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    Results: 1 to 20 of 318

    1.

    PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.

    Guerre-Millo M, Rouault C, Poulain P, André J, Poitout V, Peters JM, Gonzalez FJ, Fruchart JC, Reach G, Staels B.

    Diabetes. 2001 Dec;50(12):2809-14.PMID: 11723064 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Peroxisome proliferator-activated receptor-alpha deficiency does not alter insulin sensitivity in mice maintained on regular or high-fat diet: hyperinsulinemic-euglycemic clamp studies.

    Haluzik M, Gavrilova O, LeRoith D.

    Endocrinology. 2004 Apr;145(4):1662-7. Epub 2003 Dec 11.PMID: 14670996 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Increased glucose tolerance in N-type Ca2+ channel alpha(1B)-subunit gene-deficient mice.

    Takahashi E, Ito M, Miyamoto N, Nagasu T, Ino M, Tanaka I.

    Int J Mol Med. 2005 Jun;15(6):937-44.PMID: 15870896 [PubMed - indexed for MEDLINE]Related articles

    4.

    Peroxisome proliferator-activated receptor-alpha deficiency protects aged mice from insulin resistance induced by high-fat diet.

    Cha DR, Han JY, Su DM, Zhang Y, Fan X, Breyer MD, Guan Y.

    Am J Nephrol. 2007;27(5):479-82. Epub 2007 Jul 25.PMID: 17652964 [PubMed - indexed for MEDLINE]Related articles

    5.

    Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose production.

    Xu J, Xiao G, Trujillo C, Chang V, Blanco L, Joseph SB, Bassilian S, Saad MF, Tontonoz P, Lee WN, Kurland IJ.

    J Biol Chem. 2002 Dec 27;277(52):50237-44. Epub 2002 Aug 9.PMID: 12176975 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Selective modification of pyruvate dehydrogenase kinase isoform expression in rat pancreatic islets elicited by starvation and activation of peroxisome proliferator-activated receptor-alpha: implications for glucose-stimulated insulin secretion.

    Sugden MC, Bulmer K, Augustine D, Holness MJ.

    Diabetes. 2001 Dec;50(12):2729-36.PMID: 11723055 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation.

    Ye JM, Doyle PJ, Iglesias MA, Watson DG, Cooney GJ, Kraegen EW.

    Diabetes. 2001 Feb;50(2):411-7.PMID: 11272155 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice.

    Ahrén B, Simonsson E, Scheurink AJ, Mulder H, Myrsén U, Sundler F.

    Metabolism. 1997 Jan;46(1):97-106.PMID: 9005977 [PubMed - indexed for MEDLINE]Related articles

    9.

    Acute (24 h) activation of peroxisome proliferator-activated receptor-alpha (PPARalpha) reverses high-fat feeding-induced insulin hypersecretion in vivo and in perifused pancreatic islets.

    Holness MJ, Smith ND, Greenwood GK, Sugden MC.

    J Endocrinol. 2003 May;177(2):197-205.PMID: 12740007 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner.

    Neschen S, Morino K, Dong J, Wang-Fischer Y, Cline GW, Romanelli AJ, Rossbacher JC, Moore IK, Regittnig W, Munoz DS, Kim JH, Shulman GI.

    Diabetes. 2007 Apr;56(4):1034-41. Epub 2007 Jan 24.PMID: 17251275 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones.

    Norris AW, Chen L, Fisher SJ, Szanto I, Ristow M, Jozsi AC, Hirshman MF, Rosen ED, Goodyear LJ, Gonzalez FJ, Spiegelman BM, Kahn CR.

    J Clin Invest. 2003 Aug;112(4):608-18.PMID: 12925701 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet.

    Nunemaker CS, Chen M, Pei H, Kimble SD, Keller SR, Carter JD, Yang Z, Smith KM, Wu R, Bevard MH, Garmey JC, Nadler JL.

    Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1065-75. Epub 2008 Sep 9.PMID: 18780776 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Increased insulin secretion and normalization of glucose tolerance by cholinergic agonism in high fat-fed mice.

    Ahrén B, Sauerberg P, Thomsen C.

    Am J Physiol. 1999 Jul;277(1 Pt 1):E93-102.PMID: 10409132 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Potential role of peroxisome proliferator-activated receptor-alpha in the modulation of glucose-stimulated insulin secretion.

    Sugden MC, Holness MJ.

    Diabetes. 2004 Feb;53 Suppl 1:S71-81. Review.PMID: 14749269 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Altered beta-cell distribution of pdx-1 and GLUT-2 after a short-term challenge with a high-fat diet in C57BL/6J mice.

    Reimer MK, Ahrén B.

    Diabetes. 2002 Feb;51 Suppl 1:S138-43.PMID: 11815473 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.

    Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, Way JM, Winegar DA, Corton JC, Dohm GL, Kraus WE.

    J Biol Chem. 2002 Jul 19;277(29):26089-97. Epub 2002 May 6.PMID: 12118038 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.

    Lalloyer F, Vandewalle B, Percevault F, Torpier G, Kerr-Conte J, Oosterveer M, Paumelle R, Fruchart JC, Kuipers F, Pattou F, Fiévet C, Staels B.

    Diabetes. 2006 Jun;55(6):1605-13.PMID: 16731822 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet.

    Akiyama TE, Lambert G, Nicol CJ, Matsusue K, Peters JM, Brewer HB Jr, Gonzalez FJ.

    J Biol Chem. 2004 May 14;279(20):20874-81. Epub 2004 Mar 4.PMID: 15001574 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency.

    Miles PD, Barak Y, He W, Evans RM, Olefsky JM.

    J Clin Invest. 2000 Feb;105(3):287-92.PMID: 10675354 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Pan-PPAR agonist beneficial effects in overweight mice fed a high-fat high-sucrose diet.

    Fernandes-Santos C, Carneiro RE, de Souza Mendonca L, Aguila MB, Mandarim-de-Lacerda CA.

    Nutrition. 2009 Jul-Aug;25(7-8):818-27. Epub 2009 Mar 5.PMID: 19268533 [PubMed - indexed for MEDLINE]Related articles

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