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    Results: 1 to 20 of 275

    1.

    Protection from type 1 diabetes in the face of high levels of activated autoaggressive lymphocytes in a viral transgenic mouse model crossed to the SV129 strain.

    von Herrath MG, Wolfe T, Möhrle U, Coon B, Hughes A.

    Diabetes. 2001 Dec;50(12):2700-8.PMID: 11723052 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes.

    Holz A, Dyrberg T, Hagopian W, Homann D, von Herrath M, Oldstone MB.

    J Immunol. 2000 Nov 15;165(10):5945-53.PMID: 11067957 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Pathological changes in the islet milieu precede infiltration of islets and destruction of beta-cells by autoreactive lymphocytes in a transgenic model of virus-induced IDDM.

    von Herrath M, Holz A.

    J Autoimmun. 1997 Jun;10(3):231-8.PMID: 9218748 [PubMed - indexed for MEDLINE]Related articles

    4.

    Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse-derived beta-cell cytotoxic CD8+ T-cell clones in vivo.

    Utsugi T, Yoon JW, Park BJ, Imamura M, Averill N, Kawazu S, Santamaria P.

    Diabetes. 1996 Aug;45(8):1121-31.PMID: 8690161 [PubMed - indexed for MEDLINE]Related articles

    5.

    In vivo treatment with a MHC class I-restricted blocking peptide can prevent virus-induced autoimmune diabetes.

    von Herrath MG, Coon B, Lewicki H, Mazarguil H, Gairin JE, Oldstone MB.

    J Immunol. 1998 Nov 1;161(9):5087-96.PMID: 9794447 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence.

    Holz A, Bot A, Coon B, Wolfe T, Grusby MJ, von Herrath MG.

    J Immunol. 1999 Nov 15;163(10):5374-82.PMID: 10553062 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Nonmitogenic CD3 antibody reverses virally induced (rat insulin promoter-lymphocytic choriomeningitis virus) autoimmune diabetes without impeding viral clearance.

    von Herrath MG, Coon B, Wolfe T, Chatenoud L.

    J Immunol. 2002 Jan 15;168(2):933-41.PMID: 11777992 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Enhanced T cell responses contribute to the genetic predisposition of CD8-mediated spontaneous autoimmunity.

    Garza KM, McKall-Faienza KJ, Otheki T, Zakarian A, Odermatt B, Ohashi PS.

    Eur J Immunol. 2002 Mar;32(3):885-94.PMID: 11870633 [PubMed - indexed for MEDLINE]Related articles

    9.

    Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus.

    von Herrath MG, Oldstone MB.

    J Exp Med. 1997 Feb 3;185(3):531-9.PMID: 9053453 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity.

    Kägi D, Odermatt B, Ohashi PS, Zinkernagel RM, Hengartner H.

    J Exp Med. 1996 May 1;183(5):2143-52.PMID: 8642324 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Focal expression of interleukin-2 does not break unresponsiveness to "self" (viral) antigen expressed in beta cells but enhances development of autoimmune disease (diabetes) after initiation of an anti-self immune response.

    von Herrath MG, Allison J, Miller JF, Oldstone MB.

    J Clin Invest. 1995 Feb;95(2):477-85.PMID: 7860729 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    [Viral antigen induced autoimmunity: an animal model for diabetes mellitus type I]

    Hengartner H.

    Verh Dtsch Ges Pathol. 1994;78:177-9. German. PMID: 7533982 [PubMed - indexed for MEDLINE]Related articles

    13.

    The role of lymphocyte subsets in accelerated diabetes in nonobese diabetic-rat insulin promoter-B7-1 (NOD-RIP-B7-1) mice.

    Wong FS, Visintin I, Wen L, Granata J, Flavell R, Janeway CA.

    J Exp Med. 1998 Jun 15;187(12):1985-93.PMID: 9625758 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes.

    Barral AM, Thomas HE, Ling EM, Darwiche R, Rodrigo E, Christen U, Ejrnaes M, Wolfe T, Kay TW, von Herrath MG.

    J Autoimmun. 2006 Nov;27(3):166-73. Epub 2006 Oct 10.PMID: 17045460 [PubMed - indexed for MEDLINE]Related articles

    15.

    Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue.

    Ludewig B, Odermatt B, Landmann S, Hengartner H, Zinkernagel RM.

    J Exp Med. 1998 Oct 19;188(8):1493-501.PMID: 9782126 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Pathogenesis and treatment of virus-induced autoimmune diabetes: novel insights gained from the RIP-LCMV transgenic mouse model.

    von Herrath MG, Homann D, Gairin JE, Oldstone MB.

    Biochem Soc Trans. 1997 May;25(2):630-5. Review. No abstract available. PMID: 9191170 [PubMed - indexed for MEDLINE]Related articles

    17.

    Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.

    Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S.

    Diabetes. 2001 Sep;50(9):1992-2000.PMID: 11522664 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens.

    Yamanouchi J, Verdaguer J, Han B, Amrani A, Serra P, Santamaria P.

    J Immunol. 2003 Dec 15;171(12):6900-9.PMID: 14662897 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha.

    Ohashi PS, Oehen S, Aichele P, Pircher H, Odermatt B, Herrera P, Higuchi Y, Buerki K, Hengartner H, Zinkernagel RM.

    J Immunol. 1993 Jun 1;150(11):5185-94.PMID: 8496610 [PubMed - indexed for MEDLINE]Related articles

    20.

    Virus specificity of cytotoxic T lymphocytes generated during acute lymphocytic choriomeningitis virus infection: role of the H-2 region in determining cross-reactivity for different lymphocytic choriomeningitis virus strains.

    Ahmed R, Byrne JA, Oldstone MB.

    J Virol. 1984 Jul;51(1):34-41.PMID: 6610062 [PubMed - indexed for MEDLINE]Related articlesFree article

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