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    Results: 1 to 20 of 139

    1.

    Analysis of the coding and promoter regions of the autoantigen IA-2 in subjects with and without autoantibodies to IA-2.

    Cai T, Xie J, She JX, Notkins AL.

    Diabetes. 2001 Oct;50(10):2406-9.PMID: 11574427 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Genomic structure and promoter sequence of the insulin-dependent diabetes mellitus autoantigen, IA-2 (PTPRN).

    Xie J, Zhang B, Lan MS, Notkins AL.

    Genomics. 1998 Dec 1;54(2):338-43.PMID: 9828138 [PubMed - indexed for MEDLINE]Related articles

    3.

    Human monoclonal antibodies isolated from type I diabetes patients define multiple epitopes in the protein tyrosine phosphatase-like IA-2 antigen.

    Kolm-Litty V, Berlo S, Bonifacio E, Bearzatto M, Engel AM, Christie M, Ziegler AG, Wild T, Endl J.

    J Immunol. 2000 Oct 15;165(8):4676-84.PMID: 11035111 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Mapping of novel autoreactive epitopes of the diabetes-associated autoantigen IA-2.

    Seissler J, Schott M, Morgenthaler NG, Scherbaum WA.

    Clin Exp Immunol. 2000 Nov;122(2):157-63.PMID: 11091269 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents.

    Honeyman MC, Stone NL, Harrison LC.

    Mol Med. 1998 Apr;4(4):231-9.PMID: 9606176 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Autoantibodies in insulin-dependent diabetes recognize distinct cytoplasmic domains of the protein tyrosine phosphatase-like IA-2 autoantigen.

    Lampasona V, Bearzatto M, Genovese S, Bosi E, Ferrari M, Bonifacio E.

    J Immunol. 1996 Sep 15;157(6):2707-11.PMID: 8805677 [PubMed - indexed for MEDLINE]Related articles

    7.

    Polymorphism in gene for islet autoantigen, IA-2, and type 1 diabetes in Japanese subjects.

    Nishino M, Ikegami H, Kawaguchi Y, Fujisawa T, Kawabata Y, Shintani M, Ono M, Horiki M, Kawasaki E, Ogihara T.

    Hum Immunol. 2001 May;62(5):518-22.PMID: 11334676 [PubMed - indexed for MEDLINE]Related articles

    8.

    IDA-1, a Caenorhabditis elegans homolog of the diabetic autoantigens IA-2 and phogrin, is expressed in peptidergic neurons in the worm.

    Zahn TR, Macmorris MA, Dong W, Day R, Hutton JC.

    J Comp Neurol. 2001 Jan 1;429(1):127-43.PMID: 11086294 [PubMed - indexed for MEDLINE]Related articles

    9.

    Differential splicing of the IA-2 mRNA in pancreas and lymphoid organs as a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen.

    Diez J, Park Y, Zeller M, Brown D, Garza D, Ricordi C, Hutton J, Eisenbarth GS, Pugliese A.

    Diabetes. 2001 Apr;50(4):895-900.PMID: 11289059 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens.

    Bearzatto M, Naserke H, Piquer S, Koczwara K, Lampasona V, Williams A, Christie MR, Bingley PJ, Ziegler AG, Bonifacio E.

    J Immunol. 2002 Apr 15;168(8):4202-8.PMID: 11937581 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Genomic structure of mouse IA-2: comparison with its human homologue.

    Saeki K, Xie J, Notkins AL.

    Diabetologia. 2000 Nov;43(11):1429-34.PMID: 11126414 [PubMed - indexed for MEDLINE]Related articles

    12.

    Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment.

    Lu J, Li Q, Xie H, Chen ZJ, Borovitskaya AE, Maclaren NK, Notkins AL, Lan MS.

    Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2307-11.PMID: 8637868 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Autoantigens in insulin-dependent diabetes mellitus: molecular cloning and characterization of human IA-2 beta.

    Li Q, Borovitskaya AE, DeSilva MG, Wasserfall C, Maclaren NK, Notkins AL, Lan MS.

    Proc Assoc Am Physicians. 1997 Jul;109(4):429-39.PMID: 9220540 [PubMed - indexed for MEDLINE]Related articles

    14.

    Engineering and expression of the intracellular domain of insulinoma-associated tyrosine phosphatase (IA-2ic), a type 1 diabetes autoantigen, in plants.

    Mett V, Shamloul AM, Hirai H, Zhou Z, Notkins A, Yusibov V.

    Transgenic Res. 2007 Feb;16(1):77-84. Epub 2006 Nov 11.PMID: 17103024 [PubMed - indexed for MEDLINE]Related articles

    15.

    Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes.

    Cui L, Yu WP, DeAizpurua HJ, Schmidli RS, Pallen CJ.

    J Biol Chem. 1996 Oct 4;271(40):24817-23.PMID: 8798755 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Proliferative responses to selected peptides of IA-2 in identical twins discordant for Type 1 diabetes.

    Schulz RM, Hawa M, Leslie RD, Sinigaglia F, Passini N, Rogge L, Picard JK, Londei M.

    Diabetes Metab Res Rev. 2000 May-Jun;16(3):150-6.PMID: 10867713 [PubMed - indexed for MEDLINE]Related articles

    17.

    Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice.

    Kubosaki A, Gross S, Miura J, Saeki K, Zhu M, Nakamura S, Hendriks W, Notkins AL.

    Diabetes. 2004 Jul;53(7):1684-91.PMID: 15220191 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    T-cell lines reactive to an immunodominant epitope of the tyrosine phosphatase-like autoantigen IA-2 in type 1 diabetes.

    Hawkes CJ, Schloot NC, Marks J, Willemen SJ, Drijfhout JW, Mayer EK, Christie MR, Roep BO.

    Diabetes. 2000 Mar;49(3):356-66.PMID: 10868956 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Novel fusion proteins in the analysis of diabetes-associated autoantibodies to GAD65 and IA-2.

    Zavialov A, Ankelo M, Westerlund-Karlsson A, Knip M, Ilonen J, Hinkkanen A.

    J Immunol Methods. 2000 Dec 1;246(1-2):91-6.PMID: 11121550 [PubMed - indexed for MEDLINE]Related articles

    20.

    Application of phage display peptide library to autoimmune diabetes: identification of IA-2/ICA512bdc dominant autoantigenic epitopes.

    Farilla L, Tiberti C, Luzzago A, Yu L, Eisenbarth GS, Cortese R, Dotta F, Di Mario U.

    Eur J Immunol. 2002 May;32(5):1420-7.PMID: 11981830 [PubMed - indexed for MEDLINE]Related articles

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