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Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells.
Nakagami H, Morishita R, Yamamoto K, Yoshimura SI, Taniyama Y, Aoki M, Matsubara H, Kim S, Kaneda Y, Ogihara T.
Diabetes. 2001 Jun;50(6):1472-81.PMID: 11375350 [PubMed - indexed for MEDLINE]Related articlesFree article
Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.
Park MT, Choi JA, Kim MJ, Um HD, Bae S, Kang CM, Cho CK, Kang S, Chung HY, Lee YS, Lee SJ.
J Biol Chem. 2003 Dec 12;278(50):50624-34. Epub 2003 Sep 30.PMID: 14522966 [PubMed - indexed for MEDLINE]Related articlesFree article
Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane.
Nakagami H, Morishita R, Yamamoto K, Taniyama Y, Aoki M, Yamasaki K, Matsumoto K, Nakamura T, Kaneda Y, Ogihara T.
Diabetes. 2002 Aug;51(8):2604-11.PMID: 12145177 [PubMed - indexed for MEDLINE]Related articlesFree article
Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogen-activated protein kinase pathway.
Yu C, Wang S, Dent P, Grant S.
Mol Pharmacol. 2001 Jul;60(1):143-54. Erratum in: Mol Pharmacol 2001 Aug;60(2):403. PMID: 11408609 [PubMed - indexed for MEDLINE]Related articlesFree article
p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L).
Grethe S, Ares MP, Andersson T, Pörn-Ares MI.
Exp Cell Res. 2004 Aug 15;298(2):632-42.PMID: 15265709 [PubMed - indexed for MEDLINE]Related articles
The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process.
Rahmani M, Dai Y, Grant S.
Exp Cell Res. 2002 Jul 1;277(1):31-47.PMID: 12061815 [PubMed - indexed for MEDLINE]Related articles
Chronic exposure of human mesangial cells to high glucose environments activates the p38 MAPK pathway.
Wilmer WA, Dixon CL, Hebert C.
Kidney Int. 2001 Sep;60(3):858-71.PMID: 11532081 [PubMed - indexed for MEDLINE]Related articlesFree article
Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
Choi JA, Park MT, Kang CM, Um HD, Bae S, Lee KH, Kim TH, Kim JH, Cho CK, Lee YS, Chung HY, Lee SJ.
Oncogene. 2004 Jan 8;23(1):9-20.PMID: 14712206 [PubMed - indexed for MEDLINE]Related articles
Role of p38 mitogen-activated protein kinase phosphorylation and Fas-Fas ligand interaction in morphine-induced macrophage apoptosis.
Singhal PC, Bhaskaran M, Patel J, Patel K, Kasinath BS, Duraisamy S, Franki N, Reddy K, Kapasi AA.
J Immunol. 2002 Apr 15;168(8):4025-33.PMID: 11937560 [PubMed - indexed for MEDLINE]Related articlesFree article
Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells.
Choi SY, Kim MJ, Kang CM, Bae S, Cho CK, Soh JW, Kim JH, Kang S, Chung HY, Lee YS, Lee SJ.
J Biol Chem. 2006 Mar 17;281(11):7049-59. Epub 2006 Jan 12.PMID: 16410245 [PubMed - indexed for MEDLINE]Related articlesFree article
Daxx deletion mutant (amino acids 501-625)-induced apoptosis occurs through the JNK/p38-Bax-dependent mitochondrial pathway.
Song JJ, Lee YJ.
J Cell Biochem. 2004 Aug 15;92(6):1257-70.PMID: 15258908 [PubMed - indexed for MEDLINE]Related articles
Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.
Gratton JP, Morales-Ruiz M, Kureishi Y, Fulton D, Walsh K, Sessa WC.
J Biol Chem. 2001 Aug 10;276(32):30359-65. Epub 2001 May 31.PMID: 11387313 [PubMed - indexed for MEDLINE]Related articlesFree article
p38 Mitogen-activated protein kinase regulates Bax translocation in cyanide-induced apoptosis.
Shou Y, Li L, Prabhakaran K, Borowitz JL, Isom GE.
Toxicol Sci. 2003 Sep;75(1):99-107. Epub 2003 Jun 12.PMID: 12805646 [PubMed - indexed for MEDLINE]Related articlesFree article
Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 Cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells.
Shiah SG, Chuang SE, Kuo ML.
Mol Pharmacol. 2001 Feb;59(2):254-62.PMID: 11160861 [PubMed - indexed for MEDLINE]Related articlesFree article
The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.
Kang YH, Lee SJ.
J Cell Physiol. 2008 Oct;217(1):23-33.PMID: 18412143 [PubMed - indexed for MEDLINE]Related articles
TL1, a novel tumor necrosis factor-like cytokine, induces apoptosis in endothelial cells. Involvement of activation of stress protein kinases (stress-activated protein kinase and p38 mitogen-activated protein kinase) and caspase-3-like protease.
Yue TL, Ni J, Romanic AM, Gu JL, Keller P, Wang C, Kumar S, Yu GL, Hart TK, Wang X, Xia Z, DeWolf WE Jr, Feuerstein GZ.
J Biol Chem. 1999 Jan 15;274(3):1479-86.PMID: 9880523 [PubMed - indexed for MEDLINE]Related articlesFree article
ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death.
Sarker KP, Biswas KK, Yamakuchi M, Lee KY, Hahiguchi T, Kracht M, Kitajima I, Maruyama I.
J Neurochem. 2003 Apr;85(1):50-61.PMID: 12641726 [PubMed - indexed for MEDLINE]Related articles
A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation.
Miyoshi N, Uchida K, Osawa T, Nakamura Y.
Cancer Res. 2004 Mar 15;64(6):2134-42.PMID: 15026354 [PubMed - indexed for MEDLINE]Related articlesFree article
Streptococcus pneumoniae R6x induced p38 MAPK and JNK-mediated caspase-dependent apoptosis in human endothelial cells.
N'Guessan PD, Schmeck B, Ayim A, Hocke AC, Brell B, Hammerschmidt S, Rosseau S, Suttorp N, Hippenstiel S.
Thromb Haemost. 2005 Aug;94(2):295-303.PMID: 16113818 [PubMed - indexed for MEDLINE]Related articles
Interactions between p38 mitogen-activated protein kinase and caspase-3 in cerebral endothelial cell death after hypoxia-reoxygenation.
Lee SR, Lo EH.
Stroke. 2003 Nov;34(11):2704-9. Epub 2003 Oct 9.PMID: 14551401 [PubMed - indexed for MEDLINE]Related articlesFree article
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