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    Results: 1 to 20 of 133

    1.

    Effects of leptin deficiency and short-term repletion on hepatic gene expression in genetically obese mice.

    Ferrante AW Jr, Thearle M, Liao T, Leibel RL.

    Diabetes. 2001 Oct;50(10):2268-78.PMID: 11574408 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Transcriptional profiling reveals global defects in energy metabolism, lipoprotein, and bile acid synthesis and transport with reversal by leptin treatment in ob/ob mouse liver.

    Liang CP, Tall AR.

    J Biol Chem. 2001 Dec 28;276(52):49066-76. Epub 2001 Sep 10.PMID: 11551957 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

    Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C.

    Diabetes. 2006 Aug;55(8):2159-70.PMID: 16873678 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Partial leptin deficiency favors diet-induced obesity and related metabolic disorders in mice.

    Begriche K, Lettéron P, Abbey-Toby A, Vadrot N, Robin MA, Bado A, Pessayre D, Fromenty B.

    Am J Physiol Endocrinol Metab. 2008 May;294(5):E939-51. Epub 2008 Mar 18.PMID: 18349116 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice.

    Iwaniec UT, Boghossian S, Lapke PD, Turner RT, Kalra SP.

    Peptides. 2007 May;28(5):1012-9. Epub 2007 Feb 12.PMID: 17346852 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Leptin regulates gallbladder genes related to absorption and secretion.

    Swartz-Basile DA, Lu D, Basile DP, Graewin SJ, Al-Azzawi H, Kiely JM, Mathur A, Yancey K, Pitt HA.

    Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G84-90. Epub 2007 Apr 26.PMID: 17463181 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Evaluation of liver fatty acid oxidation in the leptin-deficient obese mouse.

    Brix AE, Elgavish A, Nagy TR, Gower BA, Rhead WJ, Wood PA.

    Mol Genet Metab. 2002 Mar;75(3):219-26.PMID: 11914033 [PubMed - indexed for MEDLINE]Related articles

    8.

    Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice.

    Liu Y, Nakagawa Y, Wang Y, Li R, Li X, Ohzeki T, Friedman TC.

    Diabetes. 2003 Jun;52(6):1409-16.PMID: 12765951 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice.

    Iizuka K, Miller B, Uyeda K.

    Am J Physiol Endocrinol Metab. 2006 Aug;291(2):E358-64. Epub 2006 May 16.PMID: 16705063 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Stearoyl-CoA desaturase-1 and the metabolic syndrome.

    Cohen P, Ntambi JM, Friedman JM.

    Curr Drug Targets Immune Endocr Metabol Disord. 2003 Dec;3(4):271-80. Review.PMID: 14683458 [PubMed - indexed for MEDLINE]Related articles

    11.

    Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin.

    Leclercq IA, Vansteenberghe M, Lebrun VB, VanHul NK, Abarca-Quinones J, Sempoux CL, Picard C, Stärkel P, Horsmans YL.

    Lab Invest. 2006 Nov;86(11):1161-71. Epub 2006 Sep 18.PMID: 16983330 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.

    Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N.

    J Biol Chem. 2002 May 31;277(22):19353-7. Epub 2002 Mar 28.PMID: 11923308 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Heterozygosity for Lep(ob) or Lep(rdb) affects body composition and leptin homeostasis in adult mice.

    Chung WK, Belfi K, Chua M, Wiley J, Mackintosh R, Nicolson M, Boozer CN, Leibel RL.

    Am J Physiol. 1998 Apr;274(4 Pt 2):R985-90.PMID: 9575960 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48-/-Lepob/ob mice devoid of ApoE or Ldlr.

    Lloyd DJ, McCormick J, Helmering J, Kim KW, Wang M, Fordstrom P, Kaufman SA, Lindberg RA, Véniant MM.

    Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E496-505. Epub 2007 Dec 26.PMID: 18160459 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Reduction of obesity, as induced by leptin, reverses endothelial dysfunction in obese (Lep(ob)) mice.

    Winters B, Mo Z, Brooks-Asplund E, Kim S, Shoukas A, Li D, Nyhan D, Berkowitz DE.

    J Appl Physiol. 2000 Dec;89(6):2382-90.PMID: 11090593 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.

    Segal-Lieberman G, Bradley RL, Kokkotou E, Carlson M, Trombly DJ, Wang X, Bates S, Myers MG Jr, Flier JS, Maratos-Flier E.

    Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10085-90. Epub 2003 Aug 1.PMID: 12897241 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Leptin induces the hepatic high density lipoprotein receptor scavenger receptor B type I (SR-BI) but not cholesterol 7alpha-hydroxylase (Cyp7a1) in leptin-deficient (ob/ob) mice.

    Lundåsen T, Liao W, Angelin B, Rudling M.

    J Biol Chem. 2003 Oct 31;278(44):43224-8. Epub 2003 Aug 13.PMID: 12917427 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and food intake.

    Trevaskis JL, Butler AA.

    Endocrinology. 2005 Oct;146(10):4257-65. Epub 2005 Jun 30. Erratum in: Endocrinology. 2005 Dec;146(12):5387. PMID: 15994342 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Regulation of metabolic responses by adipocyte/macrophage Fatty Acid-binding proteins in leptin-deficient mice.

    Cao H, Maeda K, Gorgun CZ, Kim HJ, Park SY, Shulman GI, Kim JK, Hotamisligil GS.

    Diabetes. 2006 Jul;55(7):1915-22.PMID: 16804058 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    A novel aminosterol reverses diabetes and fatty liver disease in obese mice.

    Takahashi N, Qi Y, Patel HR, Ahima RS.

    J Hepatol. 2004 Sep;41(3):391-8.PMID: 15336441 [PubMed - indexed for MEDLINE]Related articles

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