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    Results: 1 to 20 of 256

    1.

    Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays.

    Cardozo AK, Kruhøffer M, Leeman R, Orntoft T, Eizirik DL.

    Diabetes. 2001 May;50(5):909-20.PMID: 11334433 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Double-stranded ribonucleic acid (RNA) induces beta-cell Fas messenger RNA expression and increases cytokine-induced beta-cell apoptosis.

    Liu D, Darville M, Eizirik DL.

    Endocrinology. 2001 Jun;142(6):2593-9.PMID: 11356709 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    IL-1beta induces serine protease inhibitor 3 (SPI-3) gene expression in rat pancreatic beta-cells. Detection by differential display of messenger RNA.

    Chen MC, Schuit F, Pipeleers DG, Eizirik DL.

    Cytokine. 1999 Nov;11(11):856-62.PMID: 10547273 [PubMed - indexed for MEDLINE]Related articles

    4.

    Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus.

    Liu D, Cardozo AK, Darville MI, Eizirik DL.

    Endocrinology. 2002 Apr;143(4):1225-34.PMID: 11897677 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.

    Kutlu B, Cardozo AK, Darville MI, Kruhøffer M, Magnusson N, Ørntoft T, Eizirik DL.

    Diabetes. 2003 Nov;52(11):2701-19.PMID: 14578289 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cells.

    Pavlovic D, Chen MC, Gysemans CA, Mathieu C, Eizirik DL.

    Eur Cytokine Netw. 1999 Sep;10(3):403-12.PMID: 10477397 [PubMed - indexed for MEDLINE]Related articles

    7.

    Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets.

    Ylipaasto P, Kutlu B, Rasilainen S, Rasschaert J, Salmela K, Teerijoki H, Korsgren O, Lahesmaa R, Hovi T, Eizirik DL, Otonkoski T, Roivainen M.

    Diabetologia. 2005 Aug;48(8):1510-22. Epub 2005 Jul 1.PMID: 15991020 [PubMed - indexed for MEDLINE]Related articles

    8.

    Cytokine induction of Fas gene expression in insulin-producing cells requires the transcription factors NF-kappaB and C/EBP.

    Darville MI, Eizirik DL.

    Diabetes. 2001 Aug;50(8):1741-8.PMID: 11473033 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity.

    Karlsen AE, Rønn SG, Lindberg K, Johannesen J, Galsgaard ED, Pociot F, Nielsen JH, Mandrup-Poulsen T, Nerup J, Billestrup N.

    Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12191-6. Epub 2001 Oct 2.PMID: 11593036 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells.

    Chen MC, Proost P, Gysemans C, Mathieu C, Eizirik DL.

    Diabetologia. 2001 Mar;44(3):325-32.PMID: 11317664 [PubMed - indexed for MEDLINE]Related articles

    11.

    Global profiling of double stranded RNA- and IFN-gamma-induced genes in rat pancreatic beta cells.

    Rasschaert J, Liu D, Kutlu B, Cardozo AK, Kruhøffer M, ØRntoft TF, Eizirik DL.

    Diabetologia. 2003 Dec;46(12):1641-57. Epub 2003 Nov 5.PMID: 14600816 [PubMed - indexed for MEDLINE]Related articles

    12.

    Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.

    Kharroubi I, Ladrière L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL.

    Endocrinology. 2004 Nov;145(11):5087-96. Epub 2004 Aug 5.PMID: 15297438 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells.

    Ortis F, Pirot P, Naamane N, Kreins AY, Rasschaert J, Moore F, Théâtre E, Verhaeghe C, Magnusson NE, Chariot A, Orntoft TF, Eizirik DL.

    Diabetologia. 2008 Jul;51(7):1213-25. Epub 2008 May 8.PMID: 18463842 [PubMed - indexed for MEDLINE]Related articles

    14.

    Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma -mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells.

    Dupraz P, Cottet S, Hamburger F, Dolci W, Felley-Bosco E, Thorens B.

    J Biol Chem. 2000 Dec 1;275(48):37672-8.PMID: 10967106 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Identification of IL-1beta-induced messenger RNAs in rat pancreatic beta cells by differential display of messenger RNA.

    Chen MC, Schuit F, Eizirik DL.

    Diabetologia. 1999 Oct;42(10):1199-203.PMID: 10525660 [PubMed - indexed for MEDLINE]Related articles

    16.

    A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells.

    Cardozo AK, Heimberg H, Heremans Y, Leeman R, Kutlu B, Kruhøffer M, Ørntoft T, Eizirik DL.

    J Biol Chem. 2001 Dec 28;276(52):48879-86. Epub 2001 Oct 30.PMID: 11687580 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation.

    Ortis F, Cardozo AK, Crispim D, Störling J, Mandrup-Poulsen T, Eizirik DL.

    Mol Endocrinol. 2006 Aug;20(8):1867-79. Epub 2006 Mar 23.PMID: 16556731 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

    Liu D, Pavlovic D, Chen MC, Flodström M, Sandler S, Eizirik DL.

    Diabetes. 2000 Jul;49(7):1116-22.PMID: 10909967 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

    Cardozo AK, Proost P, Gysemans C, Chen MC, Mathieu C, Eizirik DL.

    Diabetologia. 2003 Feb;46(2):255-66. Epub 2003 Feb 12.PMID: 12627325 [PubMed - indexed for MEDLINE]Related articles

    20.

    New approaches for in silico identification of cytokine-modified beta cell gene networks.

    Kutlu B, Naamane N, Berthou L, Eizirik DL.

    Ann N Y Acad Sci. 2004 Dec;1037:41-58. Review.PMID: 15699492 [PubMed - indexed for MEDLINE]Related articles

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