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    Results: 1 to 20 of 766

    1.

    Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes.

    Takano A, Haruta T, Iwata M, Usui I, Uno T, Kawahara J, Ueno E, Sasaoka T, Kobayashi M.

    Diabetes. 2001 Aug;50(8):1891-900.PMID: 11473053 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.

    Tremblay F, Gagnon A, Veilleux A, Sorisky A, Marette A.

    Endocrinology. 2005 Mar;146(3):1328-37. Epub 2004 Dec 2.PMID: 15576463 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes.

    Ishibashi KI, Imamura T, Sharma PM, Huang J, Ugi S, Olefsky JM.

    J Clin Invest. 2001 May;107(9):1193-202.PMID: 11342583 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance.

    Egawa K, Sharma PM, Nakashima N, Huang Y, Huver E, Boss GR, Olefsky JM.

    J Biol Chem. 1999 May 14;274(20):14306-14.PMID: 10318852 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP.

    Hresko RC, Heimberg H, Chi MM, Mueckler M.

    J Biol Chem. 1998 Aug 7;273(32):20658-68.PMID: 9685425 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes.

    Egawa K, Nakashima N, Sharma PM, Maegawa H, Nagai Y, Kashiwagi A, Kikkawa R, Olefsky JM.

    Endocrinology. 2000 Jun;141(6):1930-5.PMID: 10830273 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes.

    Fasshauer M, Klein J, Ueki K, Kriauciunas KM, Benito M, White MF, Kahn CR.

    J Biol Chem. 2000 Aug 18;275(33):25494-501.PMID: 10829031 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction.

    Sakoda H, Ogihara T, Anai M, Funaki M, Inukai K, Katagiri H, Fukushima Y, Onishi Y, Ono H, Fujishiro M, Kikuchi M, Oka Y, Asano T.

    Diabetes. 2000 Oct;49(10):1700-8.PMID: 11016454 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Insulin receptor substrate-1 enhances growth hormone-induced proliferation.

    Liang L, Zhou T, Jiang J, Pierce JH, Gustafson TA, Frank SJ.

    Endocrinology. 1999 May;140(5):1972-83.PMID: 10218944 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action.

    Sharma PM, Egawa K, Huang Y, Martin JL, Huvar I, Boss GR, Olefsky JM.

    J Biol Chem. 1998 Jul 17;273(29):18528-37.PMID: 9660823 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.

    Iwata M, Haruta T, Usui I, Takata Y, Takano A, Uno T, Kawahara J, Ueno E, Sasaoka T, Ishibashi O, Kobayashi M.

    Diabetes. 2001 May;50(5):1083-92.PMID: 11334412 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes.

    Mahadev K, Wu X, Zilbering A, Zhu L, Lawrence JT, Goldstein BJ.

    J Biol Chem. 2001 Dec 28;276(52):48662-9. Epub 2001 Oct 11.PMID: 11598110 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Engagement of the insulin-sensitive pathway in the stimulation of glucose transport by alpha-lipoic acid in 3T3-L1 adipocytes.

    Yaworsky K, Somwar R, Ramlal T, Tritschler HJ, Klip A.

    Diabetologia. 2000 Mar;43(3):294-303.PMID: 10768090 [PubMed - indexed for MEDLINE]Related articles

    15.

    Defective Akt activation is associated with glucose- but not glucosamine-induced insulin resistance.

    Nelson BA, Robinson KA, Buse MG.

    Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E497-506.PMID: 11832350 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation.

    Venable CL, Frevert EU, Kim YB, Fischer BM, Kamatkar S, Neel BG, Kahn BB.

    J Biol Chem. 2000 Jun 16;275(24):18318-26.PMID: 10751417 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.

    Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M.

    Mol Cell Biol. 2001 Mar;21(5):1633-46.PMID: 11238900 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes.

    Kotani K, Ogawa W, Matsumoto M, Kitamura T, Sakaue H, Hino Y, Miyake K, Sano W, Akimoto K, Ohno S, Kasuga M.

    Mol Cell Biol. 1998 Dec;18(12):6971-82.PMID: 9819385 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

    Summers SA, Garza LA, Zhou H, Birnbaum MJ.

    Mol Cell Biol. 1998 Sep;18(9):5457-64.PMID: 9710629 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes.

    Fasshauer M, Klein J, Kriauciunas KM, Ueki K, Benito M, Kahn CR.

    Mol Cell Biol. 2001 Jan;21(1):319-29.PMID: 11113206 [PubMed - indexed for MEDLINE]Related articlesFree article

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