PubMed

Autocrine activation of the IGF-I signaling pathway in mesangial cells isolated from diabetic NOD mice.

Tack I, Elliot SJ, Potier M, Rivera A, Striker GE, Striker LJ.

Diabetes. 2002 Jan;51(1):182-8.PMID: 11756339 [PubMed - indexed for MEDLINE]Related articlesFree article

Autocrine activation of the local insulin-like growth factor I system is up-regulated by estrogen receptor (ER)-independent estrogen actions and accounts for decreased ER expression in type 2 diabetic mesangial cells.

Karl M, Potier M, Schulman IH, Rivera A, Werner H, Fornoni A, Elliot SJ.

Endocrinology. 2005 Feb;146(2):889-900. Epub 2004 Nov 18.PMID: 15550505 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.

Mur C, Valverde AM, Kahn CR, Benito M.

Diabetes. 2002 Mar;51(3):743-54.PMID: 11872675 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.

Qiao M, Shapiro P, Kumar R, Passaniti A.

J Biol Chem. 2004 Oct 8;279(41):42709-18. Epub 2004 Aug 9.PMID: 15304489 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells.

Halevy O, Cantley LC.

Exp Cell Res. 2004 Jul 1;297(1):224-34.PMID: 15194438 [PubMed - indexed for MEDLINE]Related articles

Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.

Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.

Diabetes. 2002 Apr;51(4):966-76.PMID: 11916914 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.

Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ.

Cancer Res. 2003 Jan 15;63(2):364-74.PMID: 12543789 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-1 decreases collagen degradation in diabetic NOD mesangial cells: implications for diabetic nephropathy.

Lupia E, Elliot SJ, Lenz O, Zheng F, Hattori M, Striker GE, Striker LJ.

Diabetes. 1999 Aug;48(8):1638-44.PMID: 10426384 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of IGF-I-induced Erk 1 and 2 activation and mitogenesis in mesangial cells by bradykinin.

Alric C, Pecher C, Cellier E, Schanstra JP, Poirier B, Chevalier J, Bascands JL, Girolami JP.

Kidney Int. 2002 Aug;62(2):412-21.PMID: 12110002 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of insulin-like growth factor (IGF) binding protein-3 synthesis by IGF-I and transforming growth factor-alpha is mediated by both phosphatidylinositol-3 kinase and mitogen-activated protein kinase pathways in mammary epithelial cells.

Sivaprasad U, Fleming J, Verma PS, Hogan KA, Desury G, Cohick WS.

Endocrinology. 2004 Sep;145(9):4213-21. Epub 2004 Jun 10.PMID: 15192040 [PubMed - indexed for MEDLINE]Related articlesFree article

Low insulin-like growth factor binding protein-2 expression is responsible for increased insulin receptor substrate-1 phosphorylation in mesangial cells from mice susceptible to glomerulosclerosis.

Fornoni A, Rosenzweig SA, Lenz O, Rivera A, Striker GE, Elliot SJ.

Endocrinology. 2006 Jul;147(7):3547-54. Epub 2006 Mar 23.PMID: 16556765 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3'-kinase/AKT signaling.

Tai YT, Podar K, Catley L, Tseng YH, Akiyama M, Shringarpure R, Burger R, Hideshima T, Chauhan D, Mitsiades N, Richardson P, Munshi NC, Kahn CR, Mitsiades C, Anderson KC.

Cancer Res. 2003 Sep 15;63(18):5850-8. Erratum in: Cancer Res. 2003 Nov 1;63(21):7543. PMID: 14522909 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.

Andreozzi F, Laratta E, Sciacqua A, Perticone F, Sesti G.

Circ Res. 2004 May 14;94(9):1211-8. Epub 2004 Mar 25.PMID: 15044323 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth factor-specific regulation of insulin receptor substrate-1 expression in MCF-7 breast carcinoma cells: effects on the insulin-like growth factor signaling pathway.

Lassarre C, Ricort JM.

Endocrinology. 2003 Nov;144(11):4811-9. Epub 2003 Jul 24.PMID: 12960057 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-I is an autocrine regulator of chromogranin A secretion and growth in human neuroendocrine tumor cells.

von Wichert G, Jehle PM, Hoeflich A, Koschnick S, Dralle H, Wolf E, Wiedenmann B, Boehm BO, Adler G, Seufferlein T.

Cancer Res. 2000 Aug 15;60(16):4573-81.PMID: 10969809 [PubMed - indexed for MEDLINE]Related articlesFree article

ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation.

Morrison KB, Tognon CE, Garnett MJ, Deal C, Sorensen PH.

Oncogene. 2002 Aug 22;21(37):5684-95.PMID: 12173038 [PubMed - indexed for MEDLINE]Related articlesFree article

Extracellular signal-regulated kinase-1 and -2 respond differently to mitogenic and differentiative signaling pathways in myoblasts.

Sarbassov DD, Jones LG, Peterson CA.

Mol Endocrinol. 1997 Dec;11(13):2038-47.PMID: 9415407 [PubMed - indexed for MEDLINE]Related articlesFree article

RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix.

Hermanto U, Zong CS, Li W, Wang LH.

Mol Cell Biol. 2002 Apr;22(7):2345-65.PMID: 11884618 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1).

Wrede CE, Dickson LM, Lingohr MK, Briaud I, Rhodes CJ.

J Mol Endocrinol. 2003 Jun;30(3):271-86.PMID: 12790799 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1.

Dalle S, Imamura T, Rose DW, Worrall DS, Ugi S, Hupfeld CJ, Olefsky JM.

Mol Cell Biol. 2002 Sep;22(17):6272-85.PMID: 12167719 [PubMed - indexed for MEDLINE]Related articlesFree article