PubMed

Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells.

Hui H, Wright C, Perfetti R.

Diabetes. 2001 Apr;50(4):785-96.PMID: 11289043 [PubMed - indexed for MEDLINE]Related articlesFree article

Cultured pancreatic ductal cells undergo cell cycle re-distribution and beta-cell-like differentiation in response to glucagon-like peptide-1.

Bulotta A, Hui H, Anastasi E, Bertolotto C, Boros LG, Di Mario U, Perfetti R.

J Mol Endocrinol. 2002 Dec;29(3):347-60.PMID: 12459036 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells.

Abraham EJ, Leech CA, Lin JC, Zulewski H, Habener JF.

Endocrinology. 2002 Aug;143(8):3152-61.PMID: 12130581 [PubMed - indexed for MEDLINE]Related articlesFree article

Transfection of pancreatic-derived beta-cells with a minigene encoding for human glucagon-like peptide-1 regulates glucose-dependent insulin synthesis and secretion.

Hui H, Yu R, Bousquet C, Perfetti R.

Endocrinology. 2002 Sep;143(9):3529-39. Erratum in: Endocrinology 2002 Nov;143(11):4349. PMID: 12193567 [PubMed - indexed for MEDLINE]Related articlesFree article

GLP-1 stimulates glucose-derived de novo fatty acid synthesis and chain elongation during cell differentiation and insulin release.

Bulotta A, Perfetti R, Hui H, Boros LG.

J Lipid Res. 2003 Aug;44(8):1559-65. Epub 2003 Jun 1.PMID: 12777469 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1.

Doyle ME, Egan JM.

Recent Prog Horm Res. 2001;56:377-99. Review.PMID: 11237222 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic epithelial cells can be converted into insulin-producing cells by GLP-1 in conjunction with virus-mediated gene transfer of pdx-1.

Koizumi M, Doi R, Fujimoto K, Ito D, Toyoda E, Mori T, Kami K, Kawaguchi Y, Gittes GK, Imamura M.

Surgery. 2005 Aug;138(2):125-33.PMID: 16153418 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats.

Perfetti R, Zhou J, Doyle ME, Egan JM.

Endocrinology. 2000 Dec;141(12):4600-5.PMID: 11108273 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 increases glucose-dependent activity of the homeoprotein IDX-1 transactivating domain in pancreatic beta-cells.

Hussain MA, Habener JF.

Biochem Biophys Res Commun. 2000 Aug 11;274(3):616-9.PMID: 10924326 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism.

Wang X, Zhou J, Doyle ME, Egan JM.

Endocrinology. 2001 May;142(5):1820-7.PMID: 11316746 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 enhances production of insulin in insulin-producing cells derived from mouse embryonic stem cells.

Bai L, Meredith G, Tuch BE.

J Endocrinol. 2005 Aug;186(2):343-52.PMID: 16079260 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of a novel zinc-finger cDNA, IA-1, is associated with rat AR42J cells differentiation into insulin-positive cells.

Zhu M, Breslin MB, Lan MS.

Pancreas. 2002 Mar;24(2):139-45.PMID: 11854618 [PubMed - indexed for MEDLINE]Related articles

Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factors.

Zhou J, Pineyro MA, Wang X, Doyle ME, Egan JM.

J Cell Physiol. 2002 Sep;192(3):304-14.PMID: 12124776 [PubMed - indexed for MEDLINE]Related articles

The acquisition of an insulin-secreting phenotype by HGF-treated rat pancreatic ductal cells (ARIP) is associated with the development of susceptibility to cytokine-induced apoptosis.

Anastasi E, Santangelo C, Bulotta A, Dotta F, Argenti B, Mincione C, Gulino A, Maroder M, Perfetti R, Di Mario U.

J Mol Endocrinol. 2005 Apr;34(2):367-76.PMID: 15821103 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional maturation of fetal porcine beta-cells by glucagon-like peptide 1 and cholecystokinin.

Hardikar AA, Wang XY, Williams LJ, Kwok J, Wong R, Yao M, Tuch BE.

Endocrinology. 2002 Sep;143(9):3505-14.PMID: 12193564 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells.

Zhou J, Wang X, Pineyro MA, Egan JM.

Diabetes. 1999 Dec;48(12):2358-66.PMID: 10580424 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 affects gene transcription and messenger ribonucleic acid stability of components of the insulin secretory system in RIN 1046-38 cells.

Wang Y, Egan JM, Raygada M, Nadiv O, Roth J, Montrose-Rafizadeh C.

Endocrinology. 1995 Nov;136(11):4910-7.PMID: 7588224 [PubMed - indexed for MEDLINE]Related articles

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.

Stoffers DA, Kieffer TJ, Hussain MA, Drucker DJ, Bonner-Weir S, Habener JF, Egan JM.

Diabetes. 2000 May;49(5):741-8.PMID: 10905482 [PubMed - indexed for MEDLINE]Related articlesFree article

N-acetyl-GLP-1: a DPP IV-resistant analogue of glucagon-like peptide-1 (GLP-1) with improved effects on pancreatic beta-cell-associated gene expression.

Liu HK, Green BD, Gault VA, McCluskey JT, McClenaghan NH, O'Harte FP, Flatt PR.

Cell Biol Int. 2004;28(1):69-73.PMID: 14759771 [PubMed - indexed for MEDLINE]Related articles

Synergistic effect of dimethyl sulfoxide on glucagon-like peptide 1 (GLP-1)-stimulated insulin secretion and gene transcription in INS-1 cells: characterization and implications.

Kemp DM, Habener JF.

Biochem Pharmacol. 2002 Aug 15;64(4):689-97.PMID: 12167488 [PubMed - indexed for MEDLINE]Related articles