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    Results: 1 to 20 of 136

    1.

    Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets.

    Maedler K, Spinas GA, Lehmann R, Sergeev P, Weber M, Fontana A, Kaiser N, Donath MY.

    Diabetes. 2001 Aug;50(8):1683-90.PMID: 11473025 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication.

    Maedler K, Fontana A, Ris F, Sergeev P, Toso C, Oberholzer J, Lehmann R, Bachmann F, Tasinato A, Spinas GA, Halban PA, Donath MY.

    Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8236-41.PMID: 12060768 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Cytokines activate caspase-3 in insulinoma cells of diabetes-prone NOD mice directly and via upregulation of Fas.

    Augstein P, Bahr J, Wachlin G, Heinke P, Berg S, Salzsieder E, Harrison LC.

    J Autoimmun. 2004 Dec;23(4):301-9.PMID: 15571924 [PubMed - indexed for MEDLINE]Related articles

    4.

    Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1.

    Maedler K, Schumann DM, Schulthess F, Oberholzer J, Bosco D, Berney T, Donath MY.

    Diabetes. 2006 Sep;55(9):2455-62.PMID: 16936193 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells.

    Liu JJ, Nilsson A, Oredsson S, Badmaev V, Zhao WZ, Duan RD.

    Carcinogenesis. 2002 Dec;23(12):2087-93.PMID: 12507932 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?

    Welsh N, Cnop M, Kharroubi I, Bugliani M, Lupi R, Marchetti P, Eizirik DL.

    Diabetes. 2005 Nov;54(11):3238-44.PMID: 16249450 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Zeta-associated protein of 70 kDa (ZAP-70), but not Syk, tyrosine kinase can mediate apoptosis of T cells through the Fas/Fas ligand, caspase-8 and caspase-3 pathways.

    Zhong L, Wu CH, Lee WH, Liu CP.

    J Immunol. 2004 Feb 1;172(3):1472-82.PMID: 14734724 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Fas and Fas ligand expression in inflamed islets in pancreas sections of patients with recent-onset Type I diabetes mellitus.

    Moriwaki M, Itoh N, Miyagawa J, Yamamoto K, Imagawa A, Yamagata K, Iwahashi H, Nakajima H, Namba M, Nagata S, Hanafusa T, Matsuzawa Y.

    Diabetologia. 1999 Nov;42(11):1332-40.PMID: 10550417 [PubMed - indexed for MEDLINE]Related articles

    9.

    Cryptosporidium parvum induces apoptosis in biliary epithelia by a Fas/Fas ligand-dependent mechanism.

    Chen XM, Gores GJ, Paya CV, LaRusso NF.

    Am J Physiol. 1999 Sep;277(3 Pt 1):G599-608.PMID: 10484385 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Expression of Fas but not Fas ligand on fetal pig beta cells.

    Bai L, Maedler K, Donath M, Tuch BE.

    Xenotransplantation. 2004 Sep;11(5):426-35.PMID: 15303979 [PubMed - indexed for MEDLINE]Related articles

    11.

    Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets.

    Maedler K, Sergeev P, Ris F, Oberholzer J, Joller-Jemelka HI, Spinas GA, Kaiser N, Halban PA, Donath MY.

    J Clin Invest. 2002 Sep;110(6):851-60.PMID: 12235117 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Mechanisms of accelerated immune-mediated diabetes resulting from islet beta cell expression of a Fas ligand transgene.

    Silva DG, Petrovsky N, Socha L, Slattery R, Gatenby P, Charlton B.

    J Immunol. 2003 May 15;170(10):4996-5002.PMID: 12734343 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Fas ligand down-regulates cytokine-induced Fas receptor expression on insulinoma (NIT-1), but not islet cells, from autoimmune nonobese diabetic mice.

    Augstein P, Heinke P, Salzsieder E, Berg S, Rettig R, Salzsieder C, Harrison LC.

    Endocrinology. 2004 Jun;145(6):2747-52. Epub 2004 Mar 19.PMID: 15033908 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Expression of apoptosis markers in the retinas of human subjects with diabetes.

    Abu-El-Asrar AM, Dralands L, Missotten L, Al-Jadaan IA, Geboes K.

    Invest Ophthalmol Vis Sci. 2004 Aug;45(8):2760-6.PMID: 15277502 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Autoimmune diabetes in the NOD mouse: an essential role of Fas-FasL signaling in beta cell apoptosis.

    Silva DG, Socha L, Charlton B, Cowden W, Petrovsky N.

    Ann N Y Acad Sci. 2003 Nov;1005:161-5.PMID: 14679051 [PubMed - indexed for MEDLINE]Related articles

    16.

    Progesterone-induced apoptosis in immortalized normal and malignant human ovarian surface epithelial cells involves enhanced expression of FasL.

    Syed V, Ho SM.

    Oncogene. 2003 Oct 9;22(44):6883-90.PMID: 14534535 [PubMed - indexed for MEDLINE]Related articles

    17.

    Fas/Fas ligand interactions play an essential role in the initiation of murine autoimmune diabetes.

    Nakayama M, Nagata M, Yasuda H, Arisawa K, Kotani R, Yamada K, Chowdhury SA, Chakrabarty S, Jin ZZ, Yagita H, Yokono K, Kasuga M.

    Diabetes. 2002 May;51(5):1391-7.PMID: 11978635 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Fas and Fas ligand immunolocalization in pancreatic islets of NOD mice during spontaneous and cyclophosphamide-accelerated diabetes.

    Redd S, Ginn S, Ross JM.

    Histochem J. 2002 Jan-Feb;34(1-2):1-12.PMID: 12365794 [PubMed - indexed for MEDLINE]Related articles

    19.

    Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.

    Piro S, Anello M, Di Pietro C, Lizzio MN, Patanè G, Rabuazzo AM, Vigneri R, Purrello M, Purrello F.

    Metabolism. 2002 Oct;51(10):1340-7.PMID: 12370856 [PubMed - indexed for MEDLINE]Related articles

    20.

    A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages.

    Li HL, Wang AB, Zhang R, Wei YS, Chen HZ, She ZG, Huang Y, Liu DP, Liang CC.

    J Cell Physiol. 2006 Aug;208(2):307-18.PMID: 16646083 [PubMed - indexed for MEDLINE]Related articles

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