PubMed

Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.

Laviola L, Belsanti G, Davalli AM, Napoli R, Perrini S, Weir GC, Giorgino R, Giorgino F.

Diabetes. 2001 Dec;50(12):2709-20.PMID: 11723053 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet transplantation restores normal levels of insulin receptor and substrate tyrosine phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle and myocardium of streptozocin-induced diabetic rats.

Giorgino F, Logoluso F, Davalli AM, Napoli R, Laviola L, Hirshman MF, Horton ES, Weir GC, Smith RJ.

Diabetes. 1999 Apr;48(4):801-12.PMID: 10102697 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of streptozocin-induced diabetes and islet cell transplantation on insulin signaling in rat skeletal muscle.

Markuns JF, Napoli R, Hirshman MF, Davalli AM, Cheatham B, Goodyear LJ.

Endocrinology. 1999 Jan;140(1):106-11.PMID: 9886813 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.

Ogihara T, Asano T, Ando K, Chiba Y, Sekine N, Sakoda H, Anai M, Onishi Y, Fujishiro M, Ono H, Shojima N, Inukai K, Fukushima Y, Kikuchi M, Fujita T.

Diabetes. 2001 Mar;50(3):573-83.PMID: 11246877 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.

Andreozzi F, Laratta E, Sciacqua A, Perticone F, Sesti G.

Circ Res. 2004 May 14;94(9):1211-8. Epub 2004 Mar 25.PMID: 15044323 [PubMed - indexed for MEDLINE]Related articlesFree article

Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism.

Miele C, Riboulet A, Maitan MA, Oriente F, Romano C, Formisano P, Giudicelli J, Beguinot F, Van Obberghen E.

J Biol Chem. 2003 Nov 28;278(48):47376-87. Epub 2003 Sep 11.PMID: 12970360 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.

Conejo R, Lorenzo M.

J Cell Physiol. 2001 Apr;187(1):96-108.PMID: 11241354 [PubMed - indexed for MEDLINE]Related articles

Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors.

Inoue G, Cheatham B, Kahn CR.

J Biol Chem. 1996 Nov 8;271(45):28206-11.PMID: 8910437 [PubMed - indexed for MEDLINE]Related articlesFree article

Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis.

Sasaoka T, Ishiki M, Wada T, Hori H, Hirai H, Haruta T, Ishihara H, Kobayashi M.

Endocrinology. 2001 Dec;142(12):5226-35.PMID: 11713219 [PubMed - indexed for MEDLINE]Related articlesFree article

Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control.

Parpal S, Karlsson M, Thorn H, Strålfors P.

J Biol Chem. 2001 Mar 30;276(13):9670-8. Epub 2000 Dec 19.PMID: 11121405 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway.

Kurihara S, Hakuno F, Takahashi S.

Endocr J. 2000 Dec;47(6):739-51.PMID: 11228049 [PubMed - indexed for MEDLINE]Related articles

Insulin receptor substrate-1 enhances growth hormone-induced proliferation.

Liang L, Zhou T, Jiang J, Pierce JH, Gustafson TA, Frank SJ.

Endocrinology. 1999 May;140(5):1972-83.PMID: 10218944 [PubMed - indexed for MEDLINE]Related articlesFree article

The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance.

Carvalheira JB, Calegari VC, Zecchin HG, Nadruz W Jr, Guimarães RB, Ribeiro EB, Franchini KG, Velloso LA, Saad MJ.

Endocrinology. 2003 Dec;144(12):5604-14. Epub 2003 Sep 4.PMID: 12960006 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of IRS-2 tyrosine phosphorylation in fasting and diabetes.

Rojas FA, Hirata AE, Saad MJ.

Mol Cell Endocrinol. 2001 Oct 25;183(1-2):63-9.PMID: 11604226 [PubMed - indexed for MEDLINE]Related articles

Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.

Welsh N, Makeeva N, Welsh M.

Mol Med. 2002 Nov;8(11):695-704.PMID: 12520086 [PubMed - indexed for MEDLINE]Related articlesFree article

GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.

Annerén C, Welsh M.

Mol Med. 2002 Nov;8(11):705-13.PMID: 12520087 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective interaction between leptin and insulin signaling pathways in a hepatic cell line.

Szanto I, Kahn CR.

Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2355-60.PMID: 10688912 [PubMed - indexed for MEDLINE]Related articlesFree article

Morphine induces desensitization of insulin receptor signaling.

Li Y, Eitan S, Wu J, Evans CJ, Kieffer B, Sun X, Polakiewicz RD.

Mol Cell Biol. 2003 Sep;23(17):6255-66.PMID: 12917346 [PubMed - indexed for MEDLINE]Related articlesFree article

Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells.

Hennige AM, Lammers R, Arlt D, Höppner W, Strack V, Niederfellner G, Seif FJ, Häring HU, Kellerer M.

Mol Cell Endocrinol. 2000 Sep 25;167(1-2):69-76.PMID: 11000521 [PubMed - indexed for MEDLINE]Related articles

Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.

Andreozzi F, D'Alessandris C, Federici M, Laratta E, Del Guerra S, Del Prato S, Marchetti P, Lauro R, Perticone F, Sesti G.

Endocrinology. 2004 Jun;145(6):2845-57. Epub 2004 Mar 4.PMID: 15001544 [PubMed - indexed for MEDLINE]Related articlesFree article