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    Results: 1 to 20 of 253

    1.

    Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.

    Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S.

    Diabetes. 2001 Sep;50(9):1992-2000.PMID: 11522664 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions.

    Graser RT, DiLorenzo TP, Wang F, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV.

    J Immunol. 2000 Apr 1;164(7):3913-8.PMID: 10725754 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice.

    Kanagawa O, Shimizu J, Vaupel BA.

    J Immunol. 2000 May 15;164(10):5466-73.PMID: 10799914 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice.

    Verdaguer J, Schmidt D, Amrani A, Anderson B, Averill N, Santamaria P.

    J Exp Med. 1997 Nov 17;186(10):1663-76.PMID: 9362527 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice.

    Serreze DV, Choisy-Rossi CM, Grier AE, Holl TM, Chapman HD, Gahagan JR, Osborne MA, Zhang W, King BL, Brown A, Roopenian D, Marron MP.

    J Immunol. 2008 Mar 1;180(5):3250-9.PMID: 18292549 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.

    Serreze DV, Holl TM, Marron MP, Graser RT, Johnson EA, Choisy-Rossi C, Slattery RM, Lieberman SM, DiLorenzo TP.

    J Immunol. 2004 Jan 15;172(2):871-9.PMID: 14707058 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Genetic and therapeutic control of diabetogenic CD8+ T cells.

    Santamaria P.

    Novartis Found Symp. 2008;292:130-6; discussion 136-45, 202-3.PMID: 19209463 [PubMed - indexed for MEDLINE]Related articles

    8.

    Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains.

    Verdaguer J, Yoon JW, Anderson B, Averill N, Utsugi T, Park BJ, Santamaria P.

    J Immunol. 1996 Nov 15;157(10):4726-35.PMID: 8906855 [PubMed - indexed for MEDLINE]Related articles

    9.

    Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens.

    Yamanouchi J, Verdaguer J, Han B, Amrani A, Serra P, Santamaria P.

    J Immunol. 2003 Dec 15;171(12):6900-9.PMID: 14662897 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer.

    Tarbell KV, Lee M, Ranheim E, Chao CC, Sanna M, Kim SK, Dickie P, Teyton L, Davis M, McDevitt H.

    J Exp Med. 2002 Aug 19;196(4):481-92.PMID: 12186840 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice.

    Hultcrantz M, Jacobson S, Hill NJ, Santamaria P, Flodström-Tullberg M.

    Diabetologia. 2009 Feb;52(2):299-305. Epub 2008 Nov 25.PMID: 19031069 [PubMed - indexed for MEDLINE]Related articles

    12.

    Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice.

    Chen YG, Scheuplein F, Osborne MA, Tsaih SW, Chapman HD, Serreze DV.

    Diabetes. 2008 Dec;57(12):3273-80. Epub 2008 Sep 5.PMID: 18776136 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC gene-controlled near death experience.

    Choisy-Rossi CM, Holl TM, Pierce MA, Chapman HD, Serreze DV.

    J Immunol. 2004 Sep 15;173(6):3791-800.PMID: 15356126 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.

    Anderson B, Park BJ, Verdaguer J, Amrani A, Santamaria P.

    Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9311-6.PMID: 10430939 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Evidence for a preferential V beta usage by the T cells which adoptively transfer diabetes in NOD mice.

    Edouard P, Thivolet C, Bedossa P, Olivi M, Legrand B, Bendelac A, Bach JF, Carnaud C.

    Eur J Immunol. 1993 Mar;23(3):727-33.PMID: 8095459 [PubMed - indexed for MEDLINE]Related articles

    16.

    Regulation of diabetes development by regulatory T cells in pancreatic islet antigen-specific TCR transgenic nonobese diabetic mice.

    Kanagawa O, Militech A, Vaupel BA.

    J Immunol. 2002 Jun 15;168(12):6159-64.PMID: 12055228 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas.

    Dai YD, Jensen KP, Lehuen A, Masteller EL, Bluestone JA, Wilson DB, Sercarz EE.

    J Immunol. 2005 Sep 15;175(6):3621-7.PMID: 16148106 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Protection from type 1 diabetes in the face of high levels of activated autoaggressive lymphocytes in a viral transgenic mouse model crossed to the SV129 strain.

    von Herrath MG, Wolfe T, Möhrle U, Coon B, Hughes A.

    Diabetes. 2001 Dec;50(12):2700-8.PMID: 11723052 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

    Hammond KJ, Poulton LD, Palmisano LJ, Silveira PA, Godfrey DI, Baxter AG.

    J Exp Med. 1998 Apr 6;187(7):1047-56.PMID: 9529321 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes.

    Takaki T, Marron MP, Mathews CE, Guttmann ST, Bottino R, Trucco M, DiLorenzo TP, Serreze DV.

    J Immunol. 2006 Mar 1;176(5):3257-65.PMID: 16493087 [PubMed - indexed for MEDLINE]Related articlesFree article

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