PubMed

Glucagon-like peptide-1 and exendin-4 stimulate beta-cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age.

Tourrel C, Bailbé D, Meile MJ, Kergoat M, Portha B.

Diabetes. 2001 Jul;50(7):1562-70.PMID: 11423477 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4.

Tourrel C, Bailbe D, Lacorne M, Meile MJ, Kergoat M, Portha B.

Diabetes. 2002 May;51(5):1443-52.PMID: 11978641 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis.

Li Y, Hansotia T, Yusta B, Ris F, Halban PA, Drucker DJ.

J Biol Chem. 2003 Jan 3;278(1):471-8. Epub 2002 Oct 29.PMID: 12409292 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats.

Perfetti R, Zhou J, Doyle ME, Egan JM.

Endocrinology. 2000 Dec;141(12):4600-5.PMID: 11108273 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1(7-36)-amide confers glucose sensitivity to previously glucose-incompetent beta-cells in diabetic rats: in vivo and in vitro studies.

Dachicourt N, Serradas P, Bailbé D, Kergoat M, Doaré L, Portha B.

J Endocrinol. 1997 Nov;155(2):369-76.PMID: 9415071 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro.

Parkes DG, Pittner R, Jodka C, Smith P, Young A.

Metabolism. 2001 May;50(5):583-9.PMID: 11319721 [PubMed - indexed for MEDLINE]Related articles

Effects of glucagon-like peptide-1 and exendins on kinase activity, glucose transport and lipid metabolism in adipocytes from normal and type-2 diabetic rats.

Sancho V, Trigo MV, González N, Valverde I, Malaisse WJ, Villanueva-Peñacarrillo ML.

J Mol Endocrinol. 2005 Aug;35(1):27-38.PMID: 16087719 [PubMed - indexed for MEDLINE]Related articlesFree article

Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.

Pospisilik JA, Martin J, Doty T, Ehses JA, Pamir N, Lynn FC, Piteau S, Demuth HU, McIntosh CH, Pederson RA.

Diabetes. 2003 Mar;52(3):741-50.PMID: 12606516 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of glucagon-like peptide-1(7-36) and exendin-4 on the vascular reactivity in streptozotocin/nicotinamide-induced diabetic rats.

Ozyazgan S, Kutluata N, Afşar S, Ozdaş SB, Akkan AG.

Pharmacology. 2005 Jun;74(3):119-26. Epub 2005 Mar 3.PMID: 15746570 [PubMed - indexed for MEDLINE]Related articles

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

Xu G, Stoffers DA, Habener JF, Bonner-Weir S.

Diabetes. 1999 Dec;48(12):2270-6.PMID: 10580413 [PubMed - indexed for MEDLINE]Related articlesFree article

Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations.

Greig NH, Holloway HW, De Ore KA, Jani D, Wang Y, Zhou J, Garant MJ, Egan JM.

Diabetologia. 1999 Jan;42(1):45-50.PMID: 10027577 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats.

Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U, Perfetti R.

Endocrinology. 2002 Nov;143(11):4397-408.PMID: 12399437 [PubMed - indexed for MEDLINE]Related articlesFree article

Peptidergic regulation of maturation of the stimulus-secretion coupling in fetal islet beta cells.

Sjöholm A, Sandberg E, Ostenson CG, Efendić S.

Pancreas. 2000 Apr;20(3):282-9.PMID: 10766455 [PubMed - indexed for MEDLINE]Related articles

Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat.

Movassat J, Saulnier C, Serradas P, Portha B.

Diabetologia. 1997 Aug;40(8):916-25.PMID: 9267986 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1.

Doyle ME, Egan JM.

Recent Prog Horm Res. 2001;56:377-99. Review.PMID: 11237222 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin secretion and glucose tolerance after islet transplantation in rats with noninsulin-dependent diabetes induced by neonatal streptozotocin.

Tormo MA, Leon-Quinto T, Saulnier C, Bailbe D, Serradas P, Portha B.

Cell Transplant. 1997 Jan-Feb;6(1):23-32.PMID: 9040952 [PubMed - indexed for MEDLINE]Related articles

Exenatide (exendin-4) improves insulin sensitivity and {beta}-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight.

Gedulin BR, Nikoulina SE, Smith PA, Gedulin G, Nielsen LL, Baron AD, Parkes DG, Young AA.

Endocrinology. 2005 Apr;146(4):2069-76. Epub 2004 Dec 23.PMID: 15618356 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of endogenous glucagon-like peptide-1(7-36) amide on glycaemia-lowering effect of oligofructose in streptozotocin-treated rats.

Cani PD, Daubioul CA, Reusens B, Remacle C, Catillon G, Delzenne NM.

J Endocrinol. 2005 Jun;185(3):457-65.PMID: 15930172 [PubMed - indexed for MEDLINE]Related articlesFree article

Normalization of insulin responses to glucose by overnight infusion of glucagon-like peptide 1 (7-36) amide in patients with NIDDM.

Rachman J, Gribble FM, Barrow BA, Levy JC, Buchanan KD, Turner RC.

Diabetes. 1996 Nov;45(11):1524-30.PMID: 8866556 [PubMed - indexed for MEDLINE]Related articles

Ghrelin prevents development of diabetes at adult age in streptozotocin-treated newborn rats.

Irako T, Akamizu T, Hosoda H, Iwakura H, Ariyasu H, Tojo K, Tajima N, Kangawa K.

Diabetologia. 2006 Jun;49(6):1264-73. Epub 2006 Mar 29.PMID: 16570155 [PubMed - indexed for MEDLINE]Related articles