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Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?

Fry MJ.

Breast Cancer Res. 2001;3(5):304-12. Epub 2001 Jun 28. Review.PMID: 11597319 [PubMed - indexed for MEDLINE]Related articlesFree article

3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.

Maurer M, Su T, Saal LH, Koujak S, Hopkins BD, Barkley CR, Wu J, Nandula S, Dutta B, Xie Y, Chin YR, Kim DI, Ferris JS, Gruvberger-Saal SK, Laakso M, Wang X, Memeo L, Rojtman A, Matos T, Yu JS, Cordon-Cardo C, Isola J, Terry MB, Toker A, Mills GB, Zhao JJ, Murty VV, Hibshoosh H, Parsons R.

Cancer Res. 2009 Aug 1;69(15):6299-306. Epub 2009 Jul 14.PMID: 19602588 [PubMed - indexed for MEDLINE]Related articles

Phosphoinositide 3-kinase targeting by the beta galactoside binding protein cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death.

Wells V, Mallucci L.

Breast Cancer Res. 2009;11(1):R2. Epub 2009 Jan 8.PMID: 19133120 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitogenic signalling by B2 bradykinin receptor in epithelial breast cells.

Greco S, Muscella A, Elia MG, Romano S, Storelli C, Marsigliante S.

J Cell Physiol. 2004 Oct;201(1):84-96.PMID: 15281091 [PubMed - indexed for MEDLINE]Related articles

Critical role for lipid raft-associated Src kinases in activation of PI3K-Akt signalling.

Arcaro A, Aubert M, Espinosa del Hierro ME, Khanzada UK, Angelidou S, Tetley TD, Bittermann AG, Frame MC, Seckl MJ.

Cell Signal. 2007 May;19(5):1081-92. Epub 2006 Dec 29.PMID: 17275257 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylinositol 4-kinases.

Gehrmann T, Heilmeyer LM Jr.

Eur J Biochem. 1998 Apr 15;253(2):357-70. Review.PMID: 9654085 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.

Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.

Int J Oncol. 2004 Mar;24(3):591-608.PMID: 14767544 [PubMed - indexed for MEDLINE]Related articles

Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation.

Pozo-Guisado E, Lorenzo-Benayas MJ, Fernández-Salguero PM.

Int J Cancer. 2004 Mar 20;109(2):167-73.PMID: 14750165 [PubMed - indexed for MEDLINE]Related articles

Expression of HER-2 in MCF-7 breast cancer cells modulates anti-apoptotic proteins Survivin and Bcl-2 via the extracellular signal-related kinase (ERK) and phosphoinositide-3 kinase (PI3K) signalling pathways.

Siddiqa A, Long LM, Li L, Marciniak RA, Kazhdan I.

BMC Cancer. 2008 May 2;8:129.PMID: 18454859 [PubMed - indexed for MEDLINE]Related articlesFree article

IgA Fc receptor (FcalphaR) cross-linking recruits tyrosine kinases, phosphoinositide kinases and serine/threonine kinases to glycolipid rafts.

Lang ML, Chen YW, Shen L, Gao H, Lang GA, Wade TK, Wade WF.

Biochem J. 2002 Jun 1;364(Pt 2):517-25.PMID: 12023895 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatidylinositol 3-kinase/AKT signalling pathway components in human breast cancer: clinicopathological correlations.

Gershtein ES, Scherbakov AM, Shatskaya VA, Kushlinsky NE, Krasil'nikov MA.

Anticancer Res. 2007 Jul-Aug;27(4A):1777-82.PMID: 17649772 [PubMed - indexed for MEDLINE]Related articles

Phosphoinositide 3-kinase and its targets in B-cell and T-cell signaling.

Fruman DA.

Curr Opin Immunol. 2004 Jun;16(3):314-20. Review.PMID: 15134780 [PubMed - indexed for MEDLINE]Related articles

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

Katso R, Okkenhaug K, Ahmadi K, White S, Timms J, Waterfield MD.

Annu Rev Cell Dev Biol. 2001;17:615-75. Review.PMID: 11687500 [PubMed - indexed for MEDLINE]Related articles

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.

Lu Y, Yu Q, Liu JH, Zhang J, Wang H, Koul D, McMurray JS, Fang X, Yung WK, Siminovitch KA, Mills GB.

J Biol Chem. 2003 Oct 10;278(41):40057-66. Epub 2003 Jul 17.PMID: 12869565 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M.

Adv Enzyme Regul. 2006;46:249-79. Epub 2006 Jul 18.PMID: 16854453 [PubMed - indexed for MEDLINE]Related articles

Extracellular matrix enhances heregulin-dependent BRCA1 phosphorylation and suppresses BRCA1 expression through its C terminus.

Miralem T, Avraham HK.

Mol Cell Biol. 2003 Jan;23(2):579-93.PMID: 12509456 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis.

Cox SS, van der Giezen M, Tarr SJ, Crompton MR, Tovar J.

BMC Microbiol. 2006 May 18;6:45.PMID: 16707026 [PubMed - indexed for MEDLINE]Related articlesFree article

Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action.

Yakes FM, Chinratanalab W, Ritter CA, King W, Seelig S, Arteaga CL.

Cancer Res. 2002 Jul 15;62(14):4132-41.PMID: 12124352 [PubMed - indexed for MEDLINE]Related articlesFree article

Collagen I induction by high glucose levels is mediated by epidermal growth factor receptor and phosphoinositide 3-kinase/Akt signalling in mesangial cells.

Wu D, Peng F, Zhang B, Ingram AJ, Gao B, Krepinsky JC.

Diabetologia. 2007 Sep;50(9):2008-18. Epub 2007 Jul 11.PMID: 17622510 [PubMed - indexed for MEDLINE]Related articles

TrkA overexpression enhances growth and metastasis of breast cancer cells.

Lagadec C, Meignan S, Adriaenssens E, Foveau B, Vanhecke E, Romon R, Toillon RA, Oxombre B, Hondermarck H, Le Bourhis X.

Oncogene. 2009 May 7;28(18):1960-70. Epub 2009 Mar 30.PMID: 19330021 [PubMed - indexed for MEDLINE]Related articles