PubMed

Glucose effects on skin keratinocytes: implications for diabetes skin complications.

Spravchikov N, Sizyakov G, Gartsbein M, Accili D, Tennenbaum T, Wertheimer E.

Diabetes. 2001 Jul;50(7):1627-35.PMID: 11423485 [PubMed - indexed for MEDLINE]Related articlesFree article

The regulation of skin proliferation and differentiation in the IR null mouse: implications for skin complications of diabetes.

Wertheimer E, Spravchikov N, Trebicz M, Gartsbein M, Accili D, Avinoah I, Nofeh-Moses S, Sizyakov G, Tennenbaum T.

Endocrinology. 2001 Mar;142(3):1234-41.PMID: 11181540 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential roles of insulin receptor and insulin-like growth factor-1 receptor in differentiation of murine skin keratinocytes.

Wertheimer E, Trebicz M, Eldar T, Gartsbein M, Nofeh-Moses S, Tennenbaum T.

J Invest Dermatol. 2000 Jul;115(1):24-9.PMID: 10886503 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of glucose transport system in keratinocytes: insulin and IGF-1 differentially affect specific transporters.

Shen S, Wertheimer E, Sampson SR, Tennenbaum T.

J Invest Dermatol. 2000 Dec;115(6):949-54.PMID: 11121124 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased IGFR activity and glucose transport in cultured skeletal muscle from insulin receptor null mice.

Shefi-Friedman L, Wertheimer E, Shen S, Bak A, Accili D, Sampson SR.

Am J Physiol Endocrinol Metab. 2001 Jul;281(1):E16-24.PMID: 11404219 [PubMed - indexed for MEDLINE]Related articlesFree article

Matrix metalloproteinase 19 regulates insulin-like growth factor-mediated proliferation, migration, and adhesion in human keratinocytes through proteolysis of insulin-like growth factor binding protein-3.

Sadowski T, Dietrich S, Koschinsky F, Sedlacek R.

Mol Biol Cell. 2003 Nov;14(11):4569-80. Epub 2003 Aug 22.PMID: 12937269 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes.

Nevado C, Valverde AM, Benito M.

Endocrinology. 2006 Aug;147(8):3709-18. Epub 2006 Apr 27.PMID: 16644916 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation.

Sadagurski M, Yakar S, Weingarten G, Holzenberger M, Rhodes CJ, Breitkreutz D, Leroith D, Wertheimer E.

Mol Cell Biol. 2006 Apr;26(7):2675-87.PMID: 16537911 [PubMed - indexed for MEDLINE]Related articlesFree article

PKCdelta activation: a divergence point in the signaling of insulin and IGF-1-induced proliferation of skin keratinocytes.

Shen S, Alt A, Wertheimer E, Gartsbein M, Kuroki T, Ohba M, Braiman L, Sampson SR, Tennenbaum T.

Diabetes. 2001 Feb;50(2):255-64.PMID: 11272134 [PubMed - indexed for MEDLINE]Related articlesFree article

D-glucose stimulates mesangial cell GLUT1 expression and basal and IGF-I-sensitive glucose uptake in rat mesangial cells: implications for diabetic nephropathy.

Heilig CW, Liu Y, England RL, Freytag SO, Gilbert JD, Heilig KO, Zhu M, Concepcion LA, Brosius FC 3rd.

Diabetes. 1997 Jun;46(6):1030-9.PMID: 9166676 [PubMed - indexed for MEDLINE]Related articles

Maintenance of human skin in organ culture: role for insulin-like growth factor-1 receptor and epidermal growth factor receptor.

Tavakkol A, Varani J, Elder JT, Zouboulis CC.

Arch Dermatol Res. 1999 Dec;291(12):643-51.PMID: 10651165 [PubMed - indexed for MEDLINE]Related articles

Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation.

Mur C, Arribas M, Benito M, Valverde AM.

Endocrinology. 2003 Feb;144(2):581-93.PMID: 12538620 [PubMed - indexed for MEDLINE]Related articlesFree article

The insulin-sensitive glucose transporter (GLUT4) is involved in early bone growth in control and diabetic mice, but is regulated through the insulin-like growth factor I receptor.

Maor G, Karnieli E.

Endocrinology. 1999 Apr;140(4):1841-51.PMID: 10098523 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse keratinocytes express c98, a novel gene homologous to bcl-2, that is stimulated by insulin-like growth factor 1 and prevents dexamethasone-induced apoptosis.

Su HY, Cheng WT, Chen SC, Lin CT, Lien YY, Liu HJ, Gilmour RS.

Biochim Biophys Acta. 2004 Jan 20;1676(2):127-37.PMID: 14746907 [PubMed - indexed for MEDLINE]Related articles

High glucose and insulin in combination cause insulin receptor substrate-1 and -2 depletion and protein kinase B desensitisation in primary cultured rat adipocytes: possible implications for insulin resistance in type 2 diabetes.

Burén J, Liu HX, Lauritz J, Eriksson JW.

Eur J Endocrinol. 2003 Jan;148(1):157-67.PMID: 12534369 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor I receptors are more abundant than insulin receptors in human micro- and macrovascular endothelial cells.

Chisalita SI, Arnqvist HJ.

Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E896-901. Epub 2004 Jan 13.PMID: 14722023 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of insulin-like growth factor I on the development of osteoblasts in hyperglycemia.

Fang Y, Wang ZY, Mao Y, Xin HT, Ren GL, Bai XF.

Diabetes Res Clin Pract. 2006 Jul;73(1):95-7. Epub 2006 Jan 18.PMID: 16413942 [PubMed - indexed for MEDLINE]Related articles

Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action.

Fulzele K, DiGirolamo DJ, Liu Z, Xu J, Messina JL, Clemens TL.

J Biol Chem. 2007 Aug 31;282(35):25649-58. Epub 2007 Jun 6.PMID: 17553792 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo.

Ji QS, Mulvihill MJ, Rosenfeld-Franklin M, Cooke A, Feng L, Mak G, O'Connor M, Yao Y, Pirritt C, Buck E, Eyzaguirre A, Arnold LD, Gibson NW, Pachter JA.

Mol Cancer Ther. 2007 Aug;6(8):2158-67. Epub 2007 Aug 1.PMID: 17671083 [PubMed - indexed for MEDLINE]Related articlesFree article

The suppressor of cytokine signaling-3 is upregulated in impaired skin repair: implications for keratinocyte proliferation.

Goren I, Linke A, Müller E, Pfeilschifter J, Frank S.

J Invest Dermatol. 2006 Feb;126(2):477-85.PMID: 16374465 [PubMed - indexed for MEDLINE]Related articlesFree article