PubMed

Proteins linked to a protein transduction domain efficiently transduce pancreatic islets.

Embury J, Klein D, Pileggi A, Ribeiro M, Jayaraman S, Molano RD, Fraker C, Kenyon N, Ricordi C, Inverardi L, Pastori RL.

Diabetes. 2001 Aug;50(8):1706-13.PMID: 11473028 [PubMed - indexed for MEDLINE]Related articlesFree article

Delivery of TAT/PTD-fused proteins/peptides to islets via pancreatic duct.

Klein D, Mendoza V, Pileggi A, Molano RD, Barbé-Tuana FM, Inverardi L, Ricordi C, Pastori RL.

Cell Transplant. 2005;14(5):241-8.PMID: 16052906 [PubMed - indexed for MEDLINE]Related articles

Cytoprotection of pancreatic islets before and soon after transplantation by gene transfer of the anti-apoptotic Bcl-2 gene.

Contreras JL, Bilbao G, Smyth CA, Jiang XL, Eckhoff DE, Jenkins SM, Thomas FT, Curiel DT, Thomas JM.

Transplantation. 2001 Apr 27;71(8):1015-23.PMID: 11374395 [PubMed - indexed for MEDLINE]Related articles

Heme oxygenase-1 fused to a TAT peptide transduces and protects pancreatic beta-cells.

Ribeiro MM, Klein D, Pileggi A, Molano RD, Fraker C, Ricordi C, Inverardi L, Pastori RL.

Biochem Biophys Res Commun. 2003 Jun 13;305(4):876-81.PMID: 12767912 [PubMed - indexed for MEDLINE]Related articles

Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets.

Klein D, Ribeiro MM, Mendoza V, Jayaraman S, Kenyon NS, Pileggi A, Molano RD, Inverardi L, Ricordi C, Pastori RL.

Biochem Biophys Res Commun. 2004 Oct 15;323(2):473-8.PMID: 15369775 [PubMed - indexed for MEDLINE]Related articles

Genetically modified adenovirus vector containing an RGD peptide in the HI loop of the fiber knob improves gene transfer to nonhuman primate isolated pancreatic islets.

Bilbao G, Contreras JL, Dmitriev I, Smyth CA, Jenkins S, Eckhoff D, Thomas F, Thomas J, Curiel DT.

Am J Transplant. 2002 Mar;2(3):237-43.PMID: 12096786 [PubMed - indexed for MEDLINE]Related articles

HIV-1 Tat-mediated protein transduction of Cu,Zn-superoxide dismutase into pancreatic beta cells in vitro and in vivo.

Eum WS, Choung IS, Li MZ, Kang JH, Kim DW, Park J, Kwon HY, Choi SY.

Free Radic Biol Med. 2004 Aug 1;37(3):339-49.PMID: 15223067 [PubMed - indexed for MEDLINE]Related articles

Adenoviral transfection of isolated pancreatic islets: a study of programmed cell death (apoptosis) and islet function.

Weber M, Deng S, Kucher T, Shaked A, Ketchum RJ, Brayman KL.

J Surg Res. 1997 Apr;69(1):23-32.PMID: 9202642 [PubMed - indexed for MEDLINE]Related articles

Long-term gene expression and metabolic control exerted by lentivirus-transduced pancreatic islets.

He Z, Wang F, Kumagai-Braesch M, Permert J, Holgersson J.

Xenotransplantation. 2006 May;13(3):195-203.PMID: 16756562 [PubMed - indexed for MEDLINE]Related articles

In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis.

Cao G, Pei W, Ge H, Liang Q, Luo Y, Sharp FR, Lu A, Ran R, Graham SH, Chen J.

J Neurosci. 2002 Jul 1;22(13):5423-31.PMID: 12097494 [PubMed - indexed for MEDLINE]Related articlesFree article

The kinetics and tissue distribution of protein transduction in mice.

Cai SR, Xu G, Becker-Hapak M, Ma M, Dowdy SF, McLeod HL.

Eur J Pharm Sci. 2006 Mar;27(4):311-9. Epub 2006 Jan 11.PMID: 16376528 [PubMed - indexed for MEDLINE]Related articles

Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.

Piro S, Anello M, Di Pietro C, Lizzio MN, Patanè G, Rabuazzo AM, Vigneri R, Purrello M, Purrello F.

Metabolism. 2002 Oct;51(10):1340-7.PMID: 12370856 [PubMed - indexed for MEDLINE]Related articles

XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes.

Emamaullee JA, Rajotte RV, Liston P, Korneluk RG, Lakey JR, Shapiro AM, Elliott JF.

Diabetes. 2005 Sep;54(9):2541-8.PMID: 16123341 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors1.

Curran MA, Ochoa MS, Molano RD, Pileggi A, Inverardi L, Kenyon NS, Nolan GP, Ricordi C, Fenjves ES.

Transplantation. 2002 Aug 15;74(3):299-306.PMID: 12177606 [PubMed - indexed for MEDLINE]Related articles

Gene transfer of the Bcl-2 gene confers cytoprotection to isolated adult porcine pancreatic islets exposed to xenoreactive antibodies and complement.

Contreras JL, Bilbao G, Smyth C, Eckhoff DE, Xiang XL, Jenkins S, Cartner S, Curiel DT, Thomas FT, Thomas JM.

Surgery. 2001 Aug;130(2):166-74.PMID: 11490345 [PubMed - indexed for MEDLINE]Related articles

Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice.

Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Chen Y, Yuasa T, Tanaka K, Narushima M, Miki A, Misawa H, Tabata Y, Jun HS, Matsumoto S, Fox IJ, Tanaka N, Kobayashi N.

Diabetes. 2007 May;56(5):1259-67. Epub 2007 Feb 7.PMID: 17287463 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection of islets in culture by delivery of oxygen binding neuroglobin via protein transduction.

Mendoza V, Klein D, Ichii H, Ribeiro MM, Ricordi C, Hankeln T, Burmester T, Pastori RL.

Transplant Proc. 2005 Jan-Feb;37(1):237-40.PMID: 15808606 [PubMed - indexed for MEDLINE]Related articles

Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death.

Garcia-Ocana A, Takane KK, Reddy VT, Lopez-Talavera JC, Vasavada RC, Stewart AF.

J Biol Chem. 2003 Jan 3;278(1):343-51. Epub 2002 Oct 25.PMID: 12403787 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function.

Noguchi H, Nakai Y, Matsumoto S, Kawaguchi M, Ueda M, Okitsu T, Iwanaga Y, Yonekawa Y, Nagata H, Minami K, Masui Y, Futaki S, Tanaka K.

Am J Transplant. 2005 Aug;5(8):1848-55.PMID: 15996231 [PubMed - indexed for MEDLINE]Related articles

Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice.

Rao P, Roccisana J, Takane KK, Bottino R, Zhao A, Trucco M, García-Ocaña A.

Diabetes. 2005 Jun;54(6):1664-75.PMID: 15919787 [PubMed - indexed for MEDLINE]Related articlesFree article