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    Results: 1 to 20 of 260

    1.

    gamma-Interferon signaling in pancreatic beta-cells is persistent but can be terminated by overexpression of suppressor of cytokine signaling-1.

    Chong MM, Thomas HE, Kay TW.

    Diabetes. 2001 Dec;50(12):2744-51.PMID: 11723057 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity.

    Karlsen AE, Rønn SG, Lindberg K, Johannesen J, Galsgaard ED, Pociot F, Nielsen JH, Mandrup-Poulsen T, Nerup J, Billestrup N.

    Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12191-6. Epub 2001 Oct 2.PMID: 11593036 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

    Chong MM, Chen Y, Darwiche R, Dudek NL, Irawaty W, Santamaria P, Allison J, Kay TW, Thomas HE.

    J Immunol. 2004 May 1;172(9):5714-21.PMID: 15100317 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Suppressor of cytokine signaling-1 regulates the sensitivity of pancreatic beta cells to tumor necrosis factor.

    Chong MM, Thomas HE, Kay TW.

    J Biol Chem. 2002 Aug 2;277(31):27945-52. Epub 2002 May 24.PMID: 12032139 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Thyrotropin induces SOCS-1 (suppressor of cytokine signaling-1) and SOCS-3 in FRTL-5 thyroid cells.

    Park ES, Kim H, Suh JM, Park SJ, Kwon OY, Kim YK, Ro HK, Cho BY, Chung J, Shong M.

    Mol Endocrinol. 2000 Mar;14(3):440-8.PMID: 10707961 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Suppressor of cytokine signaling 1/JAB and suppressor of cytokine signaling 3/cytokine-inducible SH2 containing protein 3 negatively regulate the signal transducers and activators of transcription signaling pathway in normal human epidermal keratinocytes.

    Yamasaki K, Hanakawa Y, Tokumaru S, Shirakata Y, Sayama K, Hanada T, Yoshimura A, Hashimoto K.

    J Invest Dermatol. 2003 Apr;120(4):571-80.PMID: 12648219 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death.

    Suk K, Kim S, Kim YH, Kim KA, Chang I, Yagita H, Shong M, Lee MS.

    J Immunol. 2001 Apr 1;166(7):4481-9.PMID: 11254704 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses.

    Ding Y, Chen D, Tarcsafalvi A, Su R, Qin L, Bromberg JS.

    J Immunol. 2003 Feb 1;170(3):1383-91.PMID: 12538698 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Impaired IFN-gamma-dependent inflammatory responses in human keratinocytes overexpressing the suppressor of cytokine signaling 1.

    Federici M, Giustizieri ML, Scarponi C, Girolomoni G, Albanesi C.

    J Immunol. 2002 Jul 1;169(1):434-42.PMID: 12077274 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells.

    Baetz A, Frey M, Heeg K, Dalpke AH.

    J Biol Chem. 2004 Dec 24;279(52):54708-15. Epub 2004 Oct 18.PMID: 15491991 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Suppressor of cytokine signaling gene expression in human pancreatic islets: modulation by cytokines.

    Santangelo C, Scipioni A, Marselli L, Marchetti P, Dotta F.

    Eur J Endocrinol. 2005 Mar;152(3):485-9.PMID: 15757867 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.

    Flodström-Tullberg M, Yadav D, Hägerkvist R, Tsai D, Secrest P, Stotland A, Sarvetnick N.

    Diabetes. 2003 Nov;52(11):2696-700.PMID: 14578288 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans.

    Heitmeier MR, Scarim AL, Corbett JA.

    J Biol Chem. 1999 Oct 8;274(41):29266-73.PMID: 10506184 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Thyrotropin-mediated repression of class II trans-activator expression in thyroid cells: involvement of STAT3 and suppressor of cytokine signaling.

    Kim H, Suh JM, Hwang ES, Kim DW, Chung HK, Song JH, Hwang JH, Park KC, Ro HK, Jo EK, Chang JS, Lee TH, Lee MS, Kohn LD, Shong M.

    J Immunol. 2003 Jul 15;171(2):616-27.PMID: 12847226 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Triggering of Toll-like receptors modulates IFN-gamma signaling: involvement of serine 727 STAT1 phosphorylation and suppressors of cytokine signaling.

    Dalpke AH, Eckerle S, Frey M, Heeg K.

    Eur J Immunol. 2003 Jul;33(7):1776-87.PMID: 12811837 [PubMed - indexed for MEDLINE]Related articles

    16.

    Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.

    Radaeva S, Jaruga B, Kim WH, Heller T, Liang TJ, Gao B.

    Biochem J. 2004 Apr 1;379(Pt 1):199-208.PMID: 14690454 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS.

    Hong F, Jaruga B, Kim WH, Radaeva S, El-Assal ON, Tian Z, Nguyen VA, Gao B.

    J Clin Invest. 2002 Nov;110(10):1503-13.PMID: 12438448 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Loss of interferon-induced Stat1 phosphorylation in activated T cells.

    Van De Wiele CJ, Marino JH, Whetsell ME, Vo SS, Masengale RM, Teague TK.

    J Interferon Cytokine Res. 2004 Mar;24(3):169-78.PMID: 15035850 [PubMed - indexed for MEDLINE]Related articles

    19.

    Inhibition of IFN-gamma-induced class II transactivator expression by a 19-kDa lipoprotein from Mycobacterium tuberculosis: a potential mechanism for immune evasion.

    Pai RK, Convery M, Hamilton TA, Boom WH, Harding CV.

    J Immunol. 2003 Jul 1;171(1):175-84.PMID: 12816996 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma.

    Cottet S, Dupraz P, Hamburger F, Dolci W, Jaquet M, Thorens B.

    J Biol Chem. 2001 Jul 13;276(28):25862-70. Epub 2001 May 7.PMID: 11342558 [PubMed - indexed for MEDLINE]Related articlesFree article

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