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    Results: 1 to 20 of 284

    1.

    Transgenic overexpression of hepatocyte growth factor in the beta-cell markedly improves islet function and islet transplant outcomes in mice.

    García-Ocaña A, Vasavada RC, Cebrian A, Reddy V, Takane KK, López-Talavera JC, Stewart AF.

    Diabetes. 2001 Dec;50(12):2752-62.PMID: 11723058 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia.

    Garcia-Ocaña A, Takane KK, Syed MA, Philbrick WM, Vasavada RC, Stewart AF.

    J Biol Chem. 2000 Jan 14;275(2):1226-32.PMID: 10625667 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death.

    Garcia-Ocana A, Takane KK, Reddy VT, Lopez-Talavera JC, Vasavada RC, Stewart AF.

    J Biol Chem. 2003 Jan 3;278(1):343-51. Epub 2002 Oct 25.PMID: 12403787 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Overexpression of parathyroid hormone-related protein inhibits pancreatic beta-cell death in vivo and in vitro.

    Cebrian A, García-Ocaña A, Takane KK, Sipula D, Stewart AF, Vasavada RC.

    Diabetes. 2002 Oct;51(10):3003-13.PMID: 12351440 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Hepatocyte growth factor gene therapy for islet transplantation.

    Rao P, Cozar-Castellano I, Roccisana J, Vasavada RC, Garcia-Ocaña A.

    Expert Opin Biol Ther. 2004 Apr;4(4):507-18. Review.PMID: 15102600 [PubMed - indexed for MEDLINE]Related articles

    6.

    Characterization of mice doubly transgenic for parathyroid hormone-related protein and murine placental lactogen: a novel role for placental lactogen in pancreatic beta-cell survival.

    Fujinaka Y, Sipula D, Garcia-Ocaña A, Vasavada RC.

    Diabetes. 2004 Dec;53(12):3120-30.PMID: 15561942 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Hepatocyte growth factor enhances engraftment and function of nonhuman primate islets.

    Fiaschi-Taesch NM, Berman DM, Sicari BM, Takane KK, Garcia-Ocaña A, Ricordi C, Kenyon NS, Stewart AF.

    Diabetes. 2008 Oct;57(10):2745-54.PMID: 18820214 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Hepatocyte growth factor gene therapy for pancreatic islets in diabetes: reducing the minimal islet transplant mass required in a glucocorticoid-free rat model of allogeneic portal vein islet transplantation.

    Lopez-Talavera JC, Garcia-Ocaña A, Sipula I, Takane KK, Cozar-Castellano I, Stewart AF.

    Endocrinology. 2004 Feb;145(2):467-74. Epub 2003 Oct 9.PMID: 14551233 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Targeted inactivation of hepatocyte growth factor receptor c-met in beta-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of beta-cell mass.

    Roccisana J, Reddy V, Vasavada RC, Gonzalez-Pertusa JA, Magnuson MA, Garcia-Ocaña A.

    Diabetes. 2005 Jul;54(7):2090-102.PMID: 15983210 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Protein kinase C-zeta activation markedly enhances beta-cell proliferation: an essential role in growth factor mediated beta-cell mitogenesis.

    Vasavada RC, Wang L, Fujinaka Y, Takane KK, Rosa TC, Mellado-Gil JM, Friedman PA, Garcia-Ocaña A.

    Diabetes. 2007 Nov;56(11):2732-43. Epub 2007 Aug 8.PMID: 17686945 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes.

    Laybutt DR, Weir GC, Kaneto H, Lebet J, Palmiter RD, Sharma A, Bonner-Weir S.

    Diabetes. 2002 Jun;51(6):1793-804.PMID: 12031967 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia.

    Vasavada RC, Garcia-Ocaña A, Zawalich WS, Sorenson RL, Dann P, Syed M, Ogren L, Talamantes F, Stewart AF.

    J Biol Chem. 2000 May 19;275(20):15399-406.PMID: 10809775 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Progressive pancreatic islet hyperplasia in the islet-targeted, parathyroid hormone-related protein-overexpressing mouse.

    Porter SE, Sorenson RL, Dann P, Garcia-Ocana A, Stewart AF, Vasavada RC.

    Endocrinology. 1998 Sep;139(9):3743-51.PMID: 9724026 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function.

    Gannon M, Ray MK, Van Zee K, Rausa F, Costa RH, Wright CV.

    Development. 2000 Jul;127(13):2883-95.PMID: 10851133 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Evaluation of beta-cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21cip.

    Cozar-Castellano I, Weinstock M, Haught M, Velázquez-Garcia S, Sipula D, Stewart AF.

    Diabetes. 2006 Jan;55(1):70-7.PMID: 16380478 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice.

    Gorogawa S, Fujitani Y, Kaneto H, Hazama Y, Watada H, Miyamoto Y, Takeda K, Akira S, Magnuson MA, Yamasaki Y, Kajimoto Y, Hori M.

    Biochem Biophys Res Commun. 2004 Jul 9;319(4):1159-70.PMID: 15194489 [PubMed - indexed for MEDLINE]Related articles

    17.

    The Tet-On system in transgenic mice: inhibition of the mouse pdx-1 gene activity by antisense RNA expression in pancreatic beta-cells.

    Lottmann H, Vanselow J, Hessabi B, Walther R.

    J Mol Med. 2001 Jun;79(5-6):321-8.PMID: 11485027 [PubMed - indexed for MEDLINE]Related articles

    18.

    Overexpression of insulin-like growth factor-II in transgenic mice is associated with pancreatic islet cell hyperplasia.

    Petrik J, Pell JM, Arany E, McDonald TJ, Dean WL, Reik W, Hill DJ.

    Endocrinology. 1999 May;140(5):2353-63.PMID: 10218989 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.

    Welsh M, Christmansson L, Karlsson T, Sandler S, Welsh N.

    Mol Med. 1999 Mar;5(3):169-80.PMID: 10404514 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia.

    Vasavada RC, Cavaliere C, D'Ercole AJ, Dann P, Burtis WJ, Madlener AL, Zawalich K, Zawalich W, Philbrick W, Stewart AF.

    J Biol Chem. 1996 Jan 12;271(2):1200-8.PMID: 8557651 [PubMed - indexed for MEDLINE]Related articlesFree article

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