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    Results: 1 to 20 of 183

    1.

    Overexpression of metallothionein in pancreatic beta-cells reduces streptozotocin-induced DNA damage and diabetes.

    Chen H, Carlson EC, Pellet L, Moritz JT, Epstein PN.

    Diabetes. 2001 Sep;50(9):2040-6.PMID: 11522669 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Melatonin protects against streptozotocin, but not interleukin-1beta-induced damage of rodent pancreatic beta-cells.

    Andersson AK, Sandler S.

    J Pineal Res. 2001 Apr;30(3):157-65.PMID: 11316326 [PubMed - indexed for MEDLINE]Related articles

    3.

    Poly(ADP-ribose)polymerase activation determines strain sensitivity to streptozotocin-induced beta cell death in inbred mice.

    Cardinal JW, Allan DJ, Cameron DP.

    J Mol Endocrinol. 1999 Feb;22(1):65-70.PMID: 9924181 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Zinc sulphate induces metallothionein in pancreatic islets of mice and protects against diabetes induced by multiple low doses of streptozotocin.

    Ohly P, Dohle C, Abel J, Seissler J, Gleichmann H.

    Diabetologia. 2000 Aug;43(8):1020-30.PMID: 10990080 [PubMed - indexed for MEDLINE]Related articles

    5.

    Curcumin prevents streptozotocin-induced islet damage by scavenging free radicals: a prophylactic and protective role.

    Meghana K, Sanjeev G, Ramesh B.

    Eur J Pharmacol. 2007 Dec 22;577(1-3):183-91. Epub 2007 Sep 11.PMID: 17900558 [PubMed - indexed for MEDLINE]Related articles

    6.

    Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes.

    Masutani M, Suzuki H, Kamada N, Watanabe M, Ueda O, Nozaki T, Jishage K, Watanabe T, Sugimoto T, Nakagama H, Ochiya T, Sugimura T.

    Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2301-4.PMID: 10051636 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species.

    Li X, Chen H, Epstein PN.

    J Biol Chem. 2004 Jan 2;279(1):765-71. Epub 2003 Oct 23.PMID: 14576162 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Transgenic mice expressing IFN-gamma in pancreatic beta-cells are resistant to streptozotocin-induced diabetes.

    Gu D, Arnush M, Sawyer SP, Sarvetnick N.

    Am J Physiol. 1995 Dec;269(6 Pt 1):E1089-94.PMID: 8572201 [PubMed - indexed for MEDLINE]Related articles

    9.

    Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes.

    Pieper AA, Brat DJ, Krug DK, Watkins CC, Gupta A, Blackshaw S, Verma A, Wang ZQ, Snyder SH.

    Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3059-64.PMID: 10077636 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Metallothionein in isolated pancreatic islets of mice: induction by zinc and streptozotocin, a naturally occurring diabetogen.

    Zimny S, Gogolin F, Abel J, Gleichmann H.

    Arch Toxicol. 1993;67(1):61-5.PMID: 8452482 [PubMed - indexed for MEDLINE]Related articles

    11.

    Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme.

    Wold LE, Ceylan-Isik AF, Fang CX, Yang X, Li SY, Sreejayan N, Privratsky JR, Ren J.

    Free Radic Biol Med. 2006 Apr 15;40(8):1419-29. Epub 2006 Jan 6.PMID: 16631532 [PubMed - indexed for MEDLINE]Related articles

    12.

    Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy.

    Cai L, Wang Y, Zhou G, Chen T, Song Y, Li X, Kang YJ.

    J Am Coll Cardiol. 2006 Oct 17;48(8):1688-97. Epub 2006 Sep 27.PMID: 17045908 [PubMed - indexed for MEDLINE]Related articles

    13.

    Novel role of curcumin in the prevention of cytokine-induced islet death in vitro and diabetogenesis in vivo.

    Kanitkar M, Gokhale K, Galande S, Bhonde RR.

    Br J Pharmacol. 2008 Nov;155(5):702-13. Epub 2008 Aug 11.PMID: 18695642 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes.

    Mabley JG, Suarez-Pinzon WL, Haskó G, Salzman AL, Rabinovitch A, Kun E, Szabó C.

    Br J Pharmacol. 2001 Jul;133(6):909-19.PMID: 11454665 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    DNA strand breaks and poly(ADP-ribose) synthetase activation in pancreatic islets--a new aspect to development of insulin-dependent diabetes and pancreatic B-cell tumors.

    Okamoto H, Yamamoto H.

    Princess Takamatsu Symp. 1983;13:297-308.PMID: 6317640 [PubMed - indexed for MEDLINE]Related articles

    16.

    Increased susceptibility to streptozotocin-induced beta-cell apoptosis and delayed autoimmune diabetes in alkylpurine-DNA-N-glycosylase-deficient mice.

    Cardinal JW, Margison GP, Mynett KJ, Yates AP, Cameron DP, Elder RH.

    Mol Cell Biol. 2001 Aug;21(16):5605-13.PMID: 11463841 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Prevention of type 1 diabetes: from the view point of beta cell damage.

    Kawasaki E, Abiru N, Eguchi K.

    Diabetes Res Clin Pract. 2004 Dec;66 Suppl 1:S27-32. Review.PMID: 15563975 [PubMed - indexed for MEDLINE]Related articles

    18.

    Differential metabolite accumulation may be the cause of strain differences in sensitivity to streptozotocin-induced beta cell death in inbred mice.

    Cardinal JW, Allan DJ, Cameron DP.

    Endocrinology. 1998 Jun;139(6):2885-91.PMID: 9607798 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Metallothionein: in vitro induction with zinc and streptozotocin in pancreatic islets of mice.

    Ohly P, Gleichmann H.

    Exp Clin Endocrinol Diabetes. 1995;103 Suppl 2:79-82.PMID: 8839259 [PubMed - indexed for MEDLINE]Related articles

    20.

    Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes-induced cardiac injury.

    Song Y, Wang J, Li Y, Du Y, Arteel GE, Saari JT, Kang YJ, Cai L.

    Am J Pathol. 2005 Jul;167(1):17-26.PMID: 15972948 [PubMed - indexed for MEDLINE]Related articlesFree article

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