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    Results: 1 to 20 of 90

    1.

    Update on HER-2 as a target for cancer therapy: intracellular signaling pathways of ErbB2/HER-2 and family members.

    Olayioye MA.

    Breast Cancer Res. 2001;3(6):385-9. Epub 2001 Oct 4. Review.

    PMID:
    11737890
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Complexity of signal transduction mediated by ErbB2: clues to the potential of receptor-targeted cancer therapy.

    Nagy P, Jenei A, Damjanovich S, Jovin TM, Szölôsi J.

    Pathol Oncol Res. 1999;5(4):255-71. Review.

    PMID:
    10607920
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    Dysregulation of cellular signaling by HER2/neu in breast cancer.

    Zhou BP, Hung MC.

    Semin Oncol. 2003 Oct;30(5 Suppl 16):38-48. Review.

    PMID:
    14613025
    [PubMed - indexed for MEDLINE]
    4.

    Potential benefits of the irreversible pan-erbB inhibitor, CI-1033, in the treatment of breast cancer.

    Allen LF, Lenehan PF, Eiseman IA, Elliott WL, Fry DW.

    Semin Oncol. 2002 Jun;29(3 Suppl 11):11-21. Review.

    PMID:
    12138393
    [PubMed - indexed for MEDLINE]
    5.

    Update on HER-2 as a target for cancer therapy: the ERBB2 promoter and its exploitation for cancer treatment.

    Hurst HC.

    Breast Cancer Res. 2001;3(6):395-8. Epub 2001 Oct 1. Review.

    PMID:
    11737892
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    The ErbB2 signaling network as a target for breast cancer therapy.

    Badache A, Gonçalves A.

    J Mammary Gland Biol Neoplasia. 2006 Jan;11(1):13-25. Review.

    PMID:
    16947083
    [PubMed - indexed for MEDLINE]
    7.

    The achilles heel of ErbB-2/HER2: regulation by the Hsp90 chaperone machine and potential for pharmacological intervention.

    Citri A, Kochupurakkal BS, Yarden Y.

    Cell Cycle. 2004 Jan;3(1):51-60. Review.

    PMID:
    14657666
    [PubMed - indexed for MEDLINE]
    Free Article
    8.

    HER-2 and NF-kappaB as the targets for therapy-resistant breast cancer.

    Ahmed KM, Cao N, Li JJ.

    Anticancer Res. 2006 Nov-Dec;26(6B):4235-43. Review.

    PMID:
    17201139
    [PubMed - indexed for MEDLINE]
    9.

    HER-2 signaling and inhibition in breast cancer.

    Browne BC, O'Brien N, Duffy MJ, Crown J, O'Donovan N.

    Curr Cancer Drug Targets. 2009 May;9(3):419-38. Review.

    PMID:
    19442060
    [PubMed - indexed for MEDLINE]
    10.

    Differential regulation of ErbB2 expression by cAMP-dependent protein kinase in tamoxifen-resistant breast cancer cells.

    Yang JW, Kim MR, Kim HG, Kim SK, Jeong HG, Kang KW.

    Arch Pharm Res. 2008 Mar;31(3):350-6. Epub 2008 Apr 13.

    PMID:
    18409049
    [PubMed - indexed for MEDLINE]
    11.

    Advances in targeting human epidermal growth factor receptor-2 signaling for cancer therapy.

    Meric-Bernstam F, Hung MC.

    Clin Cancer Res. 2006 Nov 1;12(21):6326-30. Review.

    PMID:
    17085641
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    An update of the mechanisms of resistance to EGFR-tyrosine kinase inhibitors in breast cancer: Gefitinib (Iressa) -induced changes in the expression and nucleo-cytoplasmic trafficking of HER-ligands (Review).

    Ferrer-Soler L, Vazquez-Martin A, Brunet J, Menendez JA, De Llorens R, Colomer R.

    Int J Mol Med. 2007 Jul;20(1):3-10. Review.

    PMID:
    17549382
    [PubMed - indexed for MEDLINE]
    13.

    Lipid rafts and the local density of ErbB proteins influence the biological role of homo- and heteroassociations of ErbB2.

    Nagy P, Vereb G, Sebestyén Z, Horváth G, Lockett SJ, Damjanovich S, Park JW, Jovin TM, Szöllosi J.

    J Cell Sci. 2002 Nov 15;115(Pt 22):4251-62.

    PMID:
    12376557
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer.

    Stern DF.

    J Mammary Gland Biol Neoplasia. 2008 Jun;13(2):215-23. Epub 2008 May 3. Review.

    PMID:
    18454306
    [PubMed - indexed for MEDLINE]
    16.

    Targeting the HER-kinase axis in cancer.

    Gross ME, Shazer RL, Agus DB.

    Semin Oncol. 2004 Feb;31(1 Suppl 3):9-20. Review.

    PMID:
    15052539
    [PubMed - indexed for MEDLINE]
    17.

    Receptor-targeted cancer therapy.

    Richter M, Zhang H.

    DNA Cell Biol. 2005 May;24(5):271-82. Review.

    PMID:
    15869404
    [PubMed - indexed for MEDLINE]
    18.

    Beyond trastuzumab: overcoming resistance to targeted HER-2 therapy in breast cancer.

    Bedard PL, de Azambuja E, Cardoso F.

    Curr Cancer Drug Targets. 2009 Mar;9(2):148-62. Review.

    PMID:
    19275756
    [PubMed - indexed for MEDLINE]
    19.

    HER (erbB) tyrosine kinase inhibitors in the treatment of breast cancer.

    Arteaga CL, Moulder SL, Yakes FM.

    Semin Oncol. 2002 Jun;29(3 Suppl 11):4-10. Review.

    PMID:
    12138392
    [PubMed - indexed for MEDLINE]
    20.

    Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin.

    Anastasi S, Sala G, Huiping C, Caprini E, Russo G, Iacovelli S, Lucini F, Ingvarsson S, Segatto O.

    Oncogene. 2005 Jun 30;24(28):4540-8.

    PMID:
    15856022
    [PubMed - indexed for MEDLINE]

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