Straub SG, Daniel S, Sharp GW.

    Am J Physiol Endocrinol Metab. 2002 May;282(5):E1070-6.PMID: 11934672 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion.

    Daniel S, Noda M, Straub SG, Sharp GW.

    Diabetes. 1999 Sep;48(9):1686-90.PMID: 10480595 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic beta cells.

    Olsen HL, Hoy M, Zhang W, Bertorello AM, Bokvist K, Capito K, Efanov AM, Meister B, Thams P, Yang SN, Rorsman P, Berggren PO, Gromada J.

    Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5187-92. Epub 2003 Apr 16.PMID: 12700357 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.

    Høy M, Olsen HL, Andersen HS, Bokvist K, Buschard K, Hansen J, Jacobsen P, Petersen JS, Rorsman P, Gromada J.

    Eur J Pharmacol. 2003 Apr 11;466(1-2):213-21.PMID: 12679159 [PubMed - indexed for MEDLINE]Related articles

    13.

    Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells.

    Nenquin M, Szollosi A, Aguilar-Bryan L, Bryan J, Henquin JC.

    J Biol Chem. 2004 Jul 30;279(31):32316-24. Epub 2004 Jun 1.PMID: 15175349 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Rapid ATP-dependent priming of secretory granules precedes Ca(2+)-induced exocytosis in mouse pancreatic B-cells.

    Eliasson L, Renström E, Ding WG, Proks P, Rorsman P.

    J Physiol. 1997 Sep 1;503 ( Pt 2):399-412.PMID: 9306281 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Signals and pools underlying biphasic insulin secretion.

    Henquin JC, Ishiyama N, Nenquin M, Ravier MA, Jonas JC.

    Diabetes. 2002 Feb;51 Suppl 1:S60-7. Review.PMID: 11815460 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels.

    Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

    J Biol Chem. 2007 Jan 19;282(3):1747-56. Epub 2006 Nov 30.PMID: 17138557 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis.

    Donelan MJ, Morfini G, Julyan R, Sommers S, Hays L, Kajio H, Briaud I, Easom RA, Molkentin JD, Brady ST, Rhodes CJ.

    J Biol Chem. 2002 Jul 5;277(27):24232-42. Epub 2002 Apr 26.PMID: 11978799 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Newcomer insulin secretory granules as a highly calcium-sensitive pool.

    Pedersen MG, Sherman A.

    Proc Natl Acad Sci U S A. 2009 May 5;106(18):7432-6. Epub 2009 Apr 16.PMID: 19372374 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal.

    Szollosi A, Nenquin M, Henquin JC.

    J Biol Chem. 2007 May 18;282(20):14768-76. Epub 2007 Mar 27.PMID: 17389589 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Importance of nonionic signals for glucose-induced biphasic insulin secretion.

    Aizawa T, Sato Y, Komatsu M.

    Diabetes. 2002 Feb;51 Suppl 1:S96-8. Review.PMID: 11815465 [PubMed - indexed for MEDLINE]Related articlesFree article

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