PubMed

IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress.

Kajstura J, Fiordaliso F, Andreoli AM, Li B, Chimenti S, Medow MS, Limana F, Nadal-Ginard B, Leri A, Anversa P.

Diabetes. 2001 Jun;50(6):1414-24.PMID: 11375343 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice.

Leri A, Liu Y, Wang X, Kajstura J, Malhotra A, Meggs LG, Anversa P.

Circ Res. 1999 Apr 16;84(7):752-62.PMID: 10205143 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis.

Leri A, Liu Y, Claudio PP, Kajstura J, Wang X, Wang S, Kang P, Malhotra A, Anversa P.

Am J Pathol. 1999 Feb;154(2):567-80.PMID: 10027414 [PubMed - indexed for MEDLINE]Related articlesFree article

Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.

Zhou G, Li X, Hein DW, Xiang X, Marshall JP, Prabhu SD, Cai L.

J Am Coll Cardiol. 2008 Aug 19;52(8):655-66.PMID: 18702970 [PubMed - indexed for MEDLINE]Related articles

Inhibition of p53 function prevents renin-angiotensin system activation and stretch-mediated myocyte apoptosis.

Leri A, Fiordaliso F, Setoguchi M, Limana F, Bishopric NH, Kajstura J, Webster K, Anversa P.

Am J Pathol. 2000 Sep;157(3):843-57.PMID: 10980124 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death.

Fiordaliso F, Leri A, Cesselli D, Limana F, Safai B, Nadal-Ginard B, Anversa P, Kajstura J.

Diabetes. 2001 Oct;50(10):2363-75.PMID: 11574421 [PubMed - indexed for MEDLINE]Related articlesFree article

Canine ventricular myocytes possess a renin-angiotensin system that is upregulated with heart failure.

Barlucchi L, Leri A, Dostal DE, Fiordaliso F, Tada H, Hintze TH, Kajstura J, Nadal-Ginard B, Anversa P.

Circ Res. 2001 Feb 16;88(3):298-304.PMID: 11179197 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial cell death in human diabetes.

Frustaci A, Kajstura J, Chimenti C, Jakoniuk I, Leri A, Maseri A, Nadal-Ginard B, Anversa P.

Circ Res. 2000 Dec 8;87(12):1123-32.PMID: 11110769 [PubMed - indexed for MEDLINE]Related articlesFree article

Ischemic cardiomyopathy and the cellular renin-angiotensin system.

Anversa P, Leri A, Li B, Liu Y, Di Somma S, Kajstura J.

J Heart Lung Transplant. 2000 Aug;19(8 Suppl):S1-11. Review.PMID: 11016481 [PubMed - indexed for MEDLINE]Related articles

Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell.

Leri A, Claudio PP, Li Q, Wang X, Reiss K, Wang S, Malhotra A, Kajstura J, Anversa P.

J Clin Invest. 1998 Apr 1;101(7):1326-42.PMID: 9525975 [PubMed - indexed for MEDLINE]Related articlesFree article

Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy.

Cai L, Wang Y, Zhou G, Chen T, Song Y, Li X, Kang YJ.

J Am Coll Cardiol. 2006 Oct 17;48(8):1688-97. Epub 2006 Sep 27.PMID: 17045908 [PubMed - indexed for MEDLINE]Related articles

Myocyte death in streptozotocin-induced diabetes in rats in angiotensin II- dependent.

Fiordaliso F, Li B, Latini R, Sonnenblick EH, Anversa P, Leri A, Kajstura J.

Lab Invest. 2000 Apr;80(4):513-27.PMID: 10780668 [PubMed - indexed for MEDLINE]Related articles

Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression.

Torella D, Rota M, Nurzynska D, Musso E, Monsen A, Shiraishi I, Zias E, Walsh K, Rosenzweig A, Sussman MA, Urbanek K, Nadal-Ginard B, Kajstura J, Anversa P, Leri A.

Circ Res. 2004 Mar 5;94(4):514-24. Epub 2004 Jan 15.PMID: 14726476 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperglycemia activates JAK2 signaling pathway in human failing myocytes via angiotensin II-mediated oxidative stress.

Modesti A, Bertolozzi I, Gamberi T, Marchetta M, Lumachi C, Coppo M, Moroni F, Toscano T, Lucchese G, Gensini GF, Modesti PA.

Diabetes. 2005 Feb;54(2):394-401.PMID: 15677497 [PubMed - indexed for MEDLINE]Related articlesFree article

p53 Induces myocyte apoptosis via the activation of the renin-angiotensin system.

Pierzchalski P, Reiss K, Cheng W, Cirielli C, Kajstura J, Nitahara JA, Rizk M, Capogrossi MC, Anversa P.

Exp Cell Res. 1997 Jul 10;234(1):57-65.PMID: 9223370 [PubMed - indexed for MEDLINE]Related articles

Inhibition of p66ShcA redox activity in cardiac muscle cells attenuates hyperglycemia-induced oxidative stress and apoptosis.

Malhotra A, Vashistha H, Yadav VS, Dube MG, Kalra SP, Abdellatif M, Meggs LG.

Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H380-8. Epub 2008 Dec 5.PMID: 19060130 [PubMed - indexed for MEDLINE]Related articles

Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and beta-adrenergic response in ventricular myocytes.

Norby FL, Aberle NS 2nd, Kajstura J, Anversa P, Ren J.

J Endocrinol. 2004 Jan;180(1):175-82.PMID: 14709156 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy.

Cesselli D, Jakoniuk I, Barlucchi L, Beltrami AP, Hintze TH, Nadal-Ginard B, Kajstura J, Leri A, Anversa P.

Circ Res. 2001 Aug 3;89(3):279-86.PMID: 11485979 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis.

Singh VP, Le B, Khode R, Baker KM, Kumar R.

Diabetes. 2008 Dec;57(12):3297-306. Epub 2008 Oct 1. Erratum in: Diabetes. 2009 Mar;58(3):770. PMID: 18829990 [PubMed - indexed for MEDLINE]Related articlesFree article

Release of preformed Ang II from myocytes mediates angiotensinogen and ET-1 gene overexpression in vivo via AT1 receptor.

Amedeo Modesti P, Zecchi-Orlandini S, Vanni S, Polidori G, Bertolozzi I, Perna AM, Formigli L, Cecioni I, Coppo M, Boddi M, Serneri GG.

J Mol Cell Cardiol. 2002 Nov;34(11):1491-500.PMID: 12431448 [PubMed - indexed for MEDLINE]Related articles