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Free fatty acids induce peripheral insulin resistance without increasing muscle hexosamine pathway product levels in rats.
Choi CS, Lee FN, Youn JH.
Diabetes. 2001 Feb;50(2):418-24.PMID: 11272156 [PubMed - indexed for MEDLINE]Related articlesFree article
Role of the glucosamine pathway in fat-induced insulin resistance.
Hawkins M, Barzilai N, Liu R, Hu M, Chen W, Rossetti L.
J Clin Invest. 1997 May 1;99(9):2173-82.PMID: 9151789 [PubMed - indexed for MEDLINE]Related articlesFree article
Plasma free fatty acids decrease insulin-stimulated skeletal muscle glucose uptake by suppressing glycolysis in conscious rats.
Kim JK, Wi JK, Youn JH.
Diabetes. 1996 Apr;45(4):446-53.PMID: 8603766 [PubMed - indexed for MEDLINE]Related articles
Increased hexosamine availability similarly impairs the action of insulin and IGF-1 on glucose disposal.
Hawkins M, Barzilai N, Chen W, Angelov I, Hu M, Cohen P, Rossetti L.
Diabetes. 1996 Dec;45(12):1734-43.PMID: 8922359 [PubMed - indexed for MEDLINE]Related articles
Prolonged suppression of glucose metabolism causes insulin resistance in rat skeletal muscle.
Kim JK, Youn JH.
Am J Physiol. 1997 Feb;272(2 Pt 1):E288-96.PMID: 9124337 [PubMed - indexed for MEDLINE]Related articles
Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance in multiple insulin sensitive tissues.
Virkamäki A, Daniels MC, Hämäläinen S, Utriainen T, McClain D, Yki-Järvinen H.
Endocrinology. 1997 Jun;138(6):2501-7.PMID: 9165041 [PubMed - indexed for MEDLINE]Related articlesFree article
Thiazolidinedione treatment prevents free fatty acid-induced insulin resistance in male wistar rats.
Hevener AL, Reichart D, Janez A, Olefsky J.
Diabetes. 2001 Oct;50(10):2316-22.PMID: 11574414 [PubMed - indexed for MEDLINE]Related articlesFree article
In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats.
Rossetti L, Hawkins M, Chen W, Gindi J, Barzilai N.
J Clin Invest. 1995 Jul;96(1):132-40.PMID: 7615783 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of different free fatty acids on insulin resistance in rats.
Han P, Zhang YY, Lu Y, He B, Zhang W, Xia F.
Hepatobiliary Pancreat Dis Int. 2008 Feb;7(1):91-6.PMID: 18234646 [PubMed - indexed for MEDLINE]Related articlesFree article
Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo.
Clerk LH, Rattigan S, Clark MG.
Diabetes. 2002 Apr;51(4):1138-45.PMID: 11916937 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucose-fatty acid cycle operates in humans at the levels of both whole body and skeletal muscle during low and high physiological plasma insulin concentrations.
Vaag AA, Handberg A, Skøtt P, Richter EA, Beck-Nielsen H.
Eur J Endocrinol. 1994 Jan;130(1):70-9.PMID: 8124481 [PubMed - indexed for MEDLINE]Related articles
Insulin regulation of skeletal muscle PDK4 mRNA expression is impaired in acute insulin-resistant states.
Kim YI, Lee FN, Choi WS, Lee S, Youn JH.
Diabetes. 2006 Aug;55(8):2311-7.PMID: 16873695 [PubMed - indexed for MEDLINE]Related articlesFree article
Insulin suppresses PDK-4 expression in skeletal muscle independently of plasma FFA.
Lee FN, Zhang L, Zheng D, Choi WS, Youn JH.
Am J Physiol Endocrinol Metab. 2004 Jul;287(1):E69-74. Epub 2004 Mar 16.PMID: 15026305 [PubMed - indexed for MEDLINE]Related articlesFree article
Chronic free fatty acid infusion in rats results in insulin resistance but no alteration in insulin-responsive glucose transporter levels in skeletal muscle.
Magnan C, Gilbert M, Kahn BB.
Lipids. 1996 Nov;31(11):1141-9.PMID: 8934446 [PubMed - indexed for MEDLINE]Related articles
Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle.
Patti ME, Virkamäki A, Landaker EJ, Kahn CR, Yki-Järvinen H.
Diabetes. 1999 Aug;48(8):1562-71.PMID: 10426374 [PubMed - indexed for MEDLINE]Related articlesFree article
Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation.
Kruszynska YT, Worrall DS, Ofrecio J, Frias JP, Macaraeg G, Olefsky JM.
J Clin Endocrinol Metab. 2002 Jan;87(1):226-34.PMID: 11788651 [PubMed - indexed for MEDLINE]Related articlesFree article
Acute effect of growth hormone to induce peripheral insulin resistance is independent of FFA and insulin levels in rats.
Kim JK, Choi CS, Youn JH.
Am J Physiol. 1999 Oct;277(4 Pt 1):E742-9.PMID: 10516135 [PubMed - indexed for MEDLINE]Related articlesFree article
Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.
Storgaard H, Jensen CB, Björnholm M, Song XM, Madsbad S, Zierath JR, Vaag AA.
J Clin Endocrinol Metab. 2004 Mar;89(3):1301-11.PMID: 15001626 [PubMed - indexed for MEDLINE]Related articlesFree article
Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo.
Park E, Wong V, Guan X, Oprescu AI, Giacca A.
J Endocrinol. 2007 Nov;195(2):323-31.PMID: 17951543 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicity.
Baron AD, Zhu JS, Zhu JH, Weldon H, Maianu L, Garvey WT.
J Clin Invest. 1995 Dec;96(6):2792-801.PMID: 8675649 [PubMed - indexed for MEDLINE]Related articlesFree article
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