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Role of electrostatic and hydrophobic interactions in Ca(2+)-dependent phospholipid binding by the C(2)A-domain from synaptotagmin I.
Gerber SH, Rizo J, Südhof TC.
Diabetes. 2002 Feb;51 Suppl 1:S12-8.PMID: 11815451 [PubMed - indexed for MEDLINE]Related articlesFree article
Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I.
Zhang X, Rizo J, Südhof TC.
Biochemistry. 1998 Sep 8;37(36):12395-403.PMID: 9730811 [PubMed - indexed for MEDLINE]Related articles
The C2A domain of synaptotagmin-like protein 3 (Slp3) is an atypical calcium-dependent phospholipid-binding machine: comparison with the C2A domain of synaptotagmin I.
Fukuda M.
Biochem J. 2002 Sep 1;366(Pt 2):681-7.PMID: 12049610 [PubMed - indexed for MEDLINE]Related articlesFree article
Structure/function analysis of Ca2+ binding to the C2A domain of synaptotagmin 1.
Fernández-Chacón R, Shin OH, Königstorfer A, Matos MF, Meyer AC, Garcia J, Gerber SH, Rizo J, Südhof TC, Rosenmund C.
J Neurosci. 2002 Oct 1;22(19):8438-46.PMID: 12351718 [PubMed - indexed for MEDLINE]Related articlesFree article
Synaptotagmins I and IV promote transmitter release independently of Ca(2+) binding in the C(2)A domain.
Robinson IM, Ranjan R, Schwarz TL.
Nature. 2002 Jul 18;418(6895):336-40. Epub 2002 Jul 7.PMID: 12110845 [PubMed - indexed for MEDLINE]Related articles
A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.
Davletov BA, Südhof TC.
J Biol Chem. 1993 Dec 15;268(35):26386-90.PMID: 8253763 [PubMed - indexed for MEDLINE]Related articlesFree article
Synaptotagmin function in dense core vesicle exocytosis studied in cracked PC12 cells.
Shin OH, Rizo J, Südhof TC.
Nat Neurosci. 2002 Jul;5(7):649-56.PMID: 12055633 [PubMed - indexed for MEDLINE]Related articles
Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4.
Dai H, Shin OH, Machius M, Tomchick DR, Südhof TC, Rizo J.
Nat Struct Mol Biol. 2004 Sep;11(9):844-9. Epub 2004 Aug 15.PMID: 15311271 [PubMed - indexed for MEDLINE]Related articles
The top loops of the C(2) domains from synaptotagmin and phospholipase A(2) control functional specificity.
J Biol Chem. 2001 Aug 24;276(34):32288-92. Epub 2001 Jul 10.PMID: 11447211 [PubMed - indexed for MEDLINE]Related articlesFree article
Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV.
Fukuda M, Kojima T, Mikoshiba K.
J Biol Chem. 1996 Apr 5;271(14):8430-4.PMID: 8626542 [PubMed - indexed for MEDLINE]Related articlesFree article
The C2B domain of synaptotagmin I is a Ca2+-binding module.
Ubach J, Lao Y, Fernandez I, Arac D, Südhof TC, Rizo J.
Biochemistry. 2001 May 22;40(20):5854-60.PMID: 11352720 [PubMed - indexed for MEDLINE]Related articles
The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo.
Mackler JM, Drummond JA, Loewen CA, Robinson IM, Reist NE.
Nature. 2002 Jul 18;418(6895):340-4. Epub 2002 Jul 7.PMID: 12110842 [PubMed - indexed for MEDLINE]Related articles
Functional analysis of the C2A domain of synaptotagmin 1: implications for calcium-regulated secretion.
Thomas DM, Elferink LA.
J Neurosci. 1998 May 15;18(10):3511-20.PMID: 9570782 [PubMed - indexed for MEDLINE]Related articlesFree article
Membrane-embedded synaptotagmin penetrates cis or trans target membranes and clusters via a novel mechanism.
Bai J, Earles CA, Lewis JL, Chapman ER.
J Biol Chem. 2000 Aug 18;275(33):25427-35.PMID: 10840045 [PubMed - indexed for MEDLINE]Related articlesFree article
Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold.
Sutton RB, Davletov BA, Berghuis AM, Südhof TC, Sprang SR.
Cell. 1995 Mar 24;80(6):929-38.PMID: 7697723 [PubMed - indexed for MEDLINE]Related articles
Ca(2+)-dependent conformational change in synaptotagmin I.
J Biol Chem. 1994 Nov 18;269(46):28547-50.PMID: 7961798 [PubMed - indexed for MEDLINE]Related articlesFree article
Specificity of Ca2+-dependent protein interactions mediated by the C2A domains of synaptotagmins.
Sugita S, Südhof TC.
Biochemistry. 2000 Mar 21;39(11):2940-9.PMID: 10715114 [PubMed - indexed for MEDLINE]Related articles
Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction.
Sutton RB, Ernst JA, Brunger AT.
J Cell Biol. 1999 Nov 1;147(3):589-98.PMID: 10545502 [PubMed - indexed for MEDLINE]Related articlesFree article
Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin.
Coppola T, Magnin-Luthi S, Perret-Menoud V, Gattesco S, Schiavo G, Regazzi R.
J Biol Chem. 2001 Aug 31;276(35):32756-62. Epub 2001 Jul 3.PMID: 11438518 [PubMed - indexed for MEDLINE]Related articlesFree article
Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
Fernandez I, Araç D, Ubach J, Gerber SH, Shin O, Gao Y, Anderson RG, Südhof TC, Rizo J.
Neuron. 2001 Dec 20;32(6):1057-69.PMID: 11754837 [PubMed - indexed for MEDLINE]Related articles
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