PubMed

T-cell tolerance by dendritic cells and macrophages as a mechanism for the major histocompatibility complex-linked resistance to autoimmune diabetes.

Thiessen S, Serra P, Amrani A, Verdaguer J, Santamaria P.

Diabetes. 2002 Feb;51(2):325-38.PMID: 11812739 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoantigen-independent deletion of diabetogenic CD4+ thymocytes by protective MHC class II molecules.

Schmidt D, Amrani A, Verdaguer J, Bou S, Santamaria P.

J Immunol. 1999 Apr 15;162(8):4627-36.PMID: 10202002 [PubMed - indexed for MEDLINE]Related articlesFree article

A mechanism for the major histocompatibility complex-linked resistance to autoimmunity.

Schmidt D, Verdaguer J, Averill N, Santamaria P.

J Exp Med. 1997 Oct 6;186(7):1059-75.PMID: 9314555 [PubMed - indexed for MEDLINE]Related articlesFree article

Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities.

Lühder F, Katz J, Benoist C, Mathis D.

J Exp Med. 1998 Feb 2;187(3):379-87.PMID: 9449718 [PubMed - indexed for MEDLINE]Related articlesFree article

Thymic positive selection and peripheral activation of islet antigen-specific T cells: separation of two diabetogenic steps by an I-A(g7) class II MHC beta-chain mutant.

Kanagawa O, Vaupel BA, Xu G, Unanue ER, Katz JD.

J Immunol. 1998 Nov 1;161(9):4489-92.PMID: 9794372 [PubMed - indexed for MEDLINE]Related articlesFree article

MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.

Serreze DV, Holl TM, Marron MP, Graser RT, Johnson EA, Choisy-Rossi C, Slattery RM, Lieberman SM, DiLorenzo TP.

J Immunol. 2004 Jan 15;172(2):871-9.PMID: 14707058 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-12 administration reveals diabetogenic T cells in genetically resistant I-Ealpha-transgenic nonobese diabetic mice: resistance to autoimmune diabetes is associated with binding of Ealpha-derived peptides to the I-A(g7) molecule.

Trembleau S, Gregori S, Penna G, Gorny I, Adorini L.

J Immunol. 2001 Oct 1;167(7):4104-14.PMID: 11564833 [PubMed - indexed for MEDLINE]Related articlesFree article

Relative resistance to nasally induced tolerance in non-obese diabetic mice but not other I-A(g7)-expressing mouse strains.

Quinn A, Melo M, Ethell D, Sercarz EE.

Int Immunol. 2001 Oct;13(10):1321-33.PMID: 11581177 [PubMed - indexed for MEDLINE]Related articlesFree article

I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice.

Noorchashm H, Lieu YK, Noorchashm N, Rostami SY, Greeley SA, Schlachterman A, Song HK, Noto LE, Jevnikar AM, Barker CF, Naji A.

J Immunol. 1999 Jul 15;163(2):743-50.PMID: 10395666 [PubMed - indexed for MEDLINE]Related articlesFree article

T-splenocytes from non-obese diabetic mice binding to xenogeneic pancreatic beta-cells in vitro. Implication of the alpha/beta T-cell receptor and of major histocompatibility complex class II molecules from target cells.

Martignat L, Feve B, Ouary M, Pogu S, Charbonnel B, Saï P.

J Autoimmun. 1993 Dec;6(6):753-69.PMID: 8155255 [PubMed - indexed for MEDLINE]Related articles

On the self-referential nature of naive MHC class II-restricted T cells.

Viret C, He X, Janeway CA Jr.

J Immunol. 2000 Dec 1;165(11):6183-92.PMID: 11086052 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of the role of variation of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response.

Ridgway WM, Ito H, Fassò M, Yu C, Fathman CG.

J Exp Med. 1998 Dec 21;188(12):2267-75.PMID: 9858513 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype.

Chen YG, Silveira PA, Osborne MA, Chapman HD, Serreze DV.

Diabetes. 2007 Feb;56(2):424-30.PMID: 17259387 [PubMed - indexed for MEDLINE]Related articlesFree article

Self major histocompatibility complex class I antigens expressed solely in lymphoid cells do not induce tolerance in the CD4+ T cell compartment.

Schulz R, Mellor AL.

J Exp Med. 1996 Oct 1;184(4):1573-8.PMID: 8879232 [PubMed - indexed for MEDLINE]Related articlesFree article

Weak positive selection of transgenic T cell receptor-bearing thymocytes: importance of major histocompatibility complex class II, T cell receptor and CD4 surface molecule densities.

Bogen B, Gleditsch L, Weiss S, Dembic Z.

Eur J Immunol. 1992 Mar;22(3):703-9.PMID: 1547816 [PubMed - indexed for MEDLINE]Related articles

Cross-positive selection of thymocytes expressing a single TCR by multiple major histocompatibility complex molecules of both classes: implications for CD4+ versus CD8+ lineage commitment.

Eshima K, Suzuki H, Shinohara N.

J Immunol. 2006 Feb 1;176(3):1628-36.PMID: 16424192 [PubMed - indexed for MEDLINE]Related articlesFree article

Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice.

Kanagawa O, Shimizu J, Vaupel BA.

J Immunol. 2000 May 15;164(10):5466-73.PMID: 10799914 [PubMed - indexed for MEDLINE]Related articlesFree article

In a transgenic model of spontaneous autoimmune diabetes, expression of a protective class II MHC molecule results in thymic deletion of diabetogenic CD8+ T cells.

Morgan DJ, Nugent CT, Raveney BJ, Sherman LA.

J Immunol. 2004 Jan 15;172(2):1000-8.PMID: 14707073 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoimmune tolerance and type 1 (insulin-dependent) diabetes mellitus.

Nossal GJ, Herold KC, Goodnow CC.

Diabetologia. 1992 Dec;35 Suppl 2:S49-59. Review.PMID: 1478378 [PubMed - indexed for MEDLINE]Related articles

Spontaneous T-cell proliferation in the non-obese diabetic mouse to a peptide from the unique class II MHC molecule, I-Ag7, which is also protective against the development of autoimmune diabetes.

Xu XJ, Gearon C, Stevens E, Vergani D, Baum H, Peakman M.

Diabetologia. 1999 May;42(5):560-5.PMID: 10333048 [PubMed - indexed for MEDLINE]Related articles