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    Results: 1 to 20 of 136

    1.

    Inducible and reversible beta-cell autoimmunity and hyperplasia in transgenic mice expressing a conditional oncogene.

    Berkovich I, Efrat S.

    Diabetes. 2001 Oct;50(10):2260-7.PMID: 11574407 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene.

    Efrat S, Fusco-DeMane D, Lemberg H, al Emran O, Wang X.

    Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3576-80.PMID: 7724601 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Oncogenic co-operation in beta-cell tumorigenesis.

    Pelengaris S, Khan M.

    Endocr Relat Cancer. 2001 Dec;8(4):307-14. Review.PMID: 11733227 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Tumor microenvironment can restrict the effectiveness of activated antitumor lymphocytes.

    Ganss R, Hanahan D.

    Cancer Res. 1998 Oct 15;58(20):4673-81.PMID: 9788621 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Correction of hyperglycemia in diabetic mice transplanted with reversibly immortalized pancreatic beta cells controlled by the tet-on regulatory system.

    Milo-Landesman D, Surana M, Berkovich I, Compagni A, Christofori G, Fleischer N, Efrat S.

    Cell Transplant. 2001;10(7):645-50.PMID: 11714200 [PubMed - indexed for MEDLINE]Related articles

    6.

    Breaking immunologic ignorance to an antigenic peptide of simian virus 40 large T antigen.

    Soldevila G, Geiger T, Flavell RA.

    J Immunol. 1995 Dec 15;155(12):5590-600.PMID: 7499842 [PubMed - indexed for MEDLINE]Related articles

    7.

    Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes.

    Laybutt DR, Weir GC, Kaneto H, Lebet J, Palmiter RD, Sharma A, Bonner-Weir S.

    Diabetes. 2002 Jun;51(6):1793-804.PMID: 12031967 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Hyperplasia and tumors of the islets of Langerhans in mice bearing an elastase I-SV40 T-antigen fusion gene.

    Bell RH Jr, Memoli VA, Longnecker DS.

    Carcinogenesis. 1990 Aug;11(8):1393-8.PMID: 2167183 [PubMed - indexed for MEDLINE]Related articles

    9.

    T cells are responsive to the simian virus 40 large tumor antigen transgenically expressed in pancreatic islets.

    Geiger T, Soldevila G, Flavell RA.

    J Immunol. 1993 Dec 15;151(12):7030-7.PMID: 8258707 [PubMed - indexed for MEDLINE]Related articles

    10.

    Functional analysis of a conditionally transformed pancreatic beta-cell line.

    Fleischer N, Chen C, Surana M, Leiser M, Rossetti L, Pralong W, Efrat S.

    Diabetes. 1998 Sep;47(9):1419-25.PMID: 9726230 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Apoptosis of autoreactive CD8 lymphocytes as a potential mechanism for the abrogation of type 1 diabetes by islet-specific TNF-alpha expression at a time when the autoimmune process is already ongoing.

    Christen U, Von Herrath MG.

    Ann N Y Acad Sci. 2002 Apr;958:166-9.PMID: 12021099 [PubMed - indexed for MEDLINE]Related articles

    12.

    Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen.

    Ewald D, Li M, Efrat S, Auer G, Wall RJ, Furth PA, Hennighausen L.

    Science. 1996 Sep 6;273(5280):1384-6.PMID: 8703072 [PubMed - indexed for MEDLINE]Related articles

    13.

    Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice.

    Onrust SV, Hartl PM, Rosen SD, Hanahan D.

    J Clin Invest. 1996 Jan 1;97(1):54-64.PMID: 8550850 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Transgene expression and repression in transgenic rats bearing the phosphoenolpyruvate carboxykinase-simian virus 40 T antigen or the phosphoenolpyruvate carboxykinase-transforming growth factor-alpha constructs.

    Haas MJ, Dragan YP, Hikita H, Shimel R, Takimoto K, Heath S, Vaughan J, Pitot HC.

    Am J Pathol. 1999 Jul;155(1):183-92.PMID: 10393850 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.

    Eldor R, Yeffet A, Baum K, Doviner V, Amar D, Ben-Neriah Y, Christofori G, Peled A, Carel JC, Boitard C, Klein T, Serup P, Eizirik DL, Melloul D.

    Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5072-7. Epub 2006 Mar 21.PMID: 16551748 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Insulitis and islet-cell antibody formation in rats with experimentally reduced beta-cell mass.

    Lampeter EF, Tubes M, Klemens C, Brocker U, Friemann J, Kolb-Bachofen V, Gries FA, Kolb H.

    Diabetologia. 1995 Dec;38(12):1397-404.PMID: 8786012 [PubMed - indexed for MEDLINE]Related articles

    17.

    Vaccine therapy of established tumors in the absence of autoimmunity.

    Hodge JW, Grosenbach DW, Aarts WM, Poole DJ, Schlom J.

    Clin Cancer Res. 2003 May;9(5):1837-49.PMID: 12738742 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Expression and immune recognition of SV40 Tag in transgenic mice that develop metastatic osteosarcomas.

    Marton I, Johnson SE, Damjanov I, Currier KS, Sundberg JP, Knowles BB.

    Transgenic Res. 2000 Apr;9(2):115-25.PMID: 10951695 [PubMed - indexed for MEDLINE]Related articles

    19.

    Conditional expression of SV40 T-antigen in mouse cardiomyocytes facilitates an inducible switch from proliferation to differentiation.

    Rybkin II, Markham DW, Yan Z, Bassel-Duby R, Williams RS, Olson EN.

    J Biol Chem. 2003 May 2;278(18):15927-34. Epub 2003 Feb 17.PMID: 12590133 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Virally induced inflammation triggers fratricide of Fas-ligand-expressing beta-cells.

    Christen U, Darwiche R, Thomas HE, Wolfe T, Rodrigo E, Chervonsky A, Flavell RA, von Herrath MG.

    Diabetes. 2004 Mar;53(3):591-6.PMID: 14988242 [PubMed - indexed for MEDLINE]Related articlesFree article

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