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A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion.
Persaud SJ, Roderigo-Milne HM, Squires PE, Sugden D, Wheeler-Jones CP, Marsh PJ, Belin VD, Luther MJ, Jones PM.
Diabetes. 2002 Jan;51(1):98-104.PMID: 11756328 [PubMed - indexed for MEDLINE]Related articlesFree article
Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A(2).
Milne HM, Burns CJ, Squires PE, Evans ND, Pickup J, Jones PM, Persaud SJ.
Diabetes. 2005 Jan;54(1):116-24.PMID: 15616018 [PubMed - indexed for MEDLINE]Related articlesFree article
The role of cytosolic phospholipase A(2) in insulin secretion.
Jones PM, Burns CJ, Belin VD, Roderigo-Milne HM, Persaud SJ.
Diabetes. 2004 Feb;53 Suppl 1:S172-8.PMID: 14749284 [PubMed - indexed for MEDLINE]Related articlesFree article
Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.
da Silva Xavier G, Varadi A, Ainscow EK, Rutter GA.
J Biol Chem. 2000 Nov 17;275(46):36269-77.PMID: 10967119 [PubMed - indexed for MEDLINE]Related articlesFree article
Effect of 17beta-estradiol on insulin secretion and cytosolic calcium in Min6 mouse insulinoma cells and human islets of Langerhans.
Al-Majed HT, Squires PE, Persaud SJ, Huang GC, Amiel S, Whitehouse BJ, Jones PM.
Pancreas. 2005 May;30(4):307-13.PMID: 15841038 [PubMed - indexed for MEDLINE]Related articles
A buffer temperature controlled perifusion system to study temperature dependence and kinetics of insulin secretion in MIN6 pseudoislets.
Brenner MB, Mest HJ.
J Pharmacol Toxicol Methods. 2004 Jul-Aug;50(1):53-7.PMID: 15233968 [PubMed - indexed for MEDLINE]Related articles
Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from MIN6 and HIT cells.
Ishihara H, Nakazaki M, Kanegae Y, Inukai K, Asano T, Katagiri H, Yazaki Y, Kikuchi M, Miyazaki J, Saito I, Oka Y.
Diabetes. 1996 Sep;45(9):1238-44.PMID: 8772729 [PubMed - indexed for MEDLINE]Related articles
Calcium-dependent translocation of cytosolic phospholipase A2 in pancreatic beta-cells.
Persaud SJ, Jones PM, Roderigo-Milne HM, Buchan AM, Squires PE.
Biochem Biophys Res Commun. 2003 Jan 24;300(4):889-93.PMID: 12559956 [PubMed - indexed for MEDLINE]Related articles
Synchronization of Ca(2+)-signals within insulin-secreting pseudoislets: effects of gap-junctional uncouplers.
Squires PE, Hauge-Evans AC, Persaud SJ, Jones PM.
Cell Calcium. 2000 May;27(5):287-96.PMID: 10859595 [PubMed - indexed for MEDLINE]Related articles
Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression.
da Silva Xavier G, Leclerc I, Varadi A, Tsuboi T, Moule SK, Rutter GA.
Biochem J. 2003 May 1;371(Pt 3):761-74.PMID: 12589707 [PubMed - indexed for MEDLINE]Related articlesFree article
Role of adenine nucleotides in insulin secretion from MIN6 pseudoislets.
Hauge-Evans AC, Squires PE, Belin VD, Roderigo-Milne H, Ramracheya RD, Persaud SJ, Jones PM.
Mol Cell Endocrinol. 2002 Jun 14;191(2):167-76.PMID: 12062900 [PubMed - indexed for MEDLINE]Related articles
Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans.
Ramracheya RD, Muller DS, Wu Y, Whitehouse BJ, Huang GC, Amiel SA, Karalliedde J, Viberti G, Jones PM, Persaud SJ.
Diabetologia. 2006 Feb;49(2):321-31. Epub 2006 Jan 17.PMID: 16416272 [PubMed - indexed for MEDLINE]Related articles
ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans.
Al-Majed HT, Jones PM, Persaud SJ, Sugden D, Huang GC, Amiel S, Whitehouse BJ.
J Endocrinol. 2004 Jan;180(1):155-66.PMID: 14709154 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucose-induced preproinsulin gene expression is inhibited by the free fatty acid palmitate.
Ritz-Laser B, Meda P, Constant I, Klages N, Charollais A, Morales A, Magnan C, Ktorza A, Philippe J.
Endocrinology. 1999 Sep;140(9):4005-14.PMID: 10465270 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucose-regulated glucagon secretion requires insulin receptor expression in pancreatic alpha-cells.
Diao J, Asghar Z, Chan CB, Wheeler MB.
J Biol Chem. 2005 Sep 30;280(39):33487-96. Epub 2005 Jul 14.PMID: 16027126 [PubMed - indexed for MEDLINE]Related articlesFree article
Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for iPLA2beta.
Ma Z, Ramanadham S, Wohltmann M, Bohrer A, Hsu FF, Turk J.
J Biol Chem. 2001 Apr 20;276(16):13198-208. Epub 2001 Jan 22.PMID: 11278673 [PubMed - indexed for MEDLINE]Related articlesFree article
Kinetics of insulin secretion from MIN6 pseudoislets after encapsulation in a prototype device of a bioartificial pancreas.
Barrientos R, Baltrusch S, Sigrist S, Legeay G, Belcourt A, Lenzen S.
Horm Metab Res. 2009 Jan;41(1):5-9. Epub 2008 Oct 14.PMID: 18855306 [PubMed - indexed for MEDLINE]Related articles
Overexpression of hexokinase I but not GLUT1 glucose transporter alters concentration dependence of glucose-stimulated insulin secretion in pancreatic beta-cell line MIN6.
Ishihara H, Asano T, Tsukuda K, Katagiri H, Inukai K, Anai M, Kikuchi M, Yazaki Y, Miyazaki J, Oka Y.
J Biol Chem. 1994 Jan 28;269(4):3081-7.PMID: 8300643 [PubMed - indexed for MEDLINE]Related articlesFree article
Proprotein-processing endoprotease furin decreases regulated secretory pathway-specific proteins in the pancreatic beta cell line MIN6.
Kayo T, Sawada Y, Suzuki Y, Suda M, Tanaka S, Konda Y, Miyazaki J, Takeuchi T.
J Biol Chem. 1996 May 3;271(18):10731-7.PMID: 8631882 [PubMed - indexed for MEDLINE]Related articlesFree article
Connexin 36 controls synchronization of Ca2+ oscillations and insulin secretion in MIN6 cells.
Calabrese A, Zhang M, Serre-Beinier V, Caton D, Mas C, Satin LS, Meda P.
Diabetes. 2003 Feb;52(2):417-24.PMID: 12540616 [PubMed - indexed for MEDLINE]Related articlesFree article
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