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    Results: 1 to 20 of 149

    1.

    Beta-cell mitochondria and insulin secretion: messenger role of nucleotides and metabolites.

    Wollheim CB, Maechler P.

    Diabetes. 2002 Feb;51 Suppl 1:S37-42. Review.PMID: 11815456 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells.

    Maechler P.

    Cell Mol Life Sci. 2002 Nov;59(11):1803-18. Review.PMID: 12530515 [PubMed - indexed for MEDLINE]Related articles

    3.

    Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

    Maechler P, Wollheim CB.

    Nature. 1999 Dec 9;402(6762):685-9.PMID: 10604477 [PubMed - indexed for MEDLINE]Related articles

    4.

    Amino acid metabolism, insulin secretion and diabetes.

    Newsholme P, Bender K, Kiely A, Brennan L.

    Biochem Soc Trans. 2007 Nov;35(Pt 5):1180-6. Review.PMID: 17956307 [PubMed - indexed for MEDLINE]Related articles

    5.

    New insights into amino acid metabolism, beta-cell function and diabetes.

    Newsholme P, Brennan L, Rubi B, Maechler P.

    Clin Sci (Lond). 2005 Mar;108(3):185-94. Review.PMID: 15544573 [PubMed - indexed for MEDLINE]Related articles

    6.

    Glucose-stimulated signaling pathways in biphasic insulin secretion.

    Straub SG, Sharp GW.

    Diabetes Metab Res Rev. 2002 Nov-Dec;18(6):451-63. Review.PMID: 12469359 [PubMed - indexed for MEDLINE]Related articles

    7.

    Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

    Maechler P, Kennedy ED, Pozzan T, Wollheim CB.

    EMBO J. 1997 Jul 1;16(13):3833-41.PMID: 9233793 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell.

    Maechler P, Wollheim CB.

    J Physiol. 2000 Nov 15;529 Pt 1:49-56. Review.PMID: 11080250 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells.

    Nenquin M, Szollosi A, Aguilar-Bryan L, Bryan J, Henquin JC.

    J Biol Chem. 2004 Jul 30;279(31):32316-24. Epub 2004 Jun 1.PMID: 15175349 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels.

    Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

    J Biol Chem. 2007 Jan 19;282(3):1747-56. Epub 2006 Nov 30.PMID: 17138557 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Metabolic coupling factors in pancreatic beta-cell signal transduction.

    Newgard CB, McGarry JD.

    Annu Rev Biochem. 1995;64:689-719. Review.PMID: 7574498 [PubMed - indexed for MEDLINE]Related articles

    12.

    Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues.

    Antinozzi PA, Ishihara H, Newgard CB, Wollheim CB.

    J Biol Chem. 2002 Apr 5;277(14):11746-55. Epub 2002 Jan 30.PMID: 11821387 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.

    Høy M, Olsen HL, Andersen HS, Bokvist K, Buschard K, Hansen J, Jacobsen P, Petersen JS, Rorsman P, Gromada J.

    Eur J Pharmacol. 2003 Apr 11;466(1-2):213-21.PMID: 12679159 [PubMed - indexed for MEDLINE]Related articles

    14.

    Adenine and guanine nucleotide-specific succinyl-CoA synthetases in the clonal beta-cell mitochondria: implications in the beta-cell high-energy phosphate metabolism in relation to physiological insulin secretion.

    Kowluru A.

    Diabetologia. 2001 Jan;44(1):89-94.PMID: 11206416 [PubMed - indexed for MEDLINE]Related articles

    15.

    Fast and cAMP-sensitive mode of Ca(2+)-dependent exocytosis in pancreatic beta-cells.

    Kasai H, Suzuki T, Liu TT, Kishimoto T, Takahashi N.

    Diabetes. 2002 Feb;51 Suppl 1:S19-24.PMID: 11815452 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Methyl pyruvate initiates membrane depolarization and insulin release by metabolic factors other than ATP.

    Lembert N, Joos HC, Idahl LA, Ammon HP, Wahl MA.

    Biochem J. 2001 Mar 1;354(Pt 2):345-50.PMID: 11171113 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells.

    Wang H, Iezzi M, Theander S, Antinozzi PA, Gauthier BR, Halban PA, Wollheim CB.

    Diabetologia. 2005 Apr;48(4):720-31. Epub 2005 Mar 9.PMID: 15756539 [PubMed - indexed for MEDLINE]Related articles

    18.

    GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells.

    Rubi B, Ishihara H, Hegardt FG, Wollheim CB, Maechler P.

    J Biol Chem. 2001 Sep 28;276(39):36391-6. Epub 2001 Jul 25.PMID: 11473118 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis.

    Shibasaki T, Sunaga Y, Fujimoto K, Kashima Y, Seino S.

    J Biol Chem. 2004 Feb 27;279(9):7956-61. Epub 2003 Dec 3.PMID: 14660679 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets.

    Lee B, Miles PD, Vargas L, Luan P, Glasco S, Kushnareva Y, Kornbrust ES, Grako KA, Wollheim CB, Maechler P, Olefsky JM, Anderson CM.

    Diabetes. 2003 Apr;52(4):965-73.PMID: 12663468 [PubMed - indexed for MEDLINE]Related articlesFree article

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