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    Results: 1 to 20 of 188

    1.

    A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice.

    Roduit R, Masiello P, Wang SP, Li H, Mitchell GA, Prentki M.

    Diabetes. 2001 Sep;50(9):1970-5.PMID: 11522661 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1.

    Peyot ML, Nolan CJ, Soni K, Joly E, Lussier R, Corkey BE, Wang SP, Mitchell GA, Prentki M.

    Diabetes. 2004 Jul;53(7):1733-42.PMID: 15220197 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis.

    Fex M, Haemmerle G, Wierup N, Dekker-Nitert M, Rehn M, Ristow M, Zechner R, Sundler F, Holm C, Eliasson L, Mulder H.

    Diabetologia. 2009 Feb;52(2):271-80. Epub 2008 Nov 21.PMID: 19023560 [PubMed - indexed for MEDLINE]Related articles

    4.

    Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion.

    Peyot ML, Guay C, Latour MG, Lamontagne J, Lussier R, Pineda M, Ruderman NB, Haemmerle G, Zechner R, Joly E, Madiraju SR, Poitout V, Prentki M.

    J Biol Chem. 2009 Jun 19;284(25):16848-59. Epub 2009 Apr 22.PMID: 19389712 [PubMed - indexed for MEDLINE]Related articles

    5.

    Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact.

    Fex M, Olofsson CS, Fransson U, Bacos K, Lindvall H, Sörhede-Winzell M, Rorsman P, Holm C, Mulder H.

    Endocrinology. 2004 Aug;145(8):3746-53. Epub 2004 May 13.PMID: 15142983 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.

    Sekiya M, Yahagi N, Tamura Y, Okazaki H, Igarashi M, Ohta K, Takanashi M, Kumagai M, Takase S, Nishi M, Takeuchi Y, Izumida Y, Kubota M, Ohashi K, Iizuka Y, Yagyu H, Gotoda T, Nagai R, Shimano H, Yamada N, Kadowaki T, Ishibashi S, Osuga J.

    Biochem Biophys Res Commun. 2009 Sep 25;387(3):511-5. Epub 2009 Jul 18.PMID: 19619509 [PubMed - indexed for MEDLINE]Related articles

    7.

    Glucagon-like peptide-1 and islet lipolysis.

    Sörhede Winzell M, Ahrén B.

    Horm Metab Res. 2004 Nov-Dec;36(11-12):795-803.PMID: 15655711 [PubMed - indexed for MEDLINE]Related articles

    8.

    Lipases in the pancreatic beta-cell: implications for insulin secretion.

    Fex M, Mulder H.

    Biochem Soc Trans. 2008 Oct;36(Pt 5):885-90. Review.PMID: 18793156 [PubMed - indexed for MEDLINE]Related articles

    9.

    Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes.

    Hu L, Deeney JT, Nolan CJ, Peyot ML, Ao A, Richard AM, Luc E, Faergeman NJ, Knudsen J, Guo W, Sorhede-Winzell M, Prentki M, Corkey BE.

    Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1085-92. Epub 2005 Aug 9.PMID: 16091387 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice.

    Voshol PJ, Haemmerle G, Ouwens DM, Zimmermann R, Zechner R, Teusink B, Maassen JA, Havekes LM, Romijn JA.

    Endocrinology. 2003 Aug;144(8):3456-62.PMID: 12865325 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Lack of cholesterol mobilization in islets of hormone-sensitive lipase deficient mice impairs insulin secretion.

    Larsson S, Wierup N, Sundler F, Eliasson L, Holm C.

    Biochem Biophys Res Commun. 2008 Nov 21;376(3):558-62. Epub 2008 Sep 18.PMID: 18804448 [PubMed - indexed for MEDLINE]Related articles

    12.

    Regulation of hormone-sensitive lipase in islets.

    Shen WJ, Liang Y, Wang J, Harada K, Patel S, Michie SA, Osuga J, Ishibashi S, Kraemer FB.

    Diabetes Res Clin Pract. 2007 Jan;75(1):14-26. Epub 2006 Jun 9.PMID: 16765472 [PubMed - indexed for MEDLINE]Related articles

    13.

    Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact.

    Mulder H, Sörhede-Winzell M, Contreras JA, Fex M, Ström K, Ploug T, Galbo H, Arner P, Lundberg C, Sundler F, Ahrén B, Holm C.

    J Biol Chem. 2003 Sep 19;278(38):36380-8. Epub 2003 Jun 30.PMID: 12835327 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart.

    Park SY, Kim HJ, Wang S, Higashimori T, Dong J, Kim YJ, Cline G, Li H, Prentki M, Shulman GI, Mitchell GA, Kim JK.

    Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E30-9. Epub 2005 Feb 8.PMID: 15701680 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase.

    Winzell MS, Svensson H, Enerbäck S, Ravnskjaer K, Mandrup S, Esser V, Arner P, Alves-Guerra MC, Miroux B, Sundler F, Ahrén B, Holm C.

    Diabetes. 2003 Aug;52(8):2057-65.PMID: 12882923 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Hormone-sensitive lipase-independent adipocyte lipolysis during beta-adrenergic stimulation, fasting, and dietary fat loading.

    Fortier M, Wang SP, Mauriège P, Semache M, Mfuma L, Li H, Levy E, Richard D, Mitchell GA.

    Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E282-8.PMID: 15271647 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose.

    Winzell MS, Svensson H, Arner P, Ahrén B, Holm C.

    Diabetes. 2001 Oct;50(10):2225-30.PMID: 11574402 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis.

    Reid BN, Ables GP, Otlivanchik OA, Schoiswohl G, Zechner R, Blaner WS, Goldberg IJ, Schwabe RF, Chua SC Jr, Huang LS.

    J Biol Chem. 2008 May 9;283(19):13087-99. Epub 2008 Mar 12.PMID: 18337240 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose.

    Claus TH, Lowe DB, Liang Y, Salhanick AI, Lubeski CK, Yang L, Lemoine L, Zhu J, Clairmont KB.

    J Pharmacol Exp Ther. 2005 Dec;315(3):1396-402. Epub 2005 Sep 14.PMID: 16162821 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise.

    Fernandez C, Hansson O, Nevsten P, Holm C, Klint C.

    Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E179-86. Epub 2008 May 20.PMID: 18492774 [PubMed - indexed for MEDLINE]Related articlesFree article

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