PubMed

Phosphatidylinositol 3-kinase redistribution is associated with skeletal muscle insulin resistance in gestational diabetes mellitus.

Shao J, Yamashita H, Qiao L, Draznin B, Friedman JE.

Diabetes. 2002 Jan;51(1):19-29.PMID: 11756318 [PubMed - indexed for MEDLINE]Related articlesFree article

Human placental growth hormone increases expression of the p85 regulatory unit of phosphatidylinositol 3-kinase and triggers severe insulin resistance in skeletal muscle.

Barbour LA, Shao J, Qiao L, Leitner W, Anderson M, Friedman JE, Draznin B.

Endocrinology. 2004 Mar;145(3):1144-50. Epub 2003 Nov 21.PMID: 14633976 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice.

Shao J, Yamashita H, Qiao L, Friedman JE.

J Endocrinol. 2000 Oct;167(1):107-15.PMID: 11018758 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats.

Song XM, Kawano Y, Krook A, Ryder JW, Efendic S, Roth RA, Wallberg-Henriksson H, Zierath JR.

Diabetes. 1999 Mar;48(3):664-70.PMID: 10078575 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: differential effects on insulin-receptor substrates 1 and 2.

Chibalin AV, Yu M, Ryder JW, Song XM, Galuska D, Krook A, Wallberg-Henriksson H, Zierath JR.

Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):38-43.PMID: 10618367 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation.

Tirosh A, Potashnik R, Bashan N, Rudich A.

J Biol Chem. 1999 Apr 9;274(15):10595-602.PMID: 10187855 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise.

Beeson M, Sajan MP, Dizon M, Grebenev D, Gomez-Daspet J, Miura A, Kanoh Y, Powe J, Bandyopadhyay G, Standaert ML, Farese RV.

Diabetes. 2003 Aug;52(8):1926-34.PMID: 12882907 [PubMed - indexed for MEDLINE]Related articlesFree article

The Gly-->Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells.

Hribal ML, Federici M, Porzio O, Lauro D, Borboni P, Accili D, Lauro R, Sesti G.

J Clin Endocrinol Metab. 2000 May;85(5):2004-13.PMID: 10843189 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities.

Tremblay F, Lavigne C, Jacques H, Marette A.

Diabetes. 2001 Aug;50(8):1901-10.PMID: 11473054 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance.

Kim JA, Yeh DC, Ver M, Li Y, Carranza A, Conrads TP, Veenstra TD, Harrington MA, Quon MJ.

J Biol Chem. 2005 Jun 17;280(24):23173-83. Epub 2005 Apr 22.PMID: 15849359 [PubMed - indexed for MEDLINE]Related articlesFree article

Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake.

Storz P, Döppler H, Wernig A, Pfizenmaier K, Müller G.

Eur J Biochem. 1999 Nov;266(1):17-25.PMID: 10542046 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced glucose uptake precedes insulin signaling defects in adipocytes from heterozygous GLUT4 knockout mice.

Li J, Houseknecht KL, Stenbit AE, Katz EB, Charron MJ.

FASEB J. 2000 Jun;14(9):1117-25.PMID: 10834933 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.

Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E194-9. Epub 2004 Aug 31.PMID: 15339744 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of overexpression of human GLUT4 gene on maternal diabetes and fetal growth in spontaneous gestational diabetic C57BLKS/J Lepr(db/+) mice.

Ishizuka T, Klepcyk P, Liu S, Panko L, Liu S, Gibbs EM, Friedman JE.

Diabetes. 1999 May;48(5):1061-9.PMID: 10331411 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatidylinositol 4-kinase, but not phosphatidylinositol 3-kinase, is present in GLUT4-containing vesicles isolated from rat skeletal muscle.

Kristiansen S, Ramlal T, Klip A.

Biochem J. 1998 Oct 15;335 ( Pt 2):351-6.PMID: 9761734 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired glucose transport and insulin receptor tyrosine phosphorylation in skeletal muscle from obese women with gestational diabetes.

Friedman JE, Ishizuka T, Shao J, Huston L, Highman T, Catalano P.

Diabetes. 1999 Sep;48(9):1807-14.PMID: 10480612 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of whole-body and skeletal muscle insulin resistance after one day of hindlimb suspension.

O'keefe MP, Perez FR, Kinnick TR, Tischler ME, Henriksen EJ.

Metabolism. 2004 Sep;53(9):1215-22.PMID: 15334387 [PubMed - indexed for MEDLINE]Related articles

Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells.

Tremblay F, Marette A.

J Biol Chem. 2001 Oct 12;276(41):38052-60. Epub 2001 Aug 9.PMID: 11498541 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of improving effect of losartan on insulin sensitivity of non-insulin-dependent diabetes mellitus rats.

Wu Y, Ouyang JP, Zhou YF, Wu K, Zhao DH, Wen CY.

Sheng Li Xue Bao. 2004 Aug 25;56(4):539-49.PMID: 15322693 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary cod protein restores insulin-induced activation of phosphatidylinositol 3-kinase/Akt and GLUT4 translocation to the T-tubules in skeletal muscle of high-fat-fed obese rats.

Tremblay F, Lavigne C, Jacques H, Marette A.

Diabetes. 2003 Jan;52(1):29-37.PMID: 12502490 [PubMed - indexed for MEDLINE]Related articlesFree article