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    Results: 1 to 20 of 139

    1.

    Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome.

    El Mkadem SA, Lautier C, Macari F, Molinari N, Lefèbvre P, Renard E, Gris JC, Cros G, Daurès JP, Bringer J, White MF, Grigorescu F.

    Diabetes. 2001 Sep;50(9):2164-8.PMID: 11522686 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Polymorphisms in the insulin receptor substrate-1 (IRS-1) gene and the insulin receptor substrate-2 (IRS-2) gene influence glucose homeostasis and body mass index in women with polycystic ovary syndrome and non-hyperandrogenic controls.

    Villuendas G, Botella-Carretero JI, Roldán B, Sancho J, Escobar-Morreale HF, San Millán JL.

    Hum Reprod. 2005 Nov;20(11):3184-91. Epub 2005 Jul 21.PMID: 16037106 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.

    Lin TC, Yen JM, Gong KB, Kuo TC, Ku DC, Liang SF, Wu MJ.

    BMC Med Genet. 2006 Apr 7;7:36.PMID: 16603055 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Insulin secretion in women who have polycystic ovary syndrome and carry the Gly972Arg variant of insulin receptor substrate-1 in response to a high-glycemic or low-glycemic carbohydrate load.

    Sir-Petermann T, Angel B, Maliqueo M, Santos JL, Riesco MV, Toloza H, Pérez-Bravo F.

    Nutrition. 2004 Oct;20(10):905-10.PMID: 15474880 [PubMed - indexed for MEDLINE]Related articles

    5.

    Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.

    Ehrmann DA, Tang X, Yoshiuchi I, Cox NJ, Bell GI.

    J Clin Endocrinol Metab. 2002 Sep;87(9):4297-300.PMID: 12213887 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Complex haplotypes of IRS2 gene are associated with severe obesity and reveal heterogeneity in the effect of Gly1057Asp mutation.

    Lautier C, El Mkadem SA, Renard E, Brun JF, Gris JC, Bringer J, Grigorescu F.

    Hum Genet. 2003 Jul;113(1):34-43. Epub 2003 Apr 10.PMID: 12687350 [PubMed - indexed for MEDLINE]Related articles

    7.

    Genetic determinants of insulin action in polycystic ovary syndrome.

    Haap M, Machicao F, Stefan N, Thamer C, Tschritter O, Schnuck F, Wallwiener D, Stumvoll M, Häring HU, Fritsche A.

    Exp Clin Endocrinol Diabetes. 2005 May;113(5):275-81.PMID: 15926113 [PubMed - indexed for MEDLINE]Related articles

    8.

    Polycystic ovary syndrome is associated with genetic polymorphism in the insulin signaling gene IRS-1 but not ENPP1 in a Japanese population.

    Baba T, Endo T, Sata F, Honnma H, Kitajima Y, Hayashi T, Manase K, Kanaya M, Yamada H, Minakami H, Kishi R, Saito T.

    Life Sci. 2007 Aug 16;81(10):850-4. Epub 2007 Aug 7.PMID: 17719609 [PubMed - indexed for MEDLINE]Related articles

    9.

    The importance of IRS-1 Gly972Arg polymorphism in evaluating the response to metformin treatment in polycystic ovary syndrome.

    Ertunc D, Tok EC, Aktas A, Erdal EM, Dilek S.

    Hum Reprod. 2005 May;20(5):1207-12. Epub 2005 Jan 21.PMID: 15665022 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Association of Gly972Arg variant of insulin receptor substrate-1 with metabolic features in women with polycystic ovary syndrome.

    Dilek S, Ertunc D, Tok EC, Erdal EM, Aktas A.

    Fertil Steril. 2005 Aug;84(2):407-12.PMID: 16084882 [PubMed - indexed for MEDLINE]Related articles

    11.

    Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome.

    Yildiz BO, Yarali H, Oguz H, Bayraktar M.

    J Clin Endocrinol Metab. 2003 May;88(5):2031-6.PMID: 12727950 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance.

    Baroni MG, Arca M, Sentinelli F, Buzzetti R, Capici F, Lovari S, Vitale M, Romeo S, Di Mario U.

    Diabetologia. 2001 Mar;44(3):367-72.PMID: 11317670 [PubMed - indexed for MEDLINE]Related articles

    13.

    [Insulin resistance: from clinical diagnosis to molecular genetics. Implications in diabetes mellitus]

    Jaffiol C, Rouard M, Macari F, Lautier C, Ait el Mkadem S, Méchaly I, Brun JF, Renard E, Cros G, Bringer J, Grigorescu F.

    Bull Acad Natl Med. 1999;183(9):1761-75; discussion 1775-7. Review. French. PMID: 10987057 [PubMed - indexed for MEDLINE]Related articles

    14.

    Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes.

    Mammarella S, Romano F, Di Valerio A, Creati B, Esposito DL, Palmirotta R, Capani F, Vitullo P, Volpe G, Battista P, Della Loggia F, Mariani-Costantini R, Cama A.

    Hum Mol Genet. 2000 Oct 12;9(17):2517-21.PMID: 11030756 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Common amino acid substitutions in insulin receptor substrate-4 are not associated with Type II diabetes mellitus or insulin resistance.

    Almind K, Frederiksen SK, Ahlgren MG, Urhammer S, Hansen T, Clausen JO, Pedersen O.

    Diabetologia. 1998 Aug;41(8):969-74.PMID: 9726601 [PubMed - indexed for MEDLINE]Related articles

    16.

    Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in first-degree relatives of subjects with polycystic ovary syndrome.

    Yilmaz M, Ergün MA, Karakoç A, Yurtçu E, Yetkin I, Ayvaz G, Cakir N, Arslan M.

    Gynecol Endocrinol. 2005 Oct;21(4):206-10.PMID: 16316841 [PubMed - indexed for MEDLINE]Related articles

    17.

    New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes.

    Wang H, Rissanen J, Miettinen R, Kärkkäinen P, Kekäläinen P, Kuusisto J, Mykkänen L, Karhapää P, Laakso M.

    Diabetes. 2001 Aug;50(8):1949-51.PMID: 11473060 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    No association between common Gly972Arg variant of the insulin receptor substrate-1 and polycystic ovary syndrome in Southern Chilean women.

    Valdés P, Cerda A, Barrenechea C, Kehr M, Soto C, Salazar LA.

    Clin Chim Acta. 2008 Apr;390(1-2):63-6. Epub 2008 Jan 12.PMID: 18222120 [PubMed - indexed for MEDLINE]Related articles

    19.

    [The influence of polymorphism the Gly972Arg variant insulin receptor substrate-1 (IRS-1) gene, and G-308A TNF-alpha gene on obesity and insulin resistance in children with obesity]

    Pyrzak B, Wiśniewska A, Rymkiewicz-Kluczyńska B.

    Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw. 2006;12(3):175-8. Polish. PMID: 17020651 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    [Genetic aspects of polycystic ovary syndrome]

    Jakubowski L.

    Endokrynol Pol. 2005 May-Jun;56(3):285-93. Review. Polish. PMID: 16350721 [PubMed - indexed for MEDLINE]Related articles

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