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The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia.
Ahrén B, Holst JJ.
Diabetes. 2001 May;50(5):1030-8.PMID: 11334405 [PubMed - indexed for MEDLINE]Related articlesFree article
Activation of the parasympathetic nervous system is necessary for normal meal-induced insulin secretion in rhesus macaques.
D'Alessio DA, Kieffer TJ, Taborsky GJ Jr, Havel PJ.
J Clin Endocrinol Metab. 2001 Mar;86(3):1253-9.PMID: 11238517 [PubMed - indexed for MEDLINE]Related articlesFree article
Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects.
Vilsbøll T, Krarup T, Madsbad S, Holst JJ.
Regul Pept. 2003 Jul 15;114(2-3):115-21.PMID: 12832099 [PubMed - indexed for MEDLINE]Related articles
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.
Vilsbøll T, Krarup T, Deacon CF, Madsbad S, Holst JJ.
Diabetes. 2001 Mar;50(3):609-13.PMID: 11246881 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans.
Nauck MA, Niedereichholz U, Ettler R, Holst JJ, Orskov C, Ritzel R, Schmiegel WH.
Am J Physiol. 1997 Nov;273(5 Pt 1):E981-8.PMID: 9374685 [PubMed - indexed for MEDLINE]Related articlesFree article
Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men.
Rask E, Olsson T, Söderberg S, Johnson O, Seckl J, Holst JJ, Ahrén B; Northern Sweden Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA).
Diabetes Care. 2001 Sep;24(9):1640-5.PMID: 11522713 [PubMed - indexed for MEDLINE]Related articlesFree article
Erythromycin antagonizes the deceleration of gastric emptying by glucagon-like peptide 1 and unmasks its insulinotropic effect in healthy subjects.
Meier JJ, Kemmeries G, Holst JJ, Nauck MA.
Diabetes. 2005 Jul;54(7):2212-8.PMID: 15983224 [PubMed - indexed for MEDLINE]Related articlesFree article
Activation of autonomic nerves and the adrenal medulla contributes to increased glucagon secretion during moderate insulin-induced hypoglycemia in women.
Havel PJ, Ahren B.
Diabetes. 1997 May;46(5):801-7.PMID: 9133547 [PubMed - indexed for MEDLINE]Related articles
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus.
Vilsbøll T, Krarup T, Sonne J, Madsbad S, Vølund A, Juul AG, Holst JJ.
J Clin Endocrinol Metab. 2003 Jun;88(6):2706-13.PMID: 12788877 [PubMed - indexed for MEDLINE]Related articlesFree article
Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)--evidence for decreased glucagon-like peptide 1 secretion during oral glucose ingestion in NIDDM twins.
Vaag AA, Holst JJ, Vølund A, Beck-Nielsen HB.
Eur J Endocrinol. 1996 Oct;135(4):425-32.PMID: 8921824 [PubMed - indexed for MEDLINE]Related articles
Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans.
Ahrén B, Holst JJ, Mari A.
Diabetes Care. 2003 Oct;26(10):2860-4.PMID: 14514592 [PubMed - indexed for MEDLINE]Related articlesFree article
The effects of miglitol on glucagon-like peptide-1 secretion and appetite sensations in obese type 2 diabetics.
Lee A, Patrick P, Wishart J, Horowitz M, Morley JE.
Diabetes Obes Metab. 2002 Sep;4(5):329-35.PMID: 12190996 [PubMed - indexed for MEDLINE]Related articles
Initially more rapid small intestinal glucose delivery increases plasma insulin, GIP, and GLP-1 but does not improve overall glycemia in healthy subjects.
Chaikomin R, Doran S, Jones KL, Feinle-Bisset C, O'Donovan D, Rayner CK, Horowitz M.
Am J Physiol Endocrinol Metab. 2005 Sep;289(3):E504-7. Epub 2005 May 10.PMID: 15886226 [PubMed - indexed for MEDLINE]Related articlesFree article
Postprandial hormone and metabolic responses in simulated shift work.
Hampton SM, Morgan LM, Lawrence N, Anastasiadou T, Norris F, Deacon S, Ribeiro D, Arendt J.
J Endocrinol. 1996 Nov;151(2):259-67.PMID: 8958786 [PubMed - indexed for MEDLINE]Related articles
Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance.
Rask E, Olsson T, Söderberg S, Holst Jj J, Tura A, Pacini G, Ahrén B.
Metabolism. 2004 May;53(5):624-31.PMID: 15131768 [PubMed - indexed for MEDLINE]Related articles
alpha-Glucosidase inhibition (acarbose) fails to enhance secretion of glucagon-like peptide 1 (7-36 amide) and to delay gastric emptying in Type 2 diabetic patients.
Hücking K, Kostic Z, Pox C, Ritzel R, Holst JJ, Schmiegel W, Nauck MA.
Diabet Med. 2005 Apr;22(4):470-6.PMID: 15787675 [PubMed - indexed for MEDLINE]Related articles
Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects.
Frid AH, Nilsson M, Holst JJ, Björck IM.
Am J Clin Nutr. 2005 Jul;82(1):69-75.PMID: 16002802 [PubMed - indexed for MEDLINE]Related articlesFree article
Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects.
Meier JJ, Nauck MA, Kranz D, Holst JJ, Deacon CF, Gaeckler D, Schmidt WE, Gallwitz B.
Diabetes. 2004 Mar;53(3):654-62.PMID: 14988249 [PubMed - indexed for MEDLINE]Related articlesFree article
The role of postprandial releases of insulin and incretin hormones in meal-induced satiety--effect of obesity and weight reduction.
Verdich C, Toubro S, Buemann B, Lysgård Madsen J, Juul Holst J, Astrup A.
Int J Obes Relat Metab Disord. 2001 Aug;25(8):1206-14.PMID: 11477506 [PubMed - indexed for MEDLINE]Related articlesFree article
Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes.
Højberg PV, Vilsbøll T, Zander M, Knop FK, Krarup T, Vølund A, Holst JJ, Madsbad S.
Diabet Med. 2008 Nov;25(11):1268-75.PMID: 19046215 [PubMed - indexed for MEDLINE]Related articles
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