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    Results: 1 to 20 of 366

    1.

    Subcellular localization of insulin receptor substrate family proteins associated with phosphatidylinositol 3-kinase activity and alterations in lipolysis in primary mouse adipocytes from IRS-1 null mice.

    Tsuji Y, Kaburagi Y, Terauchi Y, Satoh S, Kubota N, Tamemoto H, Kraemer FB, Sekihara H, Aizawa S, Akanuma Y, Tobe K, Kimura S, Kadowaki T.

    Diabetes. 2001 Jun;50(6):1455-63.PMID: 11375348 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Different subcellular distribution and regulation of expression of insulin receptor substrate (IRS)-3 from those of IRS-1 and IRS-2.

    Anai M, Ono H, Funaki M, Fukushima Y, Inukai K, Ogihara T, Sakoda H, Onishi Y, Yazaki Y, Kikuchi M, Oka Y, Asano T.

    J Biol Chem. 1998 Nov 6;273(45):29686-92.PMID: 9792680 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes.

    Fasshauer M, Klein J, Ueki K, Kriauciunas KM, Benito M, White MF, Kahn CR.

    J Biol Chem. 2000 Aug 18;275(33):25494-501.PMID: 10829031 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes.

    Fasshauer M, Klein J, Kriauciunas KM, Ueki K, Benito M, Kahn CR.

    Mol Cell Biol. 2001 Jan;21(1):319-29.PMID: 11113206 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton.

    Clark SF, Martin S, Carozzi AJ, Hill MM, James DE.

    J Cell Biol. 1998 Mar 9;140(5):1211-25.PMID: 9490733 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle.

    Kelly KL, Ruderman NB.

    J Biol Chem. 1993 Feb 25;268(6):4391-8.PMID: 8382701 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Insulin signaling in insulin receptor substrate (IRS)-1-deficient brown adipocytes: requirement of IRS-1 for lipid synthesis.

    Valverde AM, Kahn CR, Benito M.

    Diabetes. 1999 Nov;48(11):2122-31.PMID: 10535444 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Regulation of insulin receptor, insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-F442A adipocytes. Effects of differentiation, insulin, and dexamethasone.

    Saad MJ, Folli F, Araki E, Hashimoto N, Csermely P, Kahn CR.

    Mol Endocrinol. 1994 May;8(5):545-57.PMID: 7520127 [PubMed - indexed for MEDLINE]Related articles

    9.

    Reciprocal feedback regulation of insulin receptor and insulin receptor substrate tyrosine phosphorylation by phosphoinositide 3-kinase in primary adipocytes.

    Hers I, Bell CJ, Poole AW, Jiang D, Denton RM, Schaefer E, Tavaré JM.

    Biochem J. 2002 Dec 15;368(Pt 3):875-84.PMID: 12220227 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Insulin signaling after exercise in insulin receptor substrate-2-deficient mice.

    Howlett KF, Sakamoto K, Hirshman MF, Aschenbach WG, Dow M, White MF, Goodyear LJ.

    Diabetes. 2002 Feb;51(2):479-83.PMID: 11812758 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Role of IRS-3 in the insulin signaling of IRS-1-deficient brown adipocytes.

    Arribas M, Valverde AM, Benito M.

    J Biol Chem. 2003 Nov 14;278(46):45189-99. Epub 2003 Aug 27.PMID: 12944402 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Role of insulin receptor substrate-1 and pp60 in the regulation of insulin-induced glucose transport and GLUT4 translocation in primary adipocytes.

    Kaburagi Y, Satoh S, Tamemoto H, Yamamoto-Honda R, Tobe K, Veki K, Yamauchi T, Kono-Sugita E, Sekihara H, Aizawa S, Cushman SW, Akanuma Y, Yazaki Y, Kadowaki T.

    J Biol Chem. 1997 Oct 10;272(41):25839-44.PMID: 9325314 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes.

    Valverde AM, Arribas M, Mur C, Navarro P, Pons S, Cassard-Doulcier AM, Kahn CR, Benito M.

    J Biol Chem. 2003 Mar 21;278(12):10221-31. Epub 2003 Jan 13.PMID: 12525499 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Insulin receptor substrate 3 is not essential for growth or glucose homeostasis.

    Liu SC, Wang Q, Lienhard GE, Keller SR.

    J Biol Chem. 1999 Jun 18;274(25):18093-9.PMID: 10364263 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway.

    Zierath JR, Livingston JN, Thörne A, Bolinder J, Reynisdottir S, Lönnqvist F, Arner P.

    Diabetologia. 1998 Nov;41(11):1343-54.PMID: 9833943 [PubMed - indexed for MEDLINE]Related articles

    16.

    Insulin-like growth factor-1 (IGF-1) receptor-insulin receptor substrate complexes in the uterus. Altered signaling response to estradiol in the IGF-1(m/m) mouse.

    Richards RG, Walker MP, Sebastian J, DiAugustine RP.

    J Biol Chem. 1998 May 8;273(19):11962-9.PMID: 9565625 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes.

    Takano A, Haruta T, Iwata M, Usui I, Uno T, Kawahara J, Ueno E, Sasaoka T, Kobayashi M.

    Diabetes. 2001 Aug;50(8):1891-900.PMID: 11473053 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.

    Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M.

    Mol Cell Biol. 2001 Mar;21(5):1633-46.PMID: 11238900 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.

    Valverde AM, Lorenzo M, Pons S, White MF, Benito M.

    Mol Endocrinol. 1998 May;12(5):688-97.PMID: 9605931 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    beta(3)-adrenergic stimulation differentially inhibits insulin signaling and decreases insulin-induced glucose uptake in brown adipocytes.

    Klein J, Fasshauer M, Ito M, Lowell BB, Benito M, Kahn CR.

    J Biol Chem. 1999 Dec 3;274(49):34795-802.PMID: 10574950 [PubMed - indexed for MEDLINE]Related articlesFree article

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