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Intrahepatic mechanisms underlying the effect of metformin in decreasing basal glucose production in rats fed a high-fat diet.

Mithieux G, Guignot L, Bordet JC, Wiernsperger N.

Diabetes. 2002 Jan;51(1):139-43.PMID: 11756333 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of glucose-6 phosphatase, glucokinase, and glucose-6 phosphate in liver insulin resistance and its correction by metformin.

Minassian C, Tarpin S, Mithieux G.

Biochem Pharmacol. 1998 Apr 15;55(8):1213-9.PMID: 9719475 [PubMed - indexed for MEDLINE]Related articles

Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin.

Song S, Andrikopoulos S, Filippis C, Thorburn AW, Khan D, Proietto J.

Am J Physiol Endocrinol Metab. 2001 Aug;281(2):E275-82.PMID: 11440903 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus.

Cusi K, Consoli A, DeFronzo RA.

J Clin Endocrinol Metab. 1996 Nov;81(11):4059-67.PMID: 8923861 [PubMed - indexed for MEDLINE]Related articles

Glucose utilization is suppressed in the gut of insulin-resistant high fat-fed rats and is restored by metformin.

Mithieux G, Rajas F, Zitoun C.

Biochem Pharmacol. 2006 Dec 15;72(12):1757-62.PMID: 17195303 [PubMed - indexed for MEDLINE]Related articles

Glucose utilization is suppressed in the gut of insulin-resistant high fat-fed rats and is restored by metformin.

Mithieux G, Rajas F, Zitoun C.

Biochem Pharmacol. 2006 Jul 14;72(2):198-203. Epub 2006 May 2. Erratum in: Biochem Pharmacol. 2006 Dec 15;72(12):1756. Biochem Pharmacol. 2006 Nov 15;72(10):1354. Corrected and republished in: Biochem Pharmacol. 2006 Dec 15;72(12):1757-62. PMID: 16737687 [PubMed - indexed for MEDLINE]Related articles

Glucosamine-induced inhibition of liver glucokinase impairs the ability of hyperglycemia to suppress endogenous glucose production.

Barzilai N, Hawkins M, Angelov I, Hu M, Rossetti L.

Diabetes. 1996 Oct;45(10):1329-35.PMID: 8826967 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding.

Oakes ND, Cooney GJ, Camilleri S, Chisholm DJ, Kraegen EW.

Diabetes. 1997 Nov;46(11):1768-74.PMID: 9356024 [PubMed - indexed for MEDLINE]Related articles

[Effects of rosiglitazone and metformin on insulin resistance in high-fat diet rats]

Chen XP, Yang WY, Bu S, Xiao JZ, Liu XL, Wang N, Zhao WH.

Zhonghua Nei Ke Za Zhi. 2004 Apr;43(4):280-3. Chinese. PMID: 15130413 [PubMed - indexed for MEDLINE]Related articles

Comparison of the effects of pioglitazone and metformin on hepatic and extra-hepatic insulin action in people with type 2 diabetes.

Basu R, Shah P, Basu A, Norby B, Dicke B, Chandramouli V, Cohen O, Landau BR, Rizza RA.

Diabetes. 2008 Jan;57(1):24-31. Epub 2007 Oct 3.PMID: 17914032 [PubMed - indexed for MEDLINE]Related articlesFree article

High-fat- and lipid-induced insulin resistance in rats: the comparison of glucose metabolism, plasma resistin and adiponectin levels.

Li L, Yang G, Li Q, Tang Y, Li K.

Ann Nutr Metab. 2006;50(6):499-505. Epub 2006 Dec 21.PMID: 17191023 [PubMed - indexed for MEDLINE]Related articles

Effect of masoprocol on carbohydrate and lipid metabolism in a rat model of Type II diabetes.

Reed MJ, Meszaros K, Entes LJ, Claypool MD, Pinkett JG, Brignetti D, Luo J, Khandwala A, Reaven GM.

Diabetologia. 1999 Jan;42(1):102-6.PMID: 10027587 [PubMed - indexed for MEDLINE]Related articles

Diets enriched in sucrose or fat increase gluconeogenesis and G-6-Pase but not basal glucose production in rats.

Commerford SR, Ferniza JB, Bizeau ME, Thresher JS, Willis WT, Pagliassotti MJ.

Am J Physiol Endocrinol Metab. 2002 Sep;283(3):E545-55.PMID: 12169448 [PubMed - indexed for MEDLINE]Related articlesFree article

Arachidonic acid can significantly prevent early insulin resistance induced by a high-fat diet.

Wu M, Wang X, Duan Q, Lu T.

Ann Nutr Metab. 2007;51(3):270-6. Epub 2007 Jul 9.PMID: 17622786 [PubMed - indexed for MEDLINE]Related articles

Mealtime 50/50 basal + prandial insulin analogue mixture with a basal insulin analogue, both plus metformin, in the achievement of target HbA1c and pre- and postprandial blood glucose levels in patients with type 2 diabetes: a multinational, 24-week, randomized, open-label, parallel-group comparison.

Robbins DC, Beisswenger PJ, Ceriello A, Goldberg RB, Moses RG, Pagkalos EM, Milicevic Z, Jones CA, Sarwat S, Tan MH.

Clin Ther. 2007 Nov;29(11):2349-64.PMID: 18158076 [PubMed - indexed for MEDLINE]Related articles

Effects of metformin on lactate uptake and gluconeogenesis in the perfused rat liver.

Radziuk J, Zhang Z, Wiernsperger N, Pye S.

Diabetes. 1997 Sep;46(9):1406-13.PMID: 9287039 [PubMed - indexed for MEDLINE]Related articles

[The mechanism of and relationship between lipid metabolism genes expression and insulin resistance in high fat-fed mice]

Bai XP, Li HL, Yang WY, Xiao JZ, Wang B, Du RQ, Lou DJ.

Zhonghua Nei Ke Za Zhi. 2007 Sep;46(9):751-4. Chinese. PMID: 18028806 [PubMed - indexed for MEDLINE]Related articles

Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes.

Rossetti L, Giaccari A, Barzilai N, Howard K, Sebel G, Hu M.

J Clin Invest. 1993 Sep;92(3):1126-34.PMID: 8397219 [PubMed - indexed for MEDLINE]Related articlesFree article

Depolarization of the liver cell membrane by metformin.

Lutz TA, Estermann A, Haag S, Scharrer E.

Biochim Biophys Acta. 2001 Aug 6;1513(2):176-84.PMID: 11470089 [PubMed - indexed for MEDLINE]Related articles

The acute effect of metformin on glucose production in the conscious dog is primarily attributable to inhibition of glycogenolysis.

Chu CA, Wiernsperger N, Muscato N, Knauf M, Neal DW, Cherrington AD.

Metabolism. 2000 Dec;49(12):1619-26.PMID: 11145127 [PubMed - indexed for MEDLINE]Related articles