PubMed

Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway.

Vecchione C, Maffei A, Colella S, Aretini A, Poulet R, Frati G, Gentile MT, Fratta L, Trimarco V, Trimarco B, Lembo G.

Diabetes. 2002 Jan;51(1):168-73.PMID: 11756337 [PubMed - indexed for MEDLINE]Related articlesFree article

Reciprocal phosphorylation and regulation of endothelial nitric-oxide synthase in response to bradykinin stimulation.

Harris MB, Ju H, Venema VJ, Liang H, Zou R, Michell BJ, Chen ZP, Kemp BE, Venema RC.

J Biol Chem. 2001 May 11;276(19):16587-91. Epub 2001 Feb 28.PMID: 11340086 [PubMed - indexed for MEDLINE]Related articlesFree article

Akt-dependent phosphorylation of serine 1179 and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase 1/2 cooperatively mediate activation of the endothelial nitric-oxide synthase by hydrogen peroxide.

Cai H, Li Z, Davis ME, Kanner W, Harrison DG, Dudley SC Jr.

Mol Pharmacol. 2003 Feb;63(2):325-31.PMID: 12527803 [PubMed - indexed for MEDLINE]Related articlesFree article

Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells.

Haynes MP, Sinha D, Russell KS, Collinge M, Fulton D, Morales-Ruiz M, Sessa WC, Bender JR.

Circ Res. 2000 Oct 13;87(8):677-82.PMID: 11029403 [PubMed - indexed for MEDLINE]Related articlesFree article

Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways.

Gélinas DS, Bernatchez PN, Rollin S, Bazan NG, Sirois MG.

Br J Pharmacol. 2002 Dec;137(7):1021-30.PMID: 12429574 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

Chen H, Montagnani M, Funahashi T, Shimomura I, Quon MJ.

J Biol Chem. 2003 Nov 7;278(45):45021-6. Epub 2003 Aug 27.PMID: 12944390 [PubMed - indexed for MEDLINE]Related articlesFree article

Pregnancy-enhanced endothelial nitric oxide synthase (eNOS) activation in uterine artery endothelial cells shows altered sensitivity to Ca2+, U0126, and wortmannin but not LY294002--evidence that pregnancy adaptation of eNOS activation occurs at multiple levels of cell signaling.

Sullivan JA, Grummer MA, Yi FX, Bird IM.

Endocrinology. 2006 May;147(5):2442-57. Epub 2006 Feb 2.PMID: 16455784 [PubMed - indexed for MEDLINE]Related articlesFree article

The inhibitory effect of leptin on angiotensin II-induced vasoconstriction in vascular smooth muscle cells is mediated via a nitric oxide-dependent mechanism.

Rodríguez A, Fortuño A, Gómez-Ambrosi J, Zalba G, Díez J, Frühbeck G.

Endocrinology. 2007 Jan;148(1):324-31. Epub 2006 Oct 12.PMID: 17038553 [PubMed - indexed for MEDLINE]Related articlesFree article

Genistein acutely stimulates nitric oxide synthesis in vascular endothelial cells by a cyclic adenosine 5'-monophosphate-dependent mechanism.

Liu D, Homan LL, Dillon JS.

Endocrinology. 2004 Dec;145(12):5532-9. Epub 2004 Aug 19.PMID: 15319357 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation.

Gao F, Gao E, Yue TL, Ohlstein EH, Lopez BL, Christopher TA, Ma XL.

Circulation. 2002 Mar 26;105(12):1497-502.PMID: 11914261 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of shear stress-induced endothelial nitric-oxide synthase phosphorylation and expression in ovine fetoplacental artery endothelial cells.

Li Y, Zheng J, Bird IM, Magness RR.

Biol Reprod. 2004 Mar;70(3):785-96. Epub 2003 Nov 19.PMID: 14627548 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide-dependent beta2-adrenergic dilatation of rat aorta is mediated through activation of both protein kinase A and Akt.

Ferro A, Coash M, Yamamoto T, Rob J, Ji Y, Queen L.

Br J Pharmacol. 2004 Oct;143(3):397-403. Epub 2004 Sep 6.PMID: 15351777 [PubMed - indexed for MEDLINE]Related articlesFree article

Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A.

Boo YC, Sorescu G, Boyd N, Shiojima I, Walsh K, Du J, Jo H.

J Biol Chem. 2002 Feb 1;277(5):3388-96. Epub 2001 Nov 29.PMID: 11729190 [PubMed - indexed for MEDLINE]Related articlesFree article

High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases.

Mineo C, Yuhanna IS, Quon MJ, Shaul PW.

J Biol Chem. 2003 Mar 14;278(11):9142-9. Epub 2003 Jan 2.PMID: 12511559 [PubMed - indexed for MEDLINE]Related articlesFree article

Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection.

Hurt KJ, Musicki B, Palese MA, Crone JK, Becker RE, Moriarity JL, Snyder SH, Burnett AL.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):4061-6.PMID: 11904450 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of phosphatidylinositol 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects of rapamycin, Ly294002, and wortmannin on nitric oxide production.

Salh B, Wagey R, Marotta A, Tao JS, Pelech S.

J Immunol. 1998 Dec 15;161(12):6947-54.PMID: 9862729 [PubMed - indexed for MEDLINE]Related articlesFree article

Reconstituted high-density lipoprotein inhibits thrombin-induced endothelial tissue factor expression through inhibition of RhoA and stimulation of phosphatidylinositol 3-kinase but not Akt/endothelial nitric oxide synthase.

Viswambharan H, Ming XF, Zhu S, Hubsch A, Lerch P, Vergères G, Rusconi S, Yang Z.

Circ Res. 2004 Apr 16;94(7):918-25. Epub 2004 Feb 26.PMID: 14988229 [PubMed - indexed for MEDLINE]Related articlesFree article

Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells.

Jin ZG, Wong C, Wu J, Berk BC.

J Biol Chem. 2005 Apr 1;280(13):12305-9. Epub 2005 Jan 21.PMID: 15665327 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte growth factor stimulates nitric oxide production through endothelial nitric oxide synthase activation by the phosphoinositide 3-kinase/Akt pathway and possibly by mitogen-activated protein kinase kinase in vascular endothelial cells.

Uruno A, Sugawara A, Kanatsuka H, Arima S, Taniyama Y, Kudo M, Takeuchi K, Ito S.

Hypertens Res. 2004 Nov;27(11):887-95.PMID: 15824471 [PubMed - indexed for MEDLINE]Related articlesFree article

17-beta-oestradiol-induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism.

Bucci M, Roviezzo F, Cicala C, Pinto A, Cirino G.

Br J Pharmacol. 2002 Apr;135(7):1695-700.PMID: 11934809 [PubMed - indexed for MEDLINE]Related articlesFree article